Benign epithelial tumor of nasal mucosa with histology showing epithelium proliferating into underlying stroma
IMAGING
General Features
CT Findings
MR Findings
Imaging Recommendations
Nuclear Medicine Findings
DIFFERENTIAL DIAGNOSIS
PATHOLOGY
General Features
Staging, Grading, & Classification
Gross Pathologic & Surgical Features
Microscopic Features
CLINICAL ISSUES
Presentation
Demographics
Natural History & Prognosis
Treatment
DIAGNOSTIC CHECKLIST
Consider
Image Interpretation Pearls
Selected References
Paehler Vor der Holte A et al: Impact of human papillomaviruses (HPV) on recurrence rate and malignant progression of sinonasal papillomas. Cancer Med. 10(2):634-41, 2021
Yan CH et al: Imaging predictors for malignant transformation of inverted papilloma. Laryngoscope. 129(4):777-82, 2019
Adriaensen GF et al: Challenges in the management of inverted papilloma: a review of 72 revision cases. Laryngoscope. 126(2):322-8, 2016
Zhao RW et al: Human papillomavirus infection and the malignant transformation of sinonasal inverted papilloma: a meta-analysis. J Clin Virol. 79:36-43, 2016
Hong SL et al: Smoking and malignancy in sinonasal inverted papilloma. Laryngoscope. 123(5):1087-91, 2013
Sasaki M et al: Apparent diffusion coefficient mapping for sinonasal diseases: differentiation of benign and malignant lesions. AJNR Am J Neuroradiol. 32(6):1100-6, 2011
Jeon TY et al: 18F-FDG PET/CT findings of sinonasal inverted papilloma with or without coexistent malignancy: comparison with MR imaging findings in eight patients. Neuroradiology. 51(4):265-71, 2009
Karkos PD et al: Computed tomography and/or magnetic resonance imaging for pre-operative planning for inverted nasal papilloma: review of evidence. J Laryngol Otol. 123(7):705-9, 2009
Kim WS et al: Treatment outcomes of sinonasal inverted papillomas according to surgical approaches. Acta Otolaryngol.130(4):493-7, 2009
Sham CL et al: A case-control study of the risk factors associated with sinonasal inverted papilloma. Am J Rhinol Allergy. 24(1):e37-40, 2009
Sham CL et al: Treatment results of sinonasal inverted papilloma: an 18-year study. Am J Rhinol Allergy. 23(2):203-11, 2009
Jeon TY et al: Sinonasal inverted papilloma: value of convoluted cerebriform pattern on MR imaging. AJNR Am J Neuroradiol. 29(8):1556-60, 2008
Sham CL et al: The roles and limitations of computed tomography in the preoperative assessment of sinonasal inverted papillomas. Am J Rhinol. 22(2):144-50, 2008
Cannady SB et al: New staging system for sinonasal inverted papilloma in the endoscopic era. Laryngoscope. 117(7):1283-7, 2007
Head CS et al: Radiographic assessment of inverted papilloma. Acta Otolaryngol. 127(5):515-20, 2007
Lee DK et al: Focal hyperostosis on CT of sinonasal inverted papilloma as a predictor of tumor origin. AJNR Am J Neuroradiol. 28(4):618-21, 2007
Mirza S et al: Sinonasal inverted papillomas: recurrence, and synchronous and metachronous malignancy. J Laryngol Otol. 121(9):857-64, 2007
Shojaku H et al: Positron emission tomography for predicting malignancy of sinonasal inverted papilloma. Clin Nucl Med. 32(4):275-8, 2007
Stephen JK et al: Epigenetic events underlie the pathogenesis of sinonasal papillomas. Mod Pathol. 20(10):1019-27, 2007
von Buchwald C et al: Risks of malignancy in inverted papilloma of the nose and paranasal sinuses. Curr Opin Otolaryngol Head Neck Surg. 15(2):95-8, 2007
Yousuf K et al: Site of attachment of inverted papilloma predicted by CT findings of osteitis. Am J Rhinol. 21(1):32-6, 2007
