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KEY FACTS
Terminology
Imaging
Top Differential Diagnoses
Pathology
Clinical Issues
Diagnostic Checklist
TERMINOLOGY
Abbreviations
- Sickle cell disease (Hb SS)
- Acute chest syndrome (ACS)
Definitions
- Sickle cell disease: Abnormal hemoglobin that deforms when deoxygenated
- Acute chest syndrome: Noninfectious vasoocclusive crisis in patients with Hb SS associated with chest radiographic abnormalities
- Initiated by lung infection or infarction
- Sickle cell chronic lung disease: Result of recurrent acute chest syndrome
IMAGING
General Features
Radiographic Findings
CT Findings
Nuclear Medicine Findings
Imaging Recommendations
DIFFERENTIAL DIAGNOSIS
PATHOLOGY
General Features
Microscopic Features
CLINICAL ISSUES
Presentation
Demographics
Natural History & Prognosis
Treatment
DIAGNOSTIC CHECKLIST
Consider
Selected References
- Gladwin MT et al: Pulmonary complications of sickle cell disease. N Engl J Med. 359(21):2254-65, 2008
- Delclaux C et al: Factors associated with dyspnea in adult patients with sickle cell disease. Chest. 128(5):3336-44, 2005
- Maitre B et al: Acute chest syndrome in adults with sickle cell disease. Chest. 117(5):1386-92, 2000
Related Anatomy
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Related Differential Diagnoses
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References
Tables
Tables
KEY FACTS
Terminology
Imaging
Top Differential Diagnoses
Pathology
Clinical Issues
Diagnostic Checklist
TERMINOLOGY
Abbreviations
- Sickle cell disease (Hb SS)
- Acute chest syndrome (ACS)
Definitions
- Sickle cell disease: Abnormal hemoglobin that deforms when deoxygenated
- Acute chest syndrome: Noninfectious vasoocclusive crisis in patients with Hb SS associated with chest radiographic abnormalities
- Initiated by lung infection or infarction
- Sickle cell chronic lung disease: Result of recurrent acute chest syndrome
IMAGING
General Features
Radiographic Findings
CT Findings
Nuclear Medicine Findings
Imaging Recommendations
DIFFERENTIAL DIAGNOSIS
PATHOLOGY
General Features
Microscopic Features
CLINICAL ISSUES
Presentation
Demographics
Natural History & Prognosis
Treatment
DIAGNOSTIC CHECKLIST
Consider
Selected References
- Gladwin MT et al: Pulmonary complications of sickle cell disease. N Engl J Med. 359(21):2254-65, 2008
- Delclaux C et al: Factors associated with dyspnea in adult patients with sickle cell disease. Chest. 128(5):3336-44, 2005
- Maitre B et al: Acute chest syndrome in adults with sickle cell disease. Chest. 117(5):1386-92, 2000
