Group of ovarian tumors arising from either embryonic sex cords or mesenchyme
Fibroma, thecoma, fibrothecoma
Granulosa cell tumor: Occurs in both adult and juvenile forms
Sertoli-Leydig tumor (androblastoma)
Sclerosing stromal tumor, steroid cell tumors, gynandroblastoma, and sex cord tumor with annular tubules
IMAGING
General Features
Ultrasonographic Findings
MR Findings
Imaging Recommendations
DIFFERENTIAL DIAGNOSIS
PATHOLOGY
General Features
Microscopic Features
CLINICAL ISSUES
Presentation
Demographics
Natural History & Prognosis
DIAGNOSTIC CHECKLIST
Consider
Image Interpretation Pearls
Selected References
Elsherif S et al: Multimodality imaging and genomics of granulosa cell tumors. Abdom Radiol (NY). 45(3):812-27, 2020
Young RH: Ovarian sex cord-stromal tumours and their mimics. Pathology. 50(1):5-15, 2018
Hogan ME et al: Ovarian fibroma presenting with Meigs syndrome. Ultrasound Q. 31(3):215-8, 2015
Heo SH et al: Review of ovarian tumors in children and adolescents: radiologic-pathologic correlation. Radiographics. 34(7):2039-55, 2014
Singh AK et al: Gorlin syndrome. J Pediatr. 164(6):1501-e1, 2014
Sekkate S et al: Ovarian granulosa cell tumors: a retrospective study of 27 cases and a review of the literature. World J Surg Oncol. 11:142, 2013
Yen P et al: Ovarian fibromas and fibrothecomas: sonographic correlation with computed tomography and magnetic resonance imaging: a 5-year single-institution experience. J Ultrasound Med. 32(1):13-8, 2013
Alcázar JL et al: Clinical and sonographic features of uncommon primary ovarian malignancies. J Clin Ultrasound. 40(6):323-9, 2012
Chung EM et al: From the radiologic pathology archives: precocious puberty: radiologic-pathologic correlation. Radiographics. 32(7):2071-99, 2012
Shinagare AB et al: MRI features of ovarian fibroma and fibrothecoma with histopathologic correlation. AJR Am J Roentgenol. 198(3):W296-303, 2012
Kim JA et al: High-resolution sonographic findings of ovarian granulosa cell tumors: correlation with pathologic findings. J Ultrasound Med. 29(2):187-93, 2010
Shanbhogue AK et al: Clinical syndromes associated with ovarian neoplasms: a comprehensive review. Radiographics. 30(4):903-19, 2010
Demidov VN et al: Imaging of gynecological disease (2): clinical and ultrasound characteristics of Sertoli cell tumors, Sertoli-Leydig cell tumors and Leydig cell tumors. Ultrasound Obstet Gynecol. 31(1):85-91, 2008
Van Holsbeke C et al: Imaging of gynecological disease (3): clinical and ultrasound characteristics of granulosa cell tumors of the ovary. Ultrasound Obstet Gynecol. 31(4):450-6, 2008
Tanaka YO et al: Functioning ovarian tumors: direct and indirect findings at MR imaging. Radiographics. 24 Suppl 1:S147-66, 2004
Kim SH et al: Granulosa cell tumor of the ovary: common findings and unusual appearances on CT and MR. J Comput Assist Tomogr. 26(5):756-61, 2002
Outwater EK et al: Virilizing tumors of the ovary: imaging features. Ultrasound Obstet Gynecol. 15(5):365-71, 2000
Outwater EK et al: Sex cord-stromal and steroid cell tumors of the ovary. Radiographics. 18(6):1523-46, 1998
Malmstrom H et al: Granulosa cell tumors of the ovary: prognostic factors and outcome. Gynecol Oncol. 52(1):50-5, 1994
Related Anatomy
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Related Differential Diagnoses
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References
