Bookmarks
KEY FACTS
Imaging
Top Differential Diagnoses
Pathology
Clinical Issues
TERMINOLOGY
Definitions
- Expanded, chronically obstructed sinus, lined by normal respiratory epithelium and completely filled with mucus
- From Latin "muco" (mucus) + Greek "kele" (tumor) = "mucous tumor"
- Obstructed sinus and complete opacification without marginal bony expansion not considered mucocele
- Expanded, chronically obstructed sinus, lined by normal respiratory epithelium and completely filled with mucus
IMAGING
General Features
Radiographic Findings
CT Findings
MR Findings
Imaging Recommendations
DIFFERENTIAL DIAGNOSIS
PATHOLOGY
General Features
Staging, Grading, & Classification
Gross Pathologic & Surgical Features
Microscopic Features
CLINICAL ISSUES
Presentation
Demographics
Natural History & Prognosis
Treatment
DIAGNOSTIC CHECKLIST
Consider
Image Interpretation Pearls
Selected References
- Plantier DB et al: Mucocele: Clinical characteristics and outcomes in 46 operated patients. Int Arch Otorhinolaryngol. 23(1):88-91, 2019
- Al-Qudah M: Image-guided sinus surgery in sinonasal pathologies with skull base/orbital erosion. J Craniofac Surg. 26(5):1606-8, 2015
- Lee JC et al: Computed tomography image guidance for more accurate repair of anterior table frontal sinus fractures. J Craniofac Surg. 26(1):e64-7, 2015
- Samil KS et al: Nasal cavity and paranasal sinus diseases affecting orbit. J Craniofac Surg. 26(4):e348-51, 2015
- Aghakhanyan G et al: Delayed post-traumatic fronto-ethmoidal sinus mucocele evaluated with short and long TE MR spectroscopy. Neuroradiol J. 26(6):693-8, 2013
- Lee JT et al: Intracranial mucocele formation in the context of longstanding chronic rhinosinusitis: a clinicopathologic series and literature review. Allergy Rhinol (Providence). 4(3):e166-75, 2013
- Scangas GA et al: The natural history and clinical characteristics of paranasal sinus mucoceles: a clinical review. Int Forum Allergy Rhinol. 3(9):712-7, 2013
- Devars du Mayne M et al: Sinus mucocele: natural history and long-term recurrence rate. Eur Ann Otorhinolaryngol Head Neck Dis. 129(3):125-30, 2012
- Soon SR et al: Sphenoid sinus mucocele: 10 cases and literature review. J Laryngol Otol. 124(1):44-7, 2010
- Khalil SH et al: Clinico-radiological considerations in the treatment of frontal sinus mucoceles. Rev Laryngol Otol Rhinol (Bord). 130(4-5):267-71, 2009
- Lee TJ et al: Extensive paranasal sinus mucoceles: a 15-year review of 82 cases. Am J Otolaryngol. 30(4):234-8, 2009
- Sadiq SA et al: Ophthalmic manifestations of paranasal sinus mucocoeles. Int Ophthalmol. 29(2):75-9, 2009
- Sautter NB et al: Paranasal sinus mucoceles with skull-base and/or orbital erosion: is the endoscopic approach sufficient? Otolaryngol Head Neck Surg. 139(4):570-4, 2008
- Som PM et al: Interfrontal sinus septal cell: a cause of obstructing inflammation and mucoceles. AJNR Am J Neuroradiol. 29(7):1369-71, 2008
- Fu CH et al: The difference in anatomical and invasive characteristics between primary and secondary paranasal sinus mucoceles. Otolaryngol Head Neck Surg. 136(4):621-5, 2007
- Herndon M et al: Presentation and management of extensive fronto-orbital-ethmoid mucoceles. Am J Otolaryngol. 28(3):145-7, 2007
- Andre E et al: MR spectroscopy in sinus mucocele: N-acetyl mimics of brain N-acetylaspartate. AJNR Am J Neuroradiol. 27(10):2210-3, 2006
- Eggesbø HB: Radiological imaging of inflammatory lesions in the nasal cavity and paranasal sinuses. Eur Radiol. 16(4):872-88, 2006