Chiu AG et al: Radiographic and histologic analysis of the bone underlying inverted papillomas. Laryngoscope. 116(9):1617-20, 2006
Melroy CT et al: Benign sinonasal neoplasms: a focus on inverting papilloma. Otolaryngol Clin North Am. 39(3):601-17, x, 2006
Maroldi R et al: Magnetic resonance imaging findings of inverted papilloma: differential diagnosis with malignant sinonasal tumors. Am J Rhinol. 18(5):305-10, 2004
Tomenzoli D et al: Different endoscopic surgical strategies in the management of inverted papilloma of the sinonasal tract: experience with 47 patients. Laryngoscope. 114(2):193-200, 2004
Klimek T et al: Inverted papilloma of the nasal cavity and paranasal sinuses: clinical data, surgical strategy and recurrence rates. Acta Otolaryngol. 120(2):267-72, 2000
Ojiri H et al: Potentially distinctive features of sinonasal inverted papilloma on MR imaging. AJR Am J Roentgenol. 175(2):465-8, 2000
Petit P et al: Radiological follow-up of inverted papilloma. Eur Radiol. 10(7):1184-9, 2000
Savy L et al: Optimum imaging for inverted papilloma. J Laryngol Otol. 114(11):891-3, 2000
Dammann F et al: Inverted papilloma of the nasal cavity and the paranasal sinuses: using CT for primary diagnosis and follow-up. AJR Am J Roentgenol. 172(2):543-8, 1999
Roobottom CA et al: Primary and recurrent inverting papilloma: appearances with magnetic resonance imaging. Clin Radiol. 50(7):472-5, 1995
Yousem DM et al: Inverted papilloma: evaluation with MR imaging. Radiology. 185(2):501-5, 1992
Phillips PP et al: The clinical behavior of inverting papilloma of the nose and paranasal sinuses: report of 112 cases and review of the literature. Laryngoscope. 100(5):463-9, 1990
Benign epithelial tumor of nasal mucosa with histology showing epithelium proliferating into underlying stroma
IMAGING
General Features
CT Findings
MR Findings
Imaging Recommendations
Nuclear Medicine Findings
DIFFERENTIAL DIAGNOSIS
PATHOLOGY
General Features
Staging, Grading, & Classification
Gross Pathologic & Surgical Features
Microscopic Features
CLINICAL ISSUES
Presentation
Demographics
Natural History & Prognosis
Treatment
DIAGNOSTIC CHECKLIST
Consider
Image Interpretation Pearls
Selected References
Paehler Vor der Holte A et al: Impact of human papillomaviruses (HPV) on recurrence rate and malignant progression of sinonasal papillomas. Cancer Med. 10(2):634-41, 2021
Yan CH et al: Imaging predictors for malignant transformation of inverted papilloma. Laryngoscope. 129(4):777-82, 2019
Adriaensen GF et al: Challenges in the management of inverted papilloma: a review of 72 revision cases. Laryngoscope. 126(2):322-8, 2016
Zhao RW et al: Human papillomavirus infection and the malignant transformation of sinonasal inverted papilloma: a meta-analysis. J Clin Virol. 79:36-43, 2016
Hong SL et al: Smoking and malignancy in sinonasal inverted papilloma. Laryngoscope. 123(5):1087-91, 2013
Sasaki M et al: Apparent diffusion coefficient mapping for sinonasal diseases: differentiation of benign and malignant lesions. AJNR Am J Neuroradiol. 32(6):1100-6, 2011
Jeon TY et al: 18F-FDG PET/CT findings of sinonasal inverted papilloma with or without coexistent malignancy: comparison with MR imaging findings in eight patients. Neuroradiology. 51(4):265-71, 2009
Karkos PD et al: Computed tomography and/or magnetic resonance imaging for pre-operative planning for inverted nasal papilloma: review of evidence. J Laryngol Otol. 123(7):705-9, 2009
