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KEY FACTS
Terminology
Imaging
Top Differential Diagnoses
Pathology
Clinical Issues
Diagnostic Checklist
TERMINOLOGY
Abbreviations
- Low-grade serous ovarian cancer (LGSC)
- Serous tubal intraepithelial carcinoma (STIC)
- Epithelial inclusion cyst (EIC)
Definitions
- Serous epithelial neoplasm
- Benign (serous cystadenoma)
- Low malignant potential (borderline serous and LGSC)
- Malignant (high-grade serous ovarian neoplasm)
- Distinct histopathologic entity from benign, borderline serous, and LGSC
- Hence, serous cystadenocarcinoma terminology is going out of favor
- Serous epithelial neoplasm
IMAGING
General Features
Ultrasonographic Findings
CT Findings
MR Findings
Imaging Recommendations
DIFFERENTIAL DIAGNOSIS
PATHOLOGY
General Features
CLINICAL ISSUES
Presentation
Demographics
Natural History & Prognosis
Treatment
DIAGNOSTIC CHECKLIST
Consider
Image Interpretation Pearls
Selected References
- An H et al: CT texture analysis in histological classification of epithelial ovarian carcinoma. Eur Radiol. ePub, 2021
- Basha MAA et al: Comparison of O-RADS, GI-RADS, and IOTA simple rules regarding malignancy rate, validity, and reliability for diagnosis of adnexal masses. Eur Radiol. 31(2):674-84, 2021
- Bourdel N et al: Borderline ovarian tumors: guidelines from the French National College Of Obstetricians and Gynecologists (CNGOF). Eur J Obstet Gynecol Reprod Biol. 256:492-501, 2021
- Reinhold C et al: Ovarian-Adnexal Reporting Lexicon for MRI: a white paper of the ACR Ovarian-Adnexal Reporting and Data Systems MRI Committee. J Am Coll Radiol. ePub, 2021
- Shanbhogue KP et al: Hereditary ovarian tumour syndromes: current update on genetics and imaging. Clin Radiol. 76(4):313.e15-26, 2021
- Taylor EC et al: Multimodality imaging approach to ovarian neoplasms with pathologic correlation. Radiographics. 41(1):289-315, 2021
- Yu XP et al: MDCT-based radiomics features for the differentiation of serous borderline ovarian tumors and serous malignant ovarian tumors. Cancer Manag Res. 13:329-36, 2021
- Chung SH et al: BRCA and beyond: comprehensive image-rich review of hereditary breast and gynecologic cancer syndromes. Radiographics. 40(2):306-25, 2020
- Flicek KT et al: Borderline epithelial ovarian tumors: what the radiologist should know. Abdom Radiol (NY). ePub, 2020
- O'Neill AC et al: Patterns and prognostic importance of hepatic involvement in patients with serous ovarian cancer: a single-institution experience with 244 patients. Radiology. 282(1):160-70, 2017
- Trillsch F et al: Surgical staging and prognosis in serous borderline ovarian tumours (BOT): a subanalysis of the AGO ROBOT study. Br J Cancer. 112(4):660-6, 2015
- Prat J et al: Staging classification for cancer of the ovary, fallopian tube, and peritoneum. Int J Gynaecol Obstet. 124(1):1-5, 2014
- Alcázar JL et al: Clinical and ultrasound features of type I and type II epithelial ovarian cancer. Int J Gynecol Cancer. 23(4):680-4, 2013
- Xie M et al: Application of real-time ultrasound elastography for discrimination of low- and high-grade serous ovarian carcinoma. J Ultrasound Med. 32(2):257-62, 2013
- Barton SE et al: Recurrent bilateral serous cystadenomas in a premenarchal girl: a case report and literature review. J Pediatr Adolesc Gynecol. 23(1):e27-9, 2010
- Diamantopoulou S et al: Serous cystadenoma with massive ovarian edema. A case report and review of the literature. Clin Exp Obstet Gynecol. 36(1):58-61, 2009
- Woodward PJ et al: From the archives of the AFIP: radiologic staging of ovarian carcinoma with pathologic correlation. Radiographics. 24(1):225-46, 2004
- Wagner BJ et al: From the archives of the AFIP. Ovarian epithelial neoplasms: radiologic-pathologic correlation. Radiographics. 14(6):1351-74; quiz 1375-6, 1994
