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Sinonasal Fibroosseous and Cartilaginous Lesions
Axel Ruprecht, DDS, MScD, FRCD(C)
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DIFFERENTIAL DIAGNOSIS

    ESSENTIAL INFORMATION

    • Key Differential Diagnosis Issues

      • Helpful Clues for Common Diagnoses

        • Helpful Clues for Less Common Diagnoses

          • Helpful Clues for Rare Diagnoses

            Selected References

            1. Ali IK et al: Non-familial cherubism with bilateral maxilla and mandible involvement - clinicoradiographic Findings. Cureus. 8(7):e709, 2016
            2. Gupta D et al: Unusual presentation of chordoma in nose. Indian J Otolaryngol Head Neck Surg. 68(3):380-3, 2016
            3. Kadlub N et al: Defining a new aggressiveness classification and using NFATc1 localization as a prognostic factor in cherubism. Hum Pathol. ePub, 2016
            4. Kochar I et al: Early presentation of cherubism. Indian Pediatr. 53(8):751, 2016
            5. Nimonkar P et al: Myxoid chondrosarcoma of maxilla in a pediatric patient: A rare case report. Case Rep Oncol Med. 2016:5419737, 2016
            6. Zhang R et al: Incidental detection of ossifying fibroma of the frontal dinus on 99mTc-MDP bone scan. Clin Nucl Med. 41(1):e51-2, 2016
            7. Bhattacharya S et al: Fibrous dysplasia and cherubism. Indian J Plast Surg. 48(3):236-48, 2015
            8. Campbell RG et al: Contemporary management of clival chordomas. Curr Opin Otolaryngol Head Neck Surg. 23(2):153-61, 2015
            9. Ciniglio Appiani M et al: Ossifying fibromas of the paranasal sinuses: diagnosis and management. Acta Otorhinolaryngol Ital. 35(5):355-61, 2015
            10. Di Maio S et al: Novel targeted therapies in chordoma: An update. Ther Clin Risk Manag. 11:873-83, 2015
            11. Gantala R et al: Psammomatoid juvenile ossifying fibroma involving upper jaw: A rare case report. J Clin Diagn Res. 9(7):ZD17-9, 2015
            12. Jiao Y et al: Cherubism misdiagnosed as giant cell tumor: a case report and review of literature. Int J Clin Exp Med. 8(3):4656-63, 2015
            13. Kadlub N et al: The calcineurin inhibitor tacrolimus as a new therapy in severe cherubism. J Bone Miner Res. 30(5):878-85, 2015
            14. Lee JH et al: Underestimation of rhinogenic causes in patients presenting to the emergency department with acute headache. Acta Neurol Taiwan. 24(2):37-42, 2015
            15. Mahomed F et al: Ossifying fibroma in a patient With oculocerebrocutaneous (Delleman) syndrome. J Oral Maxillofac Surg. 73(7):1314-9, 2015
            16. Misra SR et al: Giant central ossifying fibroma of the maxilla presenting with a pus discharging intra-oral sinus. J Clin Diagn Res. 9(1):ZD08-11, 2015
            17. Pinto WB et al: Ossifying fibroma of the maxilla and tuberous sclerosis complex. Neurology. 84(15):1611-2, 2015
            18. Seifert M et al: Bone markers in craniofacial bone deformations and dysplasias. Postepy Hig Med Dosw (Online). 69:1176-81, 2015
            19. Shaik M et al: Juvenile ossifying fibroma of the maxilla: a case report. J Maxillofac Oral Surg. 14(Suppl 1):69-72, 2015
            20. Tu X et al: [Giant ossifying fibroma of nasal cavity and nasal sinuses: one case report.] Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 29(16):1492-3, 2015
            21. Vura NG et al: Surgical management of ossifying fibroma in maxilla: Report of two cases. J Int Oral Health. 7(6):115-8, 2015
            22. Woo SB: Central cemento-ossifying fibroma: Primary odontogenic or osseous neoplasm? J Oral Maxillofac Surg. 73(12 Suppl):S87-93, 2015
            23. Ye P et al: Intranasal endoscopic prelacrimal recess approach to sinonasal juvenile ossifying fibroma. Chin Med J (Engl). 128(3):425-6, 2015
