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Serous Cystadenoma
Akram M. Shaaban, MBBCh; Marcia C. Javitt, MD, FACR; Shephard S. Kosut, MD
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KEY FACTS

  • Terminology

    • Imaging

      • Top Differential Diagnoses

        • Clinical Issues

          • Diagnostic Checklist

            TERMINOLOGY

            • Definitions

              • Benign ovarian tumor classified as epithelial ovarian neoplasm
              • Thin-walled, serous fluid-containing cyst(s) lined by single layer of epithelium

            IMAGING

            • General Features

              • CT Findings

                • MR Findings

                  • Ultrasonographic Findings

                    • Nuclear Medicine Findings

                      • Imaging Recommendations

                        DIFFERENTIAL DIAGNOSIS

                          PATHOLOGY

                          • General Features

                            • Gross Pathologic & Surgical Features

                              • Microscopic Features

                                CLINICAL ISSUES

                                • Presentation

                                  • Demographics

                                    • Natural History & Prognosis

                                      • Treatment

                                        DIAGNOSTIC CHECKLIST

                                        • Consider

                                          • Image Interpretation Pearls

                                            Selected References

                                            1. Haaga TL et al: Benign ovarian serous cystadenoma mimicking papillary thyroid carcinoma metastasis on I-131 SPECT/CT. Med Health R I. 95(2):57-9, 2012
                                            2. Li J et al: Ovarian serous carcinoma: recent concepts on its origin and carcinogenesis. J Hematol Oncol. 5:8, 2012
                                            3. Lalwani N et al: Histologic, molecular, and cytogenetic features of ovarian cancers: implications for diagnosis and treatment. Radiographics. 31(3):625-46, 2011
                                            4. Saunders BA et al: Risk of malignancy in sonographically confirmed septated cystic ovarian tumors. Gynecol Oncol. 118(3):278-82, 2010
                                            5. Diamantopoulou S et al: Serous cystadenoma with massive ovarian edema. A case report and review of the literature. Clin Exp Obstet Gynecol. 36(1):58-61, 2009
                                            6. Dorum A et al: Prevalence and histologic diagnosis of adnexal cysts in postmenopausal women: an autopsy study. Am J Obstet Gynecol. 192(1):48-54, 2005
                                            7. Fenchel S et al: Asymptomatic adnexal masses: correlation of FDG PET and histopathologic findings. Radiology. 223(3):780-8, 2002
                                            8. Jung SE et al: CT and MR imaging of ovarian tumors with emphasis on differential diagnosis. Radiographics. 22(6):1305-25, 2002
                                            9. Jeong YY et al: Imaging evaluation of ovarian masses. Radiographics. 20(5):1445-70, 2000
                                            10. Yamashita Y et al: Adnexal masses: accuracy of characterization with transvaginal US and precontrast and postcontrast MR imaging. Radiology. 194(2):557-65, 1995
                                            11. Kurman RJ et al: The behavior of serous tumors of low malignant potential: are they ever malignant? Int J Gynecol Pathol. 12(2):120-7, 1993
                                            Related Anatomy
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                                            Related Differential Diagnoses
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                                            References
                                            Tables

                                            Tables

                                            KEY FACTS

                                            • Terminology

                                              • Imaging

                                                • Top Differential Diagnoses

                                                  • Clinical Issues

                                                    • Diagnostic Checklist

                                                      TERMINOLOGY

                                                      • Definitions

                                                        • Benign ovarian tumor classified as epithelial ovarian neoplasm
                                                        • Thin-walled, serous fluid-containing cyst(s) lined by single layer of epithelium

                                                      IMAGING

                                                      • General Features

                                                        • CT Findings

                                                          • MR Findings

                                                            • Ultrasonographic Findings

                                                              • Nuclear Medicine Findings

                                                                • Imaging Recommendations

                                                                  DIFFERENTIAL DIAGNOSIS

                                                                    PATHOLOGY

                                                                    • General Features

                                                                      • Gross Pathologic & Surgical Features

                                                                        • Microscopic Features

                                                                          CLINICAL ISSUES

                                                                          • Presentation

                                                                            • Demographics

                                                                              • Natural History & Prognosis

                                                                                • Treatment

                                                                                  DIAGNOSTIC CHECKLIST

                                                                                  • Consider

                                                                                    • Image Interpretation Pearls

                                                                                      Selected References

                                                                                      1. Haaga TL et al: Benign ovarian serous cystadenoma mimicking papillary thyroid carcinoma metastasis on I-131 SPECT/CT. Med Health R I. 95(2):57-9, 2012
                                                                                      2. Li J et al: Ovarian serous carcinoma: recent concepts on its origin and carcinogenesis. J Hematol Oncol. 5:8, 2012
                                                                                      3. Lalwani N et al: Histologic, molecular, and cytogenetic features of ovarian cancers: implications for diagnosis and treatment. Radiographics. 31(3):625-46, 2011
                                                                                      4. Saunders BA et al: Risk of malignancy in sonographically confirmed septated cystic ovarian tumors. Gynecol Oncol. 118(3):278-82, 2010
                                                                                      5. Diamantopoulou S et al: Serous cystadenoma with massive ovarian edema. A case report and review of the literature. Clin Exp Obstet Gynecol. 36(1):58-61, 2009
                                                                                      6. Dorum A et al: Prevalence and histologic diagnosis of adnexal cysts in postmenopausal women: an autopsy study. Am J Obstet Gynecol. 192(1):48-54, 2005
                                                                                      7. Fenchel S et al: Asymptomatic adnexal masses: correlation of FDG PET and histopathologic findings. Radiology. 223(3):780-8, 2002
                                                                                      8. Jung SE et al: CT and MR imaging of ovarian tumors with emphasis on differential diagnosis. Radiographics. 22(6):1305-25, 2002
                                                                                      9. Jeong YY et al: Imaging evaluation of ovarian masses. Radiographics. 20(5):1445-70, 2000
                                                                                      10. Yamashita Y et al: Adnexal masses: accuracy of characterization with transvaginal US and precontrast and postcontrast MR imaging. Radiology. 194(2):557-65, 1995
                                                                                      11. Kurman RJ et al: The behavior of serous tumors of low malignant potential: are they ever malignant? Int J Gynecol Pathol. 12(2):120-7, 1993