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Silicosis and Coal Worker's Pneumoconiosis
Brett W. Carter, MD, CPPS; Julia Alegría, MD
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KEY FACTS

  • Terminology

    • Imaging

      • Top Differential Diagnoses

        • Clinical Issues

          • Diagnostic Checklist

            TERMINOLOGY

            • Abbreviations

              • Coal worker's pneumoconiosis (CWP)
            • Synonyms

              • Simple pneumoconiosis, complicated pneumoconiosis, progressive massive fibrosis (PMF), anthracosis, anthracosilicosis
            • Definitions

              • Silicosis and CWP: Lung diseases due to inhalation of crystalline silicon dioxide or silica and inorganic mineral dusts
              • Simple or chronic pneumoconiosis: Lung nodules < 1 cm, profuse in upper lung zones, often with hilar/mediastinal lymphadenopathy
              • Complicated pneumoconiosis (PMF): Coalescence of nodules into larger lesions > 1 cm
              • Acute silicoproteinosis: Resembles alveolar proteinosis, develops within weeks after heavy dust exposure
              • Caplan syndrome: CWP + rheumatoid arthritis + necrobiotic nodules
              • Chronic interstitial pneumonia: Pulmonary fibrosis

            IMAGING

            • General Features

              • Radiographic Findings

                • CT Findings

                  • Nuclear Medicine Findings

                    • Imaging Recommendations

                      DIFFERENTIAL DIAGNOSIS

                        PATHOLOGY

                        • General Features

                          • Gross Pathologic & Surgical Features

                            • Microscopic Features

                              CLINICAL ISSUES

                              • Presentation

                                • Demographics

                                  • Natural History & Prognosis

                                    • Treatment

                                      DIAGNOSTIC CHECKLIST

                                      • Consider

                                        Selected References

                                        1. Hoy RF: Artificial stone silicosis. Curr Opin Allergy Clin Immunol. 21(2):114-20, 2021
                                        2. Jones CM et al: Silicosis in artificial stone workers: spectrum of radiological high-resolution CT chest findings. J Med Imaging Radiat Oncol. 64(2):241-9, 2020
                                        3. Expert Panel on Thoracic Imaging et al: ACR appropriateness criteria review ACR appropriateness criteria® occupational lung diseases. J Thorac Imaging. 31(1):W1-3, 2016
                                        4. Chung SY et al: 18F-FDG PET imaging of progressive massive fibrosis. Ann Nucl Med. 24(1):21-7, 2010
                                        5. Sirajuddin A et al: Occupational lung disease. J Thorac Imaging. 24(4):310-20, 2009
                                        6. Arakawa H et al: Chronic interstitial pneumonia in silicosis and mix-dust pneumoconiosis: its prevalence and comparison of CT findings with idiopathic pulmonary fibrosis. Chest. 131(6):1870-6, 2007
                                        7. Chong S et al: Pneumoconiosis: comparison of imaging and pathologic findings. Radiographics. 26(1):59-77, 2006
                                        8. Remy-Jardin M et al: Computed tomographic evaluation of silicosis and coal workers' pneumoconiosis. Radiol Clin North Am. 30(6):1155-76, 1992
                                        9. Remy-Jardin M et al: Coal worker's pneumoconiosis: CT assessment in exposed workers and correlation with radiographic findings. Radiology. 177(2):363-71, 1990
                                        10. Bergin CJ et al: CT in silicosis: correlation with plain films and pulmonary function tests. AJR Am J Roentgenol. 146(3):477-83, 1986
                                        Related Anatomy
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                                        Related Differential Diagnoses
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                                        References
                                        Tables

                                        Tables

                                        KEY FACTS

                                        • Terminology

                                          • Imaging

                                            • Top Differential Diagnoses

                                              • Clinical Issues

                                                • Diagnostic Checklist

                                                  TERMINOLOGY

                                                  • Abbreviations

                                                    • Coal worker's pneumoconiosis (CWP)
                                                  • Synonyms

                                                    • Simple pneumoconiosis, complicated pneumoconiosis, progressive massive fibrosis (PMF), anthracosis, anthracosilicosis
                                                  • Definitions

                                                    • Silicosis and CWP: Lung diseases due to inhalation of crystalline silicon dioxide or silica and inorganic mineral dusts
                                                    • Simple or chronic pneumoconiosis: Lung nodules < 1 cm, profuse in upper lung zones, often with hilar/mediastinal lymphadenopathy
                                                    • Complicated pneumoconiosis (PMF): Coalescence of nodules into larger lesions > 1 cm
                                                    • Acute silicoproteinosis: Resembles alveolar proteinosis, develops within weeks after heavy dust exposure
                                                    • Caplan syndrome: CWP + rheumatoid arthritis + necrobiotic nodules
                                                    • Chronic interstitial pneumonia: Pulmonary fibrosis

                                                  IMAGING

                                                  • General Features

                                                    • Radiographic Findings

                                                      • CT Findings

                                                        • Nuclear Medicine Findings

                                                          • Imaging Recommendations

                                                            DIFFERENTIAL DIAGNOSIS

                                                              PATHOLOGY

                                                              • General Features

                                                                • Gross Pathologic & Surgical Features

                                                                  • Microscopic Features

                                                                    CLINICAL ISSUES

                                                                    • Presentation

                                                                      • Demographics

                                                                        • Natural History & Prognosis

                                                                          • Treatment

                                                                            DIAGNOSTIC CHECKLIST

                                                                            • Consider

                                                                              Selected References

                                                                              1. Hoy RF: Artificial stone silicosis. Curr Opin Allergy Clin Immunol. 21(2):114-20, 2021
                                                                              2. Jones CM et al: Silicosis in artificial stone workers: spectrum of radiological high-resolution CT chest findings. J Med Imaging Radiat Oncol. 64(2):241-9, 2020
                                                                              3. Expert Panel on Thoracic Imaging et al: ACR appropriateness criteria review ACR appropriateness criteria® occupational lung diseases. J Thorac Imaging. 31(1):W1-3, 2016
                                                                              4. Chung SY et al: 18F-FDG PET imaging of progressive massive fibrosis. Ann Nucl Med. 24(1):21-7, 2010
                                                                              5. Sirajuddin A et al: Occupational lung disease. J Thorac Imaging. 24(4):310-20, 2009
                                                                              6. Arakawa H et al: Chronic interstitial pneumonia in silicosis and mix-dust pneumoconiosis: its prevalence and comparison of CT findings with idiopathic pulmonary fibrosis. Chest. 131(6):1870-6, 2007
                                                                              7. Chong S et al: Pneumoconiosis: comparison of imaging and pathologic findings. Radiographics. 26(1):59-77, 2006
                                                                              8. Remy-Jardin M et al: Computed tomographic evaluation of silicosis and coal workers' pneumoconiosis. Radiol Clin North Am. 30(6):1155-76, 1992
                                                                              9. Remy-Jardin M et al: Coal worker's pneumoconiosis: CT assessment in exposed workers and correlation with radiographic findings. Radiology. 177(2):363-71, 1990
                                                                              10. Bergin CJ et al: CT in silicosis: correlation with plain films and pulmonary function tests. AJR Am J Roentgenol. 146(3):477-83, 1986