            24. Coca-Pelaz A et al: Chondrosarcomas of the head and neck. Eur Arch Otorhinolaryngol. 271(10):2601-9, 2014
            25. Kuntzler S et al: Arrested pneumatization: witness of paranasal sinuses development? Eur Ann Otorhinolaryngol Head Neck Dis. 131(3):167-70, 2014
            26. Misra SR et al: Cherubism with multiple dental abnormalities: a rare presentation. BMJ Case Rep. 2014, 2014
            27. Mohanty S et al: Retrospective analysis of ossifying fibroma of jaw bones over a period of 10 years with literature review. J Maxillofac Oral Surg. 13(4):560-7, 2014
            28. Muthuraman V et al: Familial case of cherubism from South India: Differential diagnosis and report of 2 cases. Case Rep Dent. 2014:869783, 2014
            29. Nayak DR et al: Incidental 'ethmoid sinolith'--an unusual cause of frontal recess obstruction. BMJ Case Rep. 2014, 2014
            30. Peterson BR et al: Juvenile active ossifying fibroma. Head Neck Pathol. ePub, 2014
            31. DeKlotz TR et al: Sinonasal disease in polyostotic fibrous dysplasia and McCune-Albright Syndrome. Laryngoscope. 123(4):823-8, 2013
            32. Ozturan O et al: Chondroma of the nasal tip. J Craniofac Surg. 24(2):e153-5, 2013
            33. Park HJ et al: Fibrous dysplasia of the inferior turbinate. Int J Clin Exp Pathol. 6(3):531-5, 2013
            34. Sun N et al: A case of ossifying fibroma of the frontal sinus. Exp Ther Med. 5(5):1359-1362, 2013
            35. Assaf AT et al: Craniofacial fibrous dysplasia (CFD) of the maxilla in an 11-year-old boy: a case report. J Craniomaxillofac Surg. 40(8):788-92, 2012
            36. Karligkiotis A et al: Monostotic fibrous dysplasia of the inferior turbinate. Otolaryngol Head Neck Surg. 146(6):1035-6, 2012
            37. Schreiber A et al: Fibrous dysplasia of the sinonasal tract and adjacent skull base. Curr Opin Otolaryngol Head Neck Surg. 20(1):45-52, 2012
            38. Bohn OL et al: Trabecular and psammomatoid juvenile ossifying fibroma of the skull base mimicking psammomatoid meningioma. Head Neck Pathol. 5(1):71-5, 2011
            39. Edmond M et al: A large atypical osteoma of the maxillary sinus: a report of a case and management challenges. Eur Arch Otorhinolaryngol. 268(2):315-8, 2011
            40. Sontakke SA et al: Computed tomographic features of fibrous dysplasia of maxillofacial region. Imaging Sci Dent. 41(1):23-8, 2011
            41. Triantafillidou K et al: Central giant cell granuloma of the jaws: a clinical study of 17 cases and a review of the literature. Ann Otol Rhinol Laryngol. 120(3):167-74, 2011
            42. Almasi M et al: Sinolith in the ethmoid sinus: report of two cases and review of the literature. Eur Arch Otorhinolaryngol. 267(10):1649-52, 2010
            43. Bilodeau E et al: A case of recurrent multifocal central giant cell granulomas. Head Neck Pathol. 3(2):174-8, 2009
            44. Boudewyns AN et al: Sinonasal fibro-osseous hamartoma: case presentation and differential diagnosis with other fibro-osseous lesions involving the paranasal sinuses. Eur Arch Otorhinolaryngol. 263(3):276-81, 2006
            45. Eller R et al: Common fibro-osseous lesions of the paranasal sinuses. Otolaryngol Clin North Am. 39(3):585-600, x, 2006
            46. Vanel D et al: Pseudotumoural fibrous dysplasia of the maxilla: radiological studies and computed tomography contribution. Skeletal Radiol. 5(2):99-103, 1980
            Related Anatomy
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            Related Differential Diagnoses
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            References
            Tables

