Malignant transformation of melanocytes migrating from neural crest in sinonasal cavity
IMAGING
General Features
CT Findings
MR Findings
Imaging Recommendations
DIFFERENTIAL DIAGNOSIS
PATHOLOGY
General Features
Staging, Grading, & Classification
Gross Pathologic & Surgical Features
Microscopic Features
CLINICAL ISSUES
Presentation
Demographics
Natural History & Prognosis
Treatment
DIAGNOSTIC CHECKLIST
Consider
Image Interpretation Pearls
Selected References
Zlochower AB et al: Doing great with DOTATATE: update on GA-68 DOTATATE positron emission tomography/computed tomography and magnetic resonance imaging for evaluation of sinonasal tumors. Top Magn Reson Imaging. 30(3):151-8, 2021
Kim YK et al: Melanoma of the sinonasal tract: value of a septate pattern on precontrast T1-weighted MR imaging. AJNR Am J Neuroradiol. 39(4):762-7, 2018
Alves IS et al: Sinonasal melanoma: a case report and literature review. Case Rep Oncol Med. 2017:8201301, 2017
Gras-Cabrerizo JR et al: Management of sinonasal mucosal melanomas and comparison of classification staging systems. Am J Rhinol Allergy. 29(1):e37-40, 2015
Jangard M et al: TERT promoter mutations in sinonasal malignant melanoma: a study of 49 cases. Melanoma Res. 25(3):185-8, 2015
Gilain L et al: Mucosal melanoma of the nasal cavity and paranasal sinuses. Eur Ann Otorhinolaryngol Head Neck Dis. 131(6):365-9, 2014
Michel J et al: Sinonasal mucosal melanomas: the prognostic value of tumor classifications. Head Neck. 36(3):311-6, 2014
Moreno MA et al: Mucosal melanoma of the nose and paranasal sinuses, a contemporary experience from the M. D. Anderson Cancer Center. Cancer. 116(9):2215-23, 2010
Wu AJ et al: Radiotherapy after surgical resection for head and neck mucosal melanoma. Am J Clin Oncol. 33(3):281-5, 2010
Dauer EH et al: Sinonasal melanoma: a clinicopathologic review of 61 cases. Otolaryngol Head Neck Surg. 138(3):347-52, 2008
Kim DK et al: Ki67 antigen as a predictive factor for prognosis of sinonasal mucosal melanoma. Clin Exp Otorhinolaryngol. 1(4):206-10, 2008
McLean N et al: Primary mucosal melanoma of the head and neck. Comparison of clinical presentation and histopathologic features of oral and sinonasal melanoma. Oral Oncol. 44(11):1039-46, 2008
Raghavan P et al: Magnetic resonance imaging of sinonasal malignancies. Top Magn Reson Imaging. 18(4):259-67, 2007
Day TA et al: Management of paranasal sinus malignancy. Curr Treat Options Oncol. 6(1):3-18, 2005
Chang PC et al: Perineural spread of malignant melanoma of the head and neck: clinical and imaging features. AJNR Am J Neuroradiol. 25(1):5-11, 2004
Loevner LA et al: Imaging of neoplasms of the paranasal sinuses. Magn Reson Imaging Clin N Am. 10(3):467-93, 2002
Kim SS et al: Malignant melanoma of the sinonasal cavity: explanation of magnetic resonance signal intensities with histopathologic characteristics. Am J Otolaryngol. 21(6):366-78, 2000
Yousem DM et al: Primary malignant melanoma of the sinonasal cavity: MR imaging evaluation. Radiographics. 16(5):1101-10, 1996
Related Anatomy
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Related Differential Diagnoses
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References
Tables
Tables
KEY FACTS
Terminology
Imaging
Top Differential Diagnoses
Clinical Issues
Diagnostic Checklist
TERMINOLOGY
Abbreviations
Sinonasal melanoma (SNM)
Definitions
Malignant transformation of melanocytes migrating from neural crest in sinonasal cavity
IMAGING
General Features
CT Findings
MR Findings
Imaging Recommendations
DIFFERENTIAL DIAGNOSIS
PATHOLOGY
General Features
Staging, Grading, & Classification
Gross Pathologic & Surgical Features
Microscopic Features
CLINICAL ISSUES
Presentation
Demographics
Natural History & Prognosis
Treatment
DIAGNOSTIC CHECKLIST
Consider
Image Interpretation Pearls
Selected References
Zlochower AB et al: Doing great with DOTATATE: update on GA-68 DOTATATE positron emission tomography/computed tomography and magnetic resonance imaging for evaluation of sinonasal tumors. Top Magn Reson Imaging. 30(3):151-8, 2021
Kim YK et al: Melanoma of the sinonasal tract: value of a septate pattern on precontrast T1-weighted MR imaging. AJNR Am J Neuroradiol. 39(4):762-7, 2018
Alves IS et al: Sinonasal melanoma: a case report and literature review. Case Rep Oncol Med. 2017:8201301, 2017
Gras-Cabrerizo JR et al: Management of sinonasal mucosal melanomas and comparison of classification staging systems. Am J Rhinol Allergy. 29(1):e37-40, 2015
Jangard M et al: TERT promoter mutations in sinonasal malignant melanoma: a study of 49 cases. Melanoma Res. 25(3):185-8, 2015
Gilain L et al: Mucosal melanoma of the nasal cavity and paranasal sinuses. Eur Ann Otorhinolaryngol Head Neck Dis. 131(6):365-9, 2014
Michel J et al: Sinonasal mucosal melanomas: the prognostic value of tumor classifications. Head Neck. 36(3):311-6, 2014
Moreno MA et al: Mucosal melanoma of the nose and paranasal sinuses, a contemporary experience from the M. D. Anderson Cancer Center. Cancer. 116(9):2215-23, 2010
Wu AJ et al: Radiotherapy after surgical resection for head and neck mucosal melanoma. Am J Clin Oncol. 33(3):281-5, 2010
Dauer EH et al: Sinonasal melanoma: a clinicopathologic review of 61 cases. Otolaryngol Head Neck Surg. 138(3):347-52, 2008
Kim DK et al: Ki67 antigen as a predictive factor for prognosis of sinonasal mucosal melanoma. Clin Exp Otorhinolaryngol. 1(4):206-10, 2008
McLean N et al: Primary mucosal melanoma of the head and neck. Comparison of clinical presentation and histopathologic features of oral and sinonasal melanoma. Oral Oncol. 44(11):1039-46, 2008
Raghavan P et al: Magnetic resonance imaging of sinonasal malignancies. Top Magn Reson Imaging. 18(4):259-67, 2007
Day TA et al: Management of paranasal sinus malignancy. Curr Treat Options Oncol. 6(1):3-18, 2005
Chang PC et al: Perineural spread of malignant melanoma of the head and neck: clinical and imaging features. AJNR Am J Neuroradiol. 25(1):5-11, 2004
Loevner LA et al: Imaging of neoplasms of the paranasal sinuses. Magn Reson Imaging Clin N Am. 10(3):467-93, 2002
Kim SS et al: Malignant melanoma of the sinonasal cavity: explanation of magnetic resonance signal intensities with histopathologic characteristics. Am J Otolaryngol. 21(6):366-78, 2000
Yousem DM et al: Primary malignant melanoma of the sinonasal cavity: MR imaging evaluation. Radiographics. 16(5):1101-10, 1996
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