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KEY FACTS
Terminology
Imaging
TERMINOLOGY
Abbreviations
- Sickle cell anemia (SCA)
Definitions
- Inherited hemolytic anemia arising due to abnormal hemoglobin (hemoglobin S), resulting in deformation of red blood cells and leading to microvascular occlusions and infarcts
IMAGING
General Features
CT Findings
MR Findings
Ultrasonographic Findings
Radiographic Findings
Imaging Recommendations
DIFFERENTIAL DIAGNOSIS
PATHOLOGY
General Features
Staging, Grading, & Classification
Gross Pathologic & Surgical Features
Microscopic Features
CLINICAL ISSUES
Presentation
Demographics
Natural History & Prognosis
Treatment
DIAGNOSTIC CHECKLIST
Consider
Selected References
- Kinger NP et al: Abdominal manifestations of sickle cell disease. Curr Probl Diagn Radiol. 50(2):241-51, 2020
- Riminucci M et al: Re: Renal medullary carcinoma and its association with sickle cell trait: a case report and literature review. Curr Oncol. 27(3):e348, 2020
- Orphanidou-Vlachou E et al: Extramedullary hemopoiesis. Semin Ultrasound CT MR. 35(3):255-62, 2014
- Al-Salem AH: Massive splenic infarction in children with sickle cell anemia and the role of splenectomy. Pediatr Surg Int. 29(3):281-5, 2013
- Raman SP et al: Beyond renal cell carcinoma: rare and unusual renal masses. Abdom Imaging. 37(5):873-84, 2012
- Al-Salem AH: Splenic complications of sickle cell anemia and the role of splenectomy. ISRN Hematol. 2011:864257, 2011
- Brewer CJ et al: Spleen R2 and R2* in iron-overloaded patients with sickle cell disease and thalassemia major. J Magn Reson Imaging. 29(2):357-64, 2009
- Khatib R et al: The spleen in the sickling disorders: an update. Pediatr Radiol. 39(1):17-22, 2009
- Balci A et al: Prevalence of abdominal ultrasonographic abnormalities in patients with sickle cell disease. Diagn Interv Radiol. 14(3):133-7, 2008
- Mestre-Fusco A et al: Sickle cell anemia and functioning splenic tissue: correlation of scintigraphic findings and CT. Clin Nucl Med. 33(2):137-9, 2008
- Papadaki MG et al: Abdominal ultrasonographic findings in patients with sickle-cell anaemia and thalassaemia intermedia. Pediatr Radiol. 33(8):515-21, 2003
- Lonergan GJ et al: Sickle cell anemia. Radiographics. 21(4):971-94, 2001
- Sheth S et al: CT imaging of splenic sequestration in sickle cell disease. Pediatr Radiol. 30(12):830-3, 2000
- Siegelman ES et al: Abdominal iron distribution in sickle cell disease: MR findings in transfusion and nontransfusion dependent patients. J Comput Assist Tomogr. 18(1):63-7, 1994
- D'Alonzo WA Jr et al: Biliary scintigraphy in children with sickle cell anemia and acute abdominal pain. Pediatr Radiol. 15(6):395-8, 1985
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References
Tables
Tables
KEY FACTS
Terminology
Imaging
TERMINOLOGY
Abbreviations
- Sickle cell anemia (SCA)
Definitions
- Inherited hemolytic anemia arising due to abnormal hemoglobin (hemoglobin S), resulting in deformation of red blood cells and leading to microvascular occlusions and infarcts
IMAGING
General Features
CT Findings
MR Findings
Ultrasonographic Findings
Radiographic Findings
Imaging Recommendations
DIFFERENTIAL DIAGNOSIS
PATHOLOGY
General Features
Staging, Grading, & Classification
Gross Pathologic & Surgical Features
Microscopic Features
CLINICAL ISSUES
Presentation
Demographics
Natural History & Prognosis
Treatment
DIAGNOSTIC CHECKLIST
Consider
Selected References
- Kinger NP et al: Abdominal manifestations of sickle cell disease. Curr Probl Diagn Radiol. 50(2):241-51, 2020
- Riminucci M et al: Re: Renal medullary carcinoma and its association with sickle cell trait: a case report and literature review. Curr Oncol. 27(3):e348, 2020
- Orphanidou-Vlachou E et al: Extramedullary hemopoiesis. Semin Ultrasound CT MR. 35(3):255-62, 2014
- Al-Salem AH: Massive splenic infarction in children with sickle cell anemia and the role of splenectomy. Pediatr Surg Int. 29(3):281-5, 2013
- Raman SP et al: Beyond renal cell carcinoma: rare and unusual renal masses. Abdom Imaging. 37(5):873-84, 2012
- Al-Salem AH: Splenic complications of sickle cell anemia and the role of splenectomy. ISRN Hematol. 2011:864257, 2011
- Brewer CJ et al: Spleen R2 and R2* in iron-overloaded patients with sickle cell disease and thalassemia major. J Magn Reson Imaging. 29(2):357-64, 2009
- Khatib R et al: The spleen in the sickling disorders: an update. Pediatr Radiol. 39(1):17-22, 2009
- Balci A et al: Prevalence of abdominal ultrasonographic abnormalities in patients with sickle cell disease. Diagn Interv Radiol. 14(3):133-7, 2008
- Mestre-Fusco A et al: Sickle cell anemia and functioning splenic tissue: correlation of scintigraphic findings and CT. Clin Nucl Med. 33(2):137-9, 2008
- Papadaki MG et al: Abdominal ultrasonographic findings in patients with sickle-cell anaemia and thalassaemia intermedia. Pediatr Radiol. 33(8):515-21, 2003
- Lonergan GJ et al: Sickle cell anemia. Radiographics. 21(4):971-94, 2001
- Sheth S et al: CT imaging of splenic sequestration in sickle cell disease. Pediatr Radiol. 30(12):830-3, 2000
- Siegelman ES et al: Abdominal iron distribution in sickle cell disease: MR findings in transfusion and nontransfusion dependent patients. J Comput Assist Tomogr. 18(1):63-7, 1994
- D'Alonzo WA Jr et al: Biliary scintigraphy in children with sickle cell anemia and acute abdominal pain. Pediatr Radiol. 15(6):395-8, 1985