Kim WS et al: Treatment outcomes of sinonasal inverted papillomas according to surgical approaches. Acta Otolaryngol.130(4):493-7, 2009
Sham CL et al: A case-control study of the risk factors associated with sinonasal inverted papilloma. Am J Rhinol Allergy. 24(1):e37-40, 2009
Sham CL et al: Treatment results of sinonasal inverted papilloma: an 18-year study. Am J Rhinol Allergy. 23(2):203-11, 2009
Jeon TY et al: Sinonasal inverted papilloma: value of convoluted cerebriform pattern on MR imaging. AJNR Am J Neuroradiol. 29(8):1556-60, 2008
Sham CL et al: The roles and limitations of computed tomography in the preoperative assessment of sinonasal inverted papillomas. Am J Rhinol. 22(2):144-50, 2008
Cannady SB et al: New staging system for sinonasal inverted papilloma in the endoscopic era. Laryngoscope. 117(7):1283-7, 2007
Head CS et al: Radiographic assessment of inverted papilloma. Acta Otolaryngol. 127(5):515-20, 2007
Lee DK et al: Focal hyperostosis on CT of sinonasal inverted papilloma as a predictor of tumor origin. AJNR Am J Neuroradiol. 28(4):618-21, 2007
Mirza S et al: Sinonasal inverted papillomas: recurrence, and synchronous and metachronous malignancy. J Laryngol Otol. 121(9):857-64, 2007
Shojaku H et al: Positron emission tomography for predicting malignancy of sinonasal inverted papilloma. Clin Nucl Med. 32(4):275-8, 2007
Stephen JK et al: Epigenetic events underlie the pathogenesis of sinonasal papillomas. Mod Pathol. 20(10):1019-27, 2007
von Buchwald C et al: Risks of malignancy in inverted papilloma of the nose and paranasal sinuses. Curr Opin Otolaryngol Head Neck Surg. 15(2):95-8, 2007
Yousuf K et al: Site of attachment of inverted papilloma predicted by CT findings of osteitis. Am J Rhinol. 21(1):32-6, 2007
Chiu AG et al: Radiographic and histologic analysis of the bone underlying inverted papillomas. Laryngoscope. 116(9):1617-20, 2006
Melroy CT et al: Benign sinonasal neoplasms: a focus on inverting papilloma. Otolaryngol Clin North Am. 39(3):601-17, x, 2006
Maroldi R et al: Magnetic resonance imaging findings of inverted papilloma: differential diagnosis with malignant sinonasal tumors. Am J Rhinol. 18(5):305-10, 2004
Tomenzoli D et al: Different endoscopic surgical strategies in the management of inverted papilloma of the sinonasal tract: experience with 47 patients. Laryngoscope. 114(2):193-200, 2004
Klimek T et al: Inverted papilloma of the nasal cavity and paranasal sinuses: clinical data, surgical strategy and recurrence rates. Acta Otolaryngol. 120(2):267-72, 2000
Ojiri H et al: Potentially distinctive features of sinonasal inverted papilloma on MR imaging. AJR Am J Roentgenol. 175(2):465-8, 2000
Petit P et al: Radiological follow-up of inverted papilloma. Eur Radiol. 10(7):1184-9, 2000
Savy L et al: Optimum imaging for inverted papilloma. J Laryngol Otol. 114(11):891-3, 2000
Dammann F et al: Inverted papilloma of the nasal cavity and the paranasal sinuses: using CT for primary diagnosis and follow-up. AJR Am J Roentgenol. 172(2):543-8, 1999
Roobottom CA et al: Primary and recurrent inverting papilloma: appearances with magnetic resonance imaging. Clin Radiol. 50(7):472-5, 1995
Yousem DM et al: Inverted papilloma: evaluation with MR imaging. Radiology. 185(2):501-5, 1992
Phillips PP et al: The clinical behavior of inverting papilloma of the nose and paranasal sinuses: report of 112 cases and review of the literature. Laryngoscope. 100(5):463-9, 1990
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