- Nicollas R et al: Pediatric paranasal sinus mucoceles: etiologic factors, management and outcome. Int J Pediatr Otorhinolaryngol. 70(5):905-8, 2006
- Khong JJ et al: Endoscopic sinus surgery for paranasal sinus mucocoele with orbital involvement. Eye. 18(9):877-81, 2004
- Kosling S et al: Mucoceles of the sphenoid sinus. Eur J Radiol. 51(1):1-5, 2004
- Landsberg R et al: Magnetic resonance imaging--aided navigation in endoscopic sinus surgery of a bone-destructive sphenoclinoid mucocele. Ann Otol Rhinol Laryngol. 112(8):740-4, 2003
- Har-El G: Endoscopic management of 108 sinus mucoceles. Laryngoscope. 111(12): 2131-4, 2001
- Lloyd G et al: Optimum imaging for mucoceles. J Laryngol Otol. 114(3): 233-6, 2000
- Nakasato T et al: Virtual CT endoscopy in determining safe surgical entrance points for paranasal mucoceles. J Comput Assist Tomogr. 24(3): 486-92, 2000
- Rombaux P et al: Endoscopic endonasal surgery for paranasal sinus mucoceles. Acta Otorhinolaryngol Belg. 54(2): 115-22, 2000
- Busaba NY et al: Maxillary sinus mucoceles: clinical presentation and long-term results of endoscopic surgical treatment. Laryngoscope. 109(9): 1446-9, 1999
- Weissman JL et al: Double mucocele of the paranasal sinuses. AJNR Am J Neuroradiol. 15(7): 1263-4, 1994
- Van Tassel P et al: Mucoceles of the paranasal sinuses: MR imaging with CT correlation. AJR Am J Roentgenol. 153(2):407-12, 1989
- Field HJ et al: Characterization of latent infections in mice inoculated with herpes simplex virus which is clinically resistant to acyclovir. Antiviral Res. 4(1-2):43-52, 1984
- Hesselink JR et al: Evaluation of mucoceles of the paranasal sinuses with computed tomography. Radiology. 133(2):397-400, 1979
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References
Tables
Tables
KEY FACTS
Imaging
Top Differential Diagnoses
Pathology
Clinical Issues
TERMINOLOGY
Definitions
- Expanded, chronically obstructed sinus, lined by normal respiratory epithelium and completely filled with mucus
- From Latin "muco" (mucus) + Greek "kele" (tumor) = "mucous tumor"
- Obstructed sinus and complete opacification without marginal bony expansion not considered mucocele
- Expanded, chronically obstructed sinus, lined by normal respiratory epithelium and completely filled with mucus
IMAGING
General Features
Radiographic Findings
CT Findings
MR Findings
Imaging Recommendations
DIFFERENTIAL DIAGNOSIS
PATHOLOGY
General Features
Staging, Grading, & Classification
Gross Pathologic & Surgical Features
Microscopic Features
CLINICAL ISSUES
Presentation
Demographics
Natural History & Prognosis
Treatment
DIAGNOSTIC CHECKLIST
Consider
Image Interpretation Pearls
Selected References
- Plantier DB et al: Mucocele: Clinical characteristics and outcomes in 46 operated patients. Int Arch Otorhinolaryngol. 23(1):88-91, 2019
- Al-Qudah M: Image-guided sinus surgery in sinonasal pathologies with skull base/orbital erosion. J Craniofac Surg. 26(5):1606-8, 2015
- Lee JC et al: Computed tomography image guidance for more accurate repair of anterior table frontal sinus fractures. J Craniofac Surg. 26(1):e64-7, 2015
- Samil KS et al: Nasal cavity and paranasal sinus diseases affecting orbit. J Craniofac Surg. 26(4):e348-51, 2015
- Aghakhanyan G et al: Delayed post-traumatic fronto-ethmoidal sinus mucocele evaluated with short and long TE MR spectroscopy. Neuroradiol J. 26(6):693-8, 2013
- Lee JT et al: Intracranial mucocele formation in the context of longstanding chronic rhinosinusitis: a clinicopathologic series and literature review. Allergy Rhinol (Providence). 4(3):e166-75, 2013
