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Chest
Diagnosis
Interstitial, Diffuse, and Inhalational Lung Disease
Pneumoconiosis
Silo-Filler's Disease
Silo-Filler's Disease
Tyler H. Ternes, MD
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KEY FACTS
Terminology
Imaging
Top Differential Diagnoses
Clinical Issues
Diagnostic Checklist
TERMINOLOGY
Abbreviations
Nitrogen dioxide (NO₂)
Definitions
Occupational lung disease resulting from exposure to NO₂
Inhalation of toxic gases from freshly stored silage
Similar gases: Welding, glassblowing, Zamboni ice resurfacing, manufacturing (lacquers, dyes, rocket propellants, fertilizers), metal cleaning, rayon and food bleaching, nitrocellulose incineration
IMAGING
General Features
Radiographic Findings
CT Findings
Nuclear Medicine Findings
Imaging Recommendations
DIFFERENTIAL DIAGNOSIS
PATHOLOGY
General Features
Microscopic Features
CLINICAL ISSUES
Presentation
Demographics
Natural History & Prognosis
Treatment
DIAGNOSTIC CHECKLIST
Consider
Selected References
Amaducci A et al: Nitrogen Dioxide Toxicity 2021
Amaza IP et al: Silo-filler's disease: one health system's experience and an update of the literature. J Agromedicine. 25(1):8-13, 2020
Leavey JF et al: Silo-filler's disease, the acute respiratory distress syndrome, and oxides of nitrogen. Ann Intern Med. 141(5):410-1, 2004
Jackson L: Grain silo cleanup operation leads to two occupational deaths. Appl Occup Environ Hyg. 17(7):464-6, 2002
Stepanek J et al: Case in point. Silo fillers lung. Hosp Pract (Minneap). 33(1):70, 1998
Gurney JW et al: Agricultural disorders of the lung. Radiographics. 11(4):625-34, 1991
Related Anatomy
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Related Differential Diagnoses
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References
Tables
Tables
KEY FACTS
Terminology
Imaging
Top Differential Diagnoses
Clinical Issues
Diagnostic Checklist
TERMINOLOGY
Abbreviations
Nitrogen dioxide (NO₂)
Definitions
Occupational lung disease resulting from exposure to NO₂
Inhalation of toxic gases from freshly stored silage
Similar gases: Welding, glassblowing, Zamboni ice resurfacing, manufacturing (lacquers, dyes, rocket propellants, fertilizers), metal cleaning, rayon and food bleaching, nitrocellulose incineration
IMAGING
General Features
Radiographic Findings
CT Findings
Nuclear Medicine Findings
Imaging Recommendations
DIFFERENTIAL DIAGNOSIS
PATHOLOGY
General Features
Microscopic Features
CLINICAL ISSUES
Presentation
Demographics
Natural History & Prognosis
Treatment
DIAGNOSTIC CHECKLIST
Consider
Selected References
Amaducci A et al: Nitrogen Dioxide Toxicity 2021
Amaza IP et al: Silo-filler's disease: one health system's experience and an update of the literature. J Agromedicine. 25(1):8-13, 2020
Leavey JF et al: Silo-filler's disease, the acute respiratory distress syndrome, and oxides of nitrogen. Ann Intern Med. 141(5):410-1, 2004
Jackson L: Grain silo cleanup operation leads to two occupational deaths. Appl Occup Environ Hyg. 17(7):464-6, 2002
Stepanek J et al: Case in point. Silo fillers lung. Hosp Pract (Minneap). 33(1):70, 1998
Gurney JW et al: Agricultural disorders of the lung. Radiographics. 11(4):625-34, 1991
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