Inoue K et al: Pazopanib treatment of a platinum-resistant recurrence of a high-grade Sertoli cell tumor and assessment of the treatment response by FDG-PET/CT: a case report. Gynecol Oncol Rep. 24:54-6, 2018
Horta M et al: Sex cord-stromal tumors of the ovary: a comprehensive review and update for radiologists. Diagn Interv Radiol. 21(4):277-86, 2015
Cai SQ et al: Ovarian Sertoli-Leydig cell tumors: MRI findings and pathological correlation. J Ovarian Res. 6(1):73, 2013
Prassopoulos V et al: Leydig cell tumour of the ovary localised with positron emission tomography/computed tomography. Gynecol Endocrinol. 27(10):837-9, 2011
Rio Frio T et al: DICER1 mutations in familial multinodular goiter with and without ovarian Sertoli-Leydig cell tumors. JAMA. 305(1):68-77, 2011
Ozülker T et al: Incidental detection of Sertoli-Leydig cell tumor by FDG PET/CT imaging in a patient with androgen insensitivity syndrome. Ann Nucl Med. 24(1):35-9, 2010
Shanbhogue AK et al: Clinical syndromes associated with ovarian neoplasms: a comprehensive review. Radiographics. 30(4):903-19, 2010
Azuma A et al: A case of Sertoli-Leydig cell tumour of the ovary with a multilocular cystic appearance on CT and MR imaging. Pediatr Radiol. 38(8):898-901, 2008
Demidov VN et al: Imaging of gynecological disease (2): clinical and ultrasound characteristics of Sertoli cell tumors, Sertoli-Leydig cell tumors and Leydig cell tumors. Ultrasound Obstet Gynecol. 31(1):85-91, 2008
Caringella A et al: A case of Sertoli-Leydig cell tumor in a postmenopausal woman. Int J Gynecol Cancer. 16(1):435-8, 2006
Roth LM: Recent advances in the pathology and classification of ovarian sex cord-stromal tumors. Int J Gynecol Pathol. 25(3):199-215, 2006
Elbadrawy M et al: Secondary amenorrhoea due to Leydig cell tumour. J Obstet Gynaecol. 25(5):529-30, 2005
Jung SE et al: CT and MRI findings of sex cord-stromal tumor of the ovary. AJR Am J Roentgenol. 185(1):207-15, 2005
Oliva E et al: Sertoli cell tumors of the ovary: a clinicopathologic and immunohistochemical study of 54 cases. Am J Surg Pathol. 29(2):143-56, 2005
Appetecchia M et al: Sertoli-Leydig cell androgens-estrogens secreting tumor of the ovary: ultra-conservative surgery. Eur J Obstet Gynecol Reprod Biol. 116(1):113-6, 2004
Tanaka YO et al: Functioning ovarian tumors: direct and indirect findings at MR imaging. Radiographics. 24 Suppl 1:S147-66, 2004
Jung SE et al: CT and MR imaging of ovarian tumors with emphasis on differential diagnosis. Radiographics. 22(6):1305-25, 2002
Lantzsch T et al: Sertoli-Leydig cell tumor. Arch Gynecol Obstet. 264(4):206-8, 2001
Related Anatomy
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Related Differential Diagnoses
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References
Tables
Tables
KEY FACTS
Terminology
Imaging
Top Differential Diagnoses
Pathology
Clinical Issues
TERMINOLOGY
Definitions
Ovarian sex cord-stromal tumors
Sertoli cell tumors (SCTs)
Sertoli-Leydig cell tumors (SLCTs)
IMAGING
General Features
CT Findings
MR Findings
Ultrasonographic Findings
PET/CT
Imaging Recommendations
DIFFERENTIAL DIAGNOSIS
PATHOLOGY
General Features
Staging, Grading, & Classification
Gross Pathologic & Surgical Features
Microscopic Features
CLINICAL ISSUES
Presentation
Demographics
Natural History & Prognosis
Treatment
DIAGNOSTIC CHECKLIST
Consider
Image Interpretation Pearls
Selected References
Inoue K et al: Pazopanib treatment of a platinum-resistant recurrence of a high-grade Sertoli cell tumor and assessment of the treatment response by FDG-PET/CT: a case report. Gynecol Oncol Rep. 24:54-6, 2018
Horta M et al: Sex cord-stromal tumors of the ovary: a comprehensive review and update for radiologists. Diagn Interv Radiol. 21(4):277-86, 2015
Cai SQ et al: Ovarian Sertoli-Leydig cell tumors: MRI findings and pathological correlation. J Ovarian Res. 6(1):73, 2013
Prassopoulos V et al: Leydig cell tumour of the ovary localised with positron emission tomography/computed tomography. Gynecol Endocrinol. 27(10):837-9, 2011
Rio Frio T et al: DICER1 mutations in familial multinodular goiter with and without ovarian Sertoli-Leydig cell tumors. JAMA. 305(1):68-77, 2011
Ozülker T et al: Incidental detection of Sertoli-Leydig cell tumor by FDG PET/CT imaging in a patient with androgen insensitivity syndrome. Ann Nucl Med. 24(1):35-9, 2010
Shanbhogue AK et al: Clinical syndromes associated with ovarian neoplasms: a comprehensive review. Radiographics. 30(4):903-19, 2010
Azuma A et al: A case of Sertoli-Leydig cell tumour of the ovary with a multilocular cystic appearance on CT and MR imaging. Pediatr Radiol. 38(8):898-901, 2008
Demidov VN et al: Imaging of gynecological disease (2): clinical and ultrasound characteristics of Sertoli cell tumors, Sertoli-Leydig cell tumors and Leydig cell tumors. Ultrasound Obstet Gynecol. 31(1):85-91, 2008
Caringella A et al: A case of Sertoli-Leydig cell tumor in a postmenopausal woman. Int J Gynecol Cancer. 16(1):435-8, 2006
Roth LM: Recent advances in the pathology and classification of ovarian sex cord-stromal tumors. Int J Gynecol Pathol. 25(3):199-215, 2006
Elbadrawy M et al: Secondary amenorrhoea due to Leydig cell tumour. J Obstet Gynaecol. 25(5):529-30, 2005
Jung SE et al: CT and MRI findings of sex cord-stromal tumor of the ovary. AJR Am J Roentgenol. 185(1):207-15, 2005
Oliva E et al: Sertoli cell tumors of the ovary: a clinicopathologic and immunohistochemical study of 54 cases. Am J Surg Pathol. 29(2):143-56, 2005
Appetecchia M et al: Sertoli-Leydig cell androgens-estrogens secreting tumor of the ovary: ultra-conservative surgery. Eur J Obstet Gynecol Reprod Biol. 116(1):113-6, 2004
Tanaka YO et al: Functioning ovarian tumors: direct and indirect findings at MR imaging. Radiographics. 24 Suppl 1:S147-66, 2004
Jung SE et al: CT and MR imaging of ovarian tumors with emphasis on differential diagnosis. Radiographics. 22(6):1305-25, 2002
Lantzsch T et al: Sertoli-Leydig cell tumor. Arch Gynecol Obstet. 264(4):206-8, 2001
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