Melissa Durand, MD; Wendie A. Berg, MD, PhD, FACR, FSBI
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KEY FACTS
Terminology
Imaging
Pathology
Clinical Issues
TERMINOLOGY
Abbreviations
Silicone-induced granuloma of breast implant capsule (SIGBIC) due to gel bleed from intact implant
Definitions
Silicone granuloma = siliconoma: Inflammatory mass caused by foreign body reaction to silicone gel in tissue; result of extracapsular rupture, gel bleed, or free injection
IMAGING
General Features
Mammographic Findings
Ultrasonographic Findings
Nuclear Medicine Findings
MR Findings
Imaging Recommendations
DIFFERENTIAL DIAGNOSIS
PATHOLOGY
Microscopic Features
CLINICAL ISSUES
Presentation
Natural History & Prognosis
Treatment
DIAGNOSTIC CHECKLIST
Consider
Image Interpretation Pearls
Selected References
Seynnaeve C and Berg WA: Intraductal extracapsular rupture of silicone breast implant. Annals Clin Case Reports. 2:1369-70, 2017
de Faria Castro Fleury E et al: Breast magnetic resonance imaging: tips for the diagnosis of silicone-induced granuloma of a breast implant capsule (SIGBIC). Insights Imaging. 8(4):439-446, 2017
Seiler SJ et al: Multimodality imaging-based evaluation of single-lumen silicone breast implants for rupture. Radiographics. 37(2):366-382, 2017
Zambacos GJ et al: Silicone lymphadenopathy after breast augmentation: case reports, review of the literature, and current thoughts. Aesthetic Plast Surg. 37(2):278-89, 2013
DiCarlo CM et al: Pleural silicone granuloma mimics pleural metastasis: Ruptured breast implant with silicone fistulising along a remote thoracotomy scar. Radiol Case Rep. 7(3):672, 2012
Shepherd SM et al: Silicone granuloma mimicking breast cancer recurrence on PET CT. Breast J. 16(5):551-3, 2010
Berg WA et al: MR imaging of extracapsular silicone from breast implants: diagnostic pitfalls. AJR Am J Roentgenol. 178(2):465-72, 2002
Brown SL et al: Silicone gel breast implant rupture, extracapsular silicone, and health status in a population of women. J Rheumatol. 28(5):996-1003, 2001
Caskey CI et al: Imaging spectrum of extracapsular silicone: correlation of US, MR imaging, mammographic, and histopathologic findings. Radiographics. 19 Spec No:S39-51; quiz S261-2, 1999
Kulber DA et al: Monitoring the axilla in patients with silicone gel implants. Ann Plast Surg. 35(6):580-4, 1995
Harris KM et al: Silicone implant rupture: detection with US. Radiology. 187(3):761-8, 1993
Related Anatomy
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Related Differential Diagnoses
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References
Tables
Tables
KEY FACTS
Terminology
Imaging
Pathology
Clinical Issues
TERMINOLOGY
Abbreviations
Silicone-induced granuloma of breast implant capsule (SIGBIC) due to gel bleed from intact implant
Definitions
Silicone granuloma = siliconoma: Inflammatory mass caused by foreign body reaction to silicone gel in tissue; result of extracapsular rupture, gel bleed, or free injection
IMAGING
General Features
Mammographic Findings
Ultrasonographic Findings
Nuclear Medicine Findings
MR Findings
Imaging Recommendations
DIFFERENTIAL DIAGNOSIS
PATHOLOGY
Microscopic Features
CLINICAL ISSUES
Presentation
Natural History & Prognosis
Treatment
DIAGNOSTIC CHECKLIST
Consider
Image Interpretation Pearls
Selected References
Seynnaeve C and Berg WA: Intraductal extracapsular rupture of silicone breast implant. Annals Clin Case Reports. 2:1369-70, 2017
de Faria Castro Fleury E et al: Breast magnetic resonance imaging: tips for the diagnosis of silicone-induced granuloma of a breast implant capsule (SIGBIC). Insights Imaging. 8(4):439-446, 2017
Seiler SJ et al: Multimodality imaging-based evaluation of single-lumen silicone breast implants for rupture. Radiographics. 37(2):366-382, 2017
Zambacos GJ et al: Silicone lymphadenopathy after breast augmentation: case reports, review of the literature, and current thoughts. Aesthetic Plast Surg. 37(2):278-89, 2013
DiCarlo CM et al: Pleural silicone granuloma mimics pleural metastasis: Ruptured breast implant with silicone fistulising along a remote thoracotomy scar. Radiol Case Rep. 7(3):672, 2012
Shepherd SM et al: Silicone granuloma mimicking breast cancer recurrence on PET CT. Breast J. 16(5):551-3, 2010
Berg WA et al: MR imaging of extracapsular silicone from breast implants: diagnostic pitfalls. AJR Am J Roentgenol. 178(2):465-72, 2002
Brown SL et al: Silicone gel breast implant rupture, extracapsular silicone, and health status in a population of women. J Rheumatol. 28(5):996-1003, 2001
Caskey CI et al: Imaging spectrum of extracapsular silicone: correlation of US, MR imaging, mammographic, and histopathologic findings. Radiographics. 19 Spec No:S39-51; quiz S261-2, 1999
Kulber DA et al: Monitoring the axilla in patients with silicone gel implants. Ann Plast Surg. 35(6):580-4, 1995
Harris KM et al: Silicone implant rupture: detection with US. Radiology. 187(3):761-8, 1993
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