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KEY FACTS
Terminology
Imaging
Top Differential Diagnoses
Clinical Issues
Diagnostic Checklist
TERMINOLOGY
Synonyms
- 2-vessel cord
- Absent umbilical artery (UA)
Definitions
- Single umbilical artery (SUA) cord has 1 umbilical artery (UA) and 1 umbilical vein (UV) instead of 2 UAs and 1 UV
- Hypoplastic UA (HUA) is variant of SUA
- HUA is < 1/2 size of normal UA
IMAGING
General Features
Ultrasonographic Findings
Imaging Recommendations
DIFFERENTIAL DIAGNOSIS
PATHOLOGY
General Features
Staging, Grading, & Classification
Gross Pathologic & Surgical Features
CLINICAL ISSUES
Presentation
Demographics
Natural History & Prognosis
DIAGNOSTIC CHECKLIST
Consider
Image Interpretation Pearls
Selected References
- Tai C et al: Prevalence of congenital heart disease in an isolated single umbilical artery is low at a tertiary referral center. J Ultrasound Med. ePub, 2020
- Ismail KI et al: Role of 2-dimensional ultrasound imaging in placental and umbilical cord morphometry: literature and pictorial review. J Ultrasound Med. 38(12):3131-40, 2019
- Hasegawa J: Ultrasound screening of umbilical cord abnormalities and delivery management. Placenta. 62:66-78, 2018
- Luo X et al: The risk factors and neonatal outcomes of isolated single umbilical artery in singleton pregnancy: a meta-analysis. Sci Rep. 7(1):7396, 2017
- Ebrashy A et al: Controversial ultrasound findings in mid trimester pregnancy. Evidence based approach. J Perinat Med. 44(2):131-7, 2016
- Battarbee AN et al: Association of isolated single umbilical artery with small for gestational age and preterm birth. Obstet Gynecol. 126(4):760-4, 2015
- Tulek F et al: The effects of isolated single umbilical artery on first and second trimester aneuploidy screening test parameters. J Matern Fetal Neonatal Med. 28(6):690-4, 2015
- Voskamp BJ et al: Relationship of isolated single umbilical artery to fetal growth, aneuploidy and perinatal mortality: systematic review and meta-analysis. Ultrasound Obstet Gynecol. 42(6):622-8, 2013
- Hua M et al: Single umbilical artery and its associated findings. Obstet Gynecol. 115(5):930-4, 2010
- Rembouskos G et al: Single umbilical artery at 11-14 weeks' gestation: relation to chromosomal defects. Ultrasound Obstet Gynecol. 22(6):567-70, 2003
- Gamzu R et al: Type II single umbilical artery (persistent vitelline artery) in an otherwise normal fetus. Prenat Diagn. 22(11):1040-3, 2002
Related Anatomy
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Related Differential Diagnoses
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References
Tables
Tables
KEY FACTS
Terminology
Imaging
Top Differential Diagnoses
Clinical Issues
Diagnostic Checklist
TERMINOLOGY
Synonyms
- 2-vessel cord
- Absent umbilical artery (UA)
Definitions
- Single umbilical artery (SUA) cord has 1 umbilical artery (UA) and 1 umbilical vein (UV) instead of 2 UAs and 1 UV
- Hypoplastic UA (HUA) is variant of SUA
- HUA is < 1/2 size of normal UA
IMAGING
General Features
Ultrasonographic Findings
Imaging Recommendations
DIFFERENTIAL DIAGNOSIS
PATHOLOGY
General Features
Staging, Grading, & Classification
Gross Pathologic & Surgical Features
CLINICAL ISSUES
Presentation
Demographics
Natural History & Prognosis
DIAGNOSTIC CHECKLIST
Consider
Image Interpretation Pearls
Selected References
- Tai C et al: Prevalence of congenital heart disease in an isolated single umbilical artery is low at a tertiary referral center. J Ultrasound Med. ePub, 2020
- Ismail KI et al: Role of 2-dimensional ultrasound imaging in placental and umbilical cord morphometry: literature and pictorial review. J Ultrasound Med. 38(12):3131-40, 2019
- Hasegawa J: Ultrasound screening of umbilical cord abnormalities and delivery management. Placenta. 62:66-78, 2018
- Luo X et al: The risk factors and neonatal outcomes of isolated single umbilical artery in singleton pregnancy: a meta-analysis. Sci Rep. 7(1):7396, 2017
- Ebrashy A et al: Controversial ultrasound findings in mid trimester pregnancy. Evidence based approach. J Perinat Med. 44(2):131-7, 2016
- Battarbee AN et al: Association of isolated single umbilical artery with small for gestational age and preterm birth. Obstet Gynecol. 126(4):760-4, 2015
- Tulek F et al: The effects of isolated single umbilical artery on first and second trimester aneuploidy screening test parameters. J Matern Fetal Neonatal Med. 28(6):690-4, 2015
- Voskamp BJ et al: Relationship of isolated single umbilical artery to fetal growth, aneuploidy and perinatal mortality: systematic review and meta-analysis. Ultrasound Obstet Gynecol. 42(6):622-8, 2013
- Hua M et al: Single umbilical artery and its associated findings. Obstet Gynecol. 115(5):930-4, 2010
- Rembouskos G et al: Single umbilical artery at 11-14 weeks' gestation: relation to chromosomal defects. Ultrasound Obstet Gynecol. 22(6):567-70, 2003
- Gamzu R et al: Type II single umbilical artery (persistent vitelline artery) in an otherwise normal fetus. Prenat Diagn. 22(11):1040-3, 2002