            Tables

            DIFFERENTIAL DIAGNOSIS

              ESSENTIAL INFORMATION

              • Key Differential Diagnosis Issues

                • Helpful Clues for Common Diagnoses

                  • Helpful Clues for Less Common Diagnoses

                    • Helpful Clues for Rare Diagnoses

                      Selected References

                      1. Ali IK et al: Non-familial cherubism with bilateral maxilla and mandible involvement - clinicoradiographic Findings. Cureus. 8(7):e709, 2016
                      2. Gupta D et al: Unusual presentation of chordoma in nose. Indian J Otolaryngol Head Neck Surg. 68(3):380-3, 2016
                      3. Kadlub N et al: Defining a new aggressiveness classification and using NFATc1 localization as a prognostic factor in cherubism. Hum Pathol. ePub, 2016
                      4. Kochar I et al: Early presentation of cherubism. Indian Pediatr. 53(8):751, 2016
                      5. Nimonkar P et al: Myxoid chondrosarcoma of maxilla in a pediatric patient: A rare case report. Case Rep Oncol Med. 2016:5419737, 2016
                      6. Zhang R et al: Incidental detection of ossifying fibroma of the frontal dinus on 99mTc-MDP bone scan. Clin Nucl Med. 41(1):e51-2, 2016
                      7. Bhattacharya S et al: Fibrous dysplasia and cherubism. Indian J Plast Surg. 48(3):236-48, 2015
                      8. Campbell RG et al: Contemporary management of clival chordomas. Curr Opin Otolaryngol Head Neck Surg. 23(2):153-61, 2015
                      9. Ciniglio Appiani M et al: Ossifying fibromas of the paranasal sinuses: diagnosis and management. Acta Otorhinolaryngol Ital. 35(5):355-61, 2015
                      10. Di Maio S et al: Novel targeted therapies in chordoma: An update. Ther Clin Risk Manag. 11:873-83, 2015
                      11. Gantala R et al: Psammomatoid juvenile ossifying fibroma involving upper jaw: A rare case report. J Clin Diagn Res. 9(7):ZD17-9, 2015
                      12. Jiao Y et al: Cherubism misdiagnosed as giant cell tumor: a case report and review of literature. Int J Clin Exp Med. 8(3):4656-63, 2015
                      13. Kadlub N et al: The calcineurin inhibitor tacrolimus as a new therapy in severe cherubism. J Bone Miner Res. 30(5):878-85, 2015
                      14. Lee JH et al: Underestimation of rhinogenic causes in patients presenting to the emergency department with acute headache. Acta Neurol Taiwan. 24(2):37-42, 2015
                      15. Mahomed F et al: Ossifying fibroma in a patient With oculocerebrocutaneous (Delleman) syndrome. J Oral Maxillofac Surg. 73(7):1314-9, 2015
                      16. Misra SR et al: Giant central ossifying fibroma of the maxilla presenting with a pus discharging intra-oral sinus. J Clin Diagn Res. 9(1):ZD08-11, 2015
                      17. Pinto WB et al: Ossifying fibroma of the maxilla and tuberous sclerosis complex. Neurology. 84(15):1611-2, 2015
                      18. Seifert M et al: Bone markers in craniofacial bone deformations and dysplasias. Postepy Hig Med Dosw (Online). 69:1176-81, 2015
                      19. Shaik M et al: Juvenile ossifying fibroma of the maxilla: a case report. J Maxillofac Oral Surg. 14(Suppl 1):69-72, 2015
                      20. Tu X et al: [Giant ossifying fibroma of nasal cavity and nasal sinuses: one case report.] Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 29(16):1492-3, 2015
                      21. Vura NG et al: Surgical management of ossifying fibroma in maxilla: Report of two cases. J Int Oral Health. 7(6):115-8, 2015
                      22. Woo SB: Central cemento-ossifying fibroma: Primary odontogenic or osseous neoplasm? J Oral Maxillofac Surg. 73(12 Suppl):S87-93, 2015