Tables
Tables
KEY FACTS
Terminology
Imaging
Top Differential Diagnoses
Clinical Issues
TERMINOLOGY
Definitions
Group of ovarian tumors arising from either embryonic sex cords or mesenchyme
Fibroma, thecoma, fibrothecoma
Granulosa cell tumor: Occurs in both adult and juvenile forms
Sertoli-Leydig tumor (androblastoma)
Sclerosing stromal tumor, steroid cell tumors, gynandroblastoma, and sex cord tumor with annular tubules
IMAGING
General Features
Ultrasonographic Findings
MR Findings
Imaging Recommendations
DIFFERENTIAL DIAGNOSIS
PATHOLOGY
General Features
Microscopic Features
CLINICAL ISSUES
Presentation
Demographics
Natural History & Prognosis
DIAGNOSTIC CHECKLIST
Consider
Image Interpretation Pearls
Selected References
Elsherif S et al: Multimodality imaging and genomics of granulosa cell tumors. Abdom Radiol (NY). 45(3):812-27, 2020
Young RH: Ovarian sex cord-stromal tumours and their mimics. Pathology. 50(1):5-15, 2018
Hogan ME et al: Ovarian fibroma presenting with Meigs syndrome. Ultrasound Q. 31(3):215-8, 2015
Heo SH et al: Review of ovarian tumors in children and adolescents: radiologic-pathologic correlation. Radiographics. 34(7):2039-55, 2014
Singh AK et al: Gorlin syndrome. J Pediatr. 164(6):1501-e1, 2014
Sekkate S et al: Ovarian granulosa cell tumors: a retrospective study of 27 cases and a review of the literature. World J Surg Oncol. 11:142, 2013
Yen P et al: Ovarian fibromas and fibrothecomas: sonographic correlation with computed tomography and magnetic resonance imaging: a 5-year single-institution experience. J Ultrasound Med. 32(1):13-8, 2013
Alcázar JL et al: Clinical and sonographic features of uncommon primary ovarian malignancies. J Clin Ultrasound. 40(6):323-9, 2012
Chung EM et al: From the radiologic pathology archives: precocious puberty: radiologic-pathologic correlation. Radiographics. 32(7):2071-99, 2012
Shinagare AB et al: MRI features of ovarian fibroma and fibrothecoma with histopathologic correlation. AJR Am J Roentgenol. 198(3):W296-303, 2012
Kim JA et al: High-resolution sonographic findings of ovarian granulosa cell tumors: correlation with pathologic findings. J Ultrasound Med. 29(2):187-93, 2010
Shanbhogue AK et al: Clinical syndromes associated with ovarian neoplasms: a comprehensive review. Radiographics. 30(4):903-19, 2010
Demidov VN et al: Imaging of gynecological disease (2): clinical and ultrasound characteristics of Sertoli cell tumors, Sertoli-Leydig cell tumors and Leydig cell tumors. Ultrasound Obstet Gynecol. 31(1):85-91, 2008
Van Holsbeke C et al: Imaging of gynecological disease (3): clinical and ultrasound characteristics of granulosa cell tumors of the ovary. Ultrasound Obstet Gynecol. 31(4):450-6, 2008
Tanaka YO et al: Functioning ovarian tumors: direct and indirect findings at MR imaging. Radiographics. 24 Suppl 1:S147-66, 2004
Kim SH et al: Granulosa cell tumor of the ovary: common findings and unusual appearances on CT and MR. J Comput Assist Tomogr. 26(5):756-61, 2002
Outwater EK et al: Virilizing tumors of the ovary: imaging features. Ultrasound Obstet Gynecol. 15(5):365-71, 2000
Outwater EK et al: Sex cord-stromal and steroid cell tumors of the ovary. Radiographics. 18(6):1523-46, 1998
Malmstrom H et al: Granulosa cell tumors of the ovary: prognostic factors and outcome. Gynecol Oncol. 52(1):50-5, 1994
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