- Scangas GA et al: The natural history and clinical characteristics of paranasal sinus mucoceles: a clinical review. Int Forum Allergy Rhinol. 3(9):712-7, 2013
- Devars du Mayne M et al: Sinus mucocele: natural history and long-term recurrence rate. Eur Ann Otorhinolaryngol Head Neck Dis. 129(3):125-30, 2012
- Soon SR et al: Sphenoid sinus mucocele: 10 cases and literature review. J Laryngol Otol. 124(1):44-7, 2010
- Khalil SH et al: Clinico-radiological considerations in the treatment of frontal sinus mucoceles. Rev Laryngol Otol Rhinol (Bord). 130(4-5):267-71, 2009
- Lee TJ et al: Extensive paranasal sinus mucoceles: a 15-year review of 82 cases. Am J Otolaryngol. 30(4):234-8, 2009
- Sadiq SA et al: Ophthalmic manifestations of paranasal sinus mucocoeles. Int Ophthalmol. 29(2):75-9, 2009
- Sautter NB et al: Paranasal sinus mucoceles with skull-base and/or orbital erosion: is the endoscopic approach sufficient? Otolaryngol Head Neck Surg. 139(4):570-4, 2008
- Som PM et al: Interfrontal sinus septal cell: a cause of obstructing inflammation and mucoceles. AJNR Am J Neuroradiol. 29(7):1369-71, 2008
- Fu CH et al: The difference in anatomical and invasive characteristics between primary and secondary paranasal sinus mucoceles. Otolaryngol Head Neck Surg. 136(4):621-5, 2007
- Herndon M et al: Presentation and management of extensive fronto-orbital-ethmoid mucoceles. Am J Otolaryngol. 28(3):145-7, 2007
- Andre E et al: MR spectroscopy in sinus mucocele: N-acetyl mimics of brain N-acetylaspartate. AJNR Am J Neuroradiol. 27(10):2210-3, 2006
- Eggesbø HB: Radiological imaging of inflammatory lesions in the nasal cavity and paranasal sinuses. Eur Radiol. 16(4):872-88, 2006
- Nicollas R et al: Pediatric paranasal sinus mucoceles: etiologic factors, management and outcome. Int J Pediatr Otorhinolaryngol. 70(5):905-8, 2006
- Khong JJ et al: Endoscopic sinus surgery for paranasal sinus mucocoele with orbital involvement. Eye. 18(9):877-81, 2004
- Kosling S et al: Mucoceles of the sphenoid sinus. Eur J Radiol. 51(1):1-5, 2004
- Landsberg R et al: Magnetic resonance imaging--aided navigation in endoscopic sinus surgery of a bone-destructive sphenoclinoid mucocele. Ann Otol Rhinol Laryngol. 112(8):740-4, 2003
- Har-El G: Endoscopic management of 108 sinus mucoceles. Laryngoscope. 111(12): 2131-4, 2001
- Lloyd G et al: Optimum imaging for mucoceles. J Laryngol Otol. 114(3): 233-6, 2000
- Nakasato T et al: Virtual CT endoscopy in determining safe surgical entrance points for paranasal mucoceles. J Comput Assist Tomogr. 24(3): 486-92, 2000
- Rombaux P et al: Endoscopic endonasal surgery for paranasal sinus mucoceles. Acta Otorhinolaryngol Belg. 54(2): 115-22, 2000
- Busaba NY et al: Maxillary sinus mucoceles: clinical presentation and long-term results of endoscopic surgical treatment. Laryngoscope. 109(9): 1446-9, 1999
- Weissman JL et al: Double mucocele of the paranasal sinuses. AJNR Am J Neuroradiol. 15(7): 1263-4, 1994
- Van Tassel P et al: Mucoceles of the paranasal sinuses: MR imaging with CT correlation. AJR Am J Roentgenol. 153(2):407-12, 1989
- Field HJ et al: Characterization of latent infections in mice inoculated with herpes simplex virus which is clinically resistant to acyclovir. Antiviral Res. 4(1-2):43-52, 1984
- Hesselink JR et al: Evaluation of mucoceles of the paranasal sinuses with computed tomography. Radiology. 133(2):397-400, 1979
