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Seizure
Andrew T. Trout, MD
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KEY FACTS

  • Imaging

    • Clinical Issues

      TERMINOLOGY

      • Definitions

        • Seizure: Clinical manifestation of aberrant neuronal electrical discharge(s) in brain
        • Epilepsy: ≥ 2 unprovoked, afebrile seizures

      IMAGING

      • General Features

        • Nuclear Medicine Findings

          • MR Findings

            DIFFERENTIAL DIAGNOSIS

              PATHOLOGY

              • Gross Pathologic & Surgical Features

                • Microscopic Features

                  CLINICAL ISSUES

                  • Demographics

                    • Natural History & Prognosis

                      • Treatment

                        Selected References

                        1. Wong-Kisiel LC et al: Challenges in managing epilepsy associated with focal cortical dysplasia in children. Epilepsy Res. 145:1-17, 2018
                        2. Manford M: Recent advances in epilepsy. J Neurol. 264(8):1811-24, 2017
                        3. Mountz JM et al: Pediatric epilepsy: Neurology, functional imaging, and neurosurgery. Semin Nucl Med. 47(2):170-87, 2017
                        4. Duncan JS et al: Brain imaging in the assessment for epilepsy surgery. Lancet Neurol. 15(4):420-33, 2016
                        5. Miyata H et al: Surgical pathology of epilepsy-associated non-neoplastic cerebral lesions: a brief introduction with special reference to hippocampal sclerosis and focal cortical dysplasia. Neuropathology. 33(4):442-58, 2013
                        6. Sidhu R et al: Pediatric seizures. Pediatr Rev. 34(8):333-41; 342, 2013
                        7. Kim S et al: SPECT Imaging of epilepsy: An overview and comparison with F-18 FDG PET. Int J Mol Imaging. 2011:813028, 2011
                        8. O'Brien TJ et al: Subtraction peri-ictal SPECT is predictive of extratemporal epilepsy surgery outcome. Neurology. 55(11):1668-77, 2000
                        9. Won HJ et al: Comparison of MR imaging with PET and ictal SPECT in 118 patients with intractable epilepsy. AJNR Am J Neuroradiol. 20(4):593-9, 1999
                        10. Devous MD Sr et al: SPECT brain imaging in epilepsy: a meta-analysis. J Nucl Med. 39(2):285-93, 1998
                        Related Anatomy
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                        Related Differential Diagnoses
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                        References
                        Tables

                        Tables

                        KEY FACTS

                        • Imaging

                          • Clinical Issues

                            TERMINOLOGY

                            • Definitions

                              • Seizure: Clinical manifestation of aberrant neuronal electrical discharge(s) in brain
                              • Epilepsy: ≥ 2 unprovoked, afebrile seizures

                            IMAGING

                            • General Features

                              • Nuclear Medicine Findings

                                • MR Findings

                                  DIFFERENTIAL DIAGNOSIS

                                    PATHOLOGY

                                    • Gross Pathologic & Surgical Features

                                      • Microscopic Features

                                        CLINICAL ISSUES

                                        • Demographics

                                          • Natural History & Prognosis

                                            • Treatment

                                              Selected References

                                              1. Wong-Kisiel LC et al: Challenges in managing epilepsy associated with focal cortical dysplasia in children. Epilepsy Res. 145:1-17, 2018
                                              2. Manford M: Recent advances in epilepsy. J Neurol. 264(8):1811-24, 2017
                                              3. Mountz JM et al: Pediatric epilepsy: Neurology, functional imaging, and neurosurgery. Semin Nucl Med. 47(2):170-87, 2017
                                              4. Duncan JS et al: Brain imaging in the assessment for epilepsy surgery. Lancet Neurol. 15(4):420-33, 2016
                                              5. Miyata H et al: Surgical pathology of epilepsy-associated non-neoplastic cerebral lesions: a brief introduction with special reference to hippocampal sclerosis and focal cortical dysplasia. Neuropathology. 33(4):442-58, 2013
                                              6. Sidhu R et al: Pediatric seizures. Pediatr Rev. 34(8):333-41; 342, 2013
                                              7. Kim S et al: SPECT Imaging of epilepsy: An overview and comparison with F-18 FDG PET. Int J Mol Imaging. 2011:813028, 2011
                                              8. O'Brien TJ et al: Subtraction peri-ictal SPECT is predictive of extratemporal epilepsy surgery outcome. Neurology. 55(11):1668-77, 2000
                                              9. Won HJ et al: Comparison of MR imaging with PET and ictal SPECT in 118 patients with intractable epilepsy. AJNR Am J Neuroradiol. 20(4):593-9, 1999
                                              10. Devous MD Sr et al: SPECT brain imaging in epilepsy: a meta-analysis. J Nucl Med. 39(2):285-93, 1998