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References
Tables
Tables
KEY FACTS
Terminology
Imaging
Top Differential Diagnoses
Pathology
Clinical Issues
Diagnostic Checklist
TERMINOLOGY
Abbreviations
- Low-grade serous ovarian cancer (LGSC)
- Serous tubal intraepithelial carcinoma (STIC)
- Epithelial inclusion cyst (EIC)
Definitions
- Serous epithelial neoplasm
- Benign (serous cystadenoma)
- Low malignant potential (borderline serous and LGSC)
- Malignant (high-grade serous ovarian neoplasm)
- Distinct histopathologic entity from benign, borderline serous, and LGSC
- Hence, serous cystadenocarcinoma terminology is going out of favor
- Serous epithelial neoplasm
IMAGING
General Features
Ultrasonographic Findings
CT Findings
MR Findings
Imaging Recommendations
DIFFERENTIAL DIAGNOSIS
PATHOLOGY
General Features
CLINICAL ISSUES
Presentation
Demographics
Natural History & Prognosis
Treatment
DIAGNOSTIC CHECKLIST
Consider
Image Interpretation Pearls
Selected References
- An H et al: CT texture analysis in histological classification of epithelial ovarian carcinoma. Eur Radiol. ePub, 2021
- Basha MAA et al: Comparison of O-RADS, GI-RADS, and IOTA simple rules regarding malignancy rate, validity, and reliability for diagnosis of adnexal masses. Eur Radiol. 31(2):674-84, 2021
- Bourdel N et al: Borderline ovarian tumors: guidelines from the French National College Of Obstetricians and Gynecologists (CNGOF). Eur J Obstet Gynecol Reprod Biol. 256:492-501, 2021
- Reinhold C et al: Ovarian-Adnexal Reporting Lexicon for MRI: a white paper of the ACR Ovarian-Adnexal Reporting and Data Systems MRI Committee. J Am Coll Radiol. ePub, 2021
- Shanbhogue KP et al: Hereditary ovarian tumour syndromes: current update on genetics and imaging. Clin Radiol. 76(4):313.e15-26, 2021
- Taylor EC et al: Multimodality imaging approach to ovarian neoplasms with pathologic correlation. Radiographics. 41(1):289-315, 2021
- Yu XP et al: MDCT-based radiomics features for the differentiation of serous borderline ovarian tumors and serous malignant ovarian tumors. Cancer Manag Res. 13:329-36, 2021
- Chung SH et al: BRCA and beyond: comprehensive image-rich review of hereditary breast and gynecologic cancer syndromes. Radiographics. 40(2):306-25, 2020
- Flicek KT et al: Borderline epithelial ovarian tumors: what the radiologist should know. Abdom Radiol (NY). ePub, 2020
- O'Neill AC et al: Patterns and prognostic importance of hepatic involvement in patients with serous ovarian cancer: a single-institution experience with 244 patients. Radiology. 282(1):160-70, 2017
- Trillsch F et al: Surgical staging and prognosis in serous borderline ovarian tumours (BOT): a subanalysis of the AGO ROBOT study. Br J Cancer. 112(4):660-6, 2015
- Prat J et al: Staging classification for cancer of the ovary, fallopian tube, and peritoneum. Int J Gynaecol Obstet. 124(1):1-5, 2014
- Alcázar JL et al: Clinical and ultrasound features of type I and type II epithelial ovarian cancer. Int J Gynecol Cancer. 23(4):680-4, 2013
- Xie M et al: Application of real-time ultrasound elastography for discrimination of low- and high-grade serous ovarian carcinoma. J Ultrasound Med. 32(2):257-62, 2013
- Barton SE et al: Recurrent bilateral serous cystadenomas in a premenarchal girl: a case report and literature review. J Pediatr Adolesc Gynecol. 23(1):e27-9, 2010
- Diamantopoulou S et al: Serous cystadenoma with massive ovarian edema. A case report and review of the literature. Clin Exp Obstet Gynecol. 36(1):58-61, 2009
- Woodward PJ et al: From the archives of the AFIP: radiologic staging of ovarian carcinoma with pathologic correlation. Radiographics. 24(1):225-46, 2004
- Wagner BJ et al: From the archives of the AFIP. Ovarian epithelial neoplasms: radiologic-pathologic correlation. Radiographics. 14(6):1351-74; quiz 1375-6, 1994