                      23. Ye P et al: Intranasal endoscopic prelacrimal recess approach to sinonasal juvenile ossifying fibroma. Chin Med J (Engl). 128(3):425-6, 2015
                      24. Coca-Pelaz A et al: Chondrosarcomas of the head and neck. Eur Arch Otorhinolaryngol. 271(10):2601-9, 2014
                      25. Kuntzler S et al: Arrested pneumatization: witness of paranasal sinuses development? Eur Ann Otorhinolaryngol Head Neck Dis. 131(3):167-70, 2014
                      26. Misra SR et al: Cherubism with multiple dental abnormalities: a rare presentation. BMJ Case Rep. 2014, 2014
                      27. Mohanty S et al: Retrospective analysis of ossifying fibroma of jaw bones over a period of 10 years with literature review. J Maxillofac Oral Surg. 13(4):560-7, 2014
                      28. Muthuraman V et al: Familial case of cherubism from South India: Differential diagnosis and report of 2 cases. Case Rep Dent. 2014:869783, 2014
                      29. Nayak DR et al: Incidental 'ethmoid sinolith'--an unusual cause of frontal recess obstruction. BMJ Case Rep. 2014, 2014
                      30. Peterson BR et al: Juvenile active ossifying fibroma. Head Neck Pathol. ePub, 2014
                      31. DeKlotz TR et al: Sinonasal disease in polyostotic fibrous dysplasia and McCune-Albright Syndrome. Laryngoscope. 123(4):823-8, 2013
                      32. Ozturan O et al: Chondroma of the nasal tip. J Craniofac Surg. 24(2):e153-5, 2013
                      33. Park HJ et al: Fibrous dysplasia of the inferior turbinate. Int J Clin Exp Pathol. 6(3):531-5, 2013
                      34. Sun N et al: A case of ossifying fibroma of the frontal sinus. Exp Ther Med. 5(5):1359-1362, 2013
                      35. Assaf AT et al: Craniofacial fibrous dysplasia (CFD) of the maxilla in an 11-year-old boy: a case report. J Craniomaxillofac Surg. 40(8):788-92, 2012
                      36. Karligkiotis A et al: Monostotic fibrous dysplasia of the inferior turbinate. Otolaryngol Head Neck Surg. 146(6):1035-6, 2012
                      37. Schreiber A et al: Fibrous dysplasia of the sinonasal tract and adjacent skull base. Curr Opin Otolaryngol Head Neck Surg. 20(1):45-52, 2012
                      38. Bohn OL et al: Trabecular and psammomatoid juvenile ossifying fibroma of the skull base mimicking psammomatoid meningioma. Head Neck Pathol. 5(1):71-5, 2011
                      39. Edmond M et al: A large atypical osteoma of the maxillary sinus: a report of a case and management challenges. Eur Arch Otorhinolaryngol. 268(2):315-8, 2011
                      40. Sontakke SA et al: Computed tomographic features of fibrous dysplasia of maxillofacial region. Imaging Sci Dent. 41(1):23-8, 2011
                      41. Triantafillidou K et al: Central giant cell granuloma of the jaws: a clinical study of 17 cases and a review of the literature. Ann Otol Rhinol Laryngol. 120(3):167-74, 2011
                      42. Almasi M et al: Sinolith in the ethmoid sinus: report of two cases and review of the literature. Eur Arch Otorhinolaryngol. 267(10):1649-52, 2010
                      43. Bilodeau E et al: A case of recurrent multifocal central giant cell granulomas. Head Neck Pathol. 3(2):174-8, 2009
                      44. Boudewyns AN et al: Sinonasal fibro-osseous hamartoma: case presentation and differential diagnosis with other fibro-osseous lesions involving the paranasal sinuses. Eur Arch Otorhinolaryngol. 263(3):276-81, 2006
                      45. Eller R et al: Common fibro-osseous lesions of the paranasal sinuses. Otolaryngol Clin North Am. 39(3):585-600, x, 2006
                      46. Vanel D et al: Pseudotumoural fibrous dysplasia of the maxilla: radiological studies and computed tomography contribution. Skeletal Radiol. 5(2):99-103, 1980