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Sinonasal Ossifying Fibroma
Blair A. Winegar, MD
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KEY FACTS

  • Terminology

    • Imaging

      • Top Differential Diagnoses

        • Pathology

          • Clinical Issues

            TERMINOLOGY

            • Abbreviations

              • Ossifying fibroma (OsFib)
            • Synonyms

              • Cementoossifying fibroma, psammomatoid ossifying fibroma, juvenile-aggressive ossifying fibroma
            • Definitions

              • Benign fibroosseous lesion composed of encapsulated mixture of fibrous tissue & mature bone

            IMAGING

            • General Features

              • CT Findings

                • MR Findings

                  • Imaging Recommendations

                    DIFFERENTIAL DIAGNOSIS

                      PATHOLOGY

                      • General Features

                        • Staging, Grading, & Classification

                          • Gross Pathologic & Surgical Features

                            • Microscopic Features

                              CLINICAL ISSUES

                              • Presentation

                                • Demographics

                                  • Natural History & Prognosis

                                    • Treatment

                                      DIAGNOSTIC CHECKLIST

                                      • Consider

                                        • Image Interpretation Pearls

                                          • Reporting Tips

                                            Selected References

                                            1. Ciniglio Appiani M et al: Ossifying fibromas of the paranasal sinuses: diagnosis and management. Acta Otorhinolaryngol Ital. 35(5):355-61, 2015
                                            2. MacDonald DS: Maxillofacial fibro-osseous lesions. Clin Radiol. 70(1):25-36, 2015
                                            3. McCarthy EF: Fibro-osseous lesions of the maxillofacial bones. Head Neck Pathol. 7(1):5-10, 2013
                                            4. MacDonald-Jankowski DS: Ossifying fibroma: a systematic review. Dentomaxillofac Radiol. 38(8):495-513, 2009
                                            5. Boudewyns AN et al: Sinonasal fibro-osseous hamartoma: case presentation and differential diagnosis with other fibro-osseous lesions involving the paranasal sinuses. Eur Arch Otorhinolaryngol. 263(3):276-81, 2006
                                            6. Eller R et al: Common fibro-osseous lesions of the paranasal sinuses. Otolaryngol Clin North Am. 39(3):585-600, x, 2006
                                            7. Mehta D et al: Paediatric fibro-osseous lesions of the nose and paranasal sinuses. Int J Pediatr Otorhinolaryngol. 70(2):193-9, 2006
                                            8. Kendi AT et al: Sinonasal ossifying fibroma with fluid-fluid levels on MR images. AJNR Am J Neuroradiol. 24(8):1639-41, 2003
                                            9. Alawi F: Benign fibro-osseous diseases of the maxillofacial bones. A review and differential diagnosis. Am J Clin Pathol. 118 Suppl:S50-70, 2002
                                            10. Khoury NJ et al: Juvenile ossifying fibroma: CT and MR findings. Eur Radiol. 12 Suppl 3:S109-13, 2002
                                            11. Williams HK et al: Juvenile ossifying fibroma. An analysis of eight cases and a comparison with other fibro-osseous lesions. J Oral Pathol Med. 29(1):13-8, 2000
                                            12. Engelbrecht V et al: CT and MRI of congenital sinonasal ossifying fibroma. Neuroradiology. 41(7):526-9, 1999
                                            13. Shand JM et al: Juvenile ossifying fibroma of the midface. J Craniofac Surg. 10(5):442-6, 1999
                                            14. Commins DJ et al: Fibrous dysplasia and ossifying fibroma of the paranasal sinuses. J Laryngol Otol. 112(10):964-8, 1998
                                            15. Lawton MT et al: Juvenile active ossifying fibroma. Report of four cases. J Neurosurg. 86(2):279-85, 1997
                                            16. Slootweg PJ: Maxillofacial fibro-osseous lesions: classification and differential diagnosis. Semin Diagn Pathol. 13(2):104-12, 1996
                                            17. Thompson J et al: Nasopharyngeal nonossifying variant of ossifying fibromyxoid tumor: CT and MR findings. AJNR Am J Neuroradiol. 16(5):1132-4, 1995
                                            18. Sterling KM et al: Ossifying fibroma of sphenoid bone with coexistent mucocele: CT and MRI. J Comput Assist Tomogr. 17(3):492-4, 1993
                                            19. Han MH et al: Sinonasal psammomatoid ossifying fibromas: CT and MR manifestations. AJNR Am J Neuroradiol. 12(1):25-30, 1991
                                            20. Marvel JB et al: Ossifying fibroma of the mid-face and paranasal sinuses: diagnostic and therapeutic considerations. Otolaryngol Head Neck Surg. 104(6):803-8, 1991
                                            Related Anatomy
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                                            Related Differential Diagnoses
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                                            References
                                            Tables

                                            Tables

                                            KEY FACTS

                                            • Terminology

                                              • Imaging

                                                • Top Differential Diagnoses

                                                  • Pathology

                                                    • Clinical Issues

                                                      TERMINOLOGY

                                                      • Abbreviations

                                                        • Ossifying fibroma (OsFib)
                                                      • Synonyms

                                                        • Cementoossifying fibroma, psammomatoid ossifying fibroma, juvenile-aggressive ossifying fibroma
                                                      • Definitions

                                                        • Benign fibroosseous lesion composed of encapsulated mixture of fibrous tissue & mature bone

                                                      IMAGING

                                                      • General Features

                                                        • CT Findings

                                                          • MR Findings

                                                            • Imaging Recommendations

                                                              DIFFERENTIAL DIAGNOSIS

                                                                PATHOLOGY

                                                                • General Features

                                                                  • Staging, Grading, & Classification

                                                                    • Gross Pathologic & Surgical Features

                                                                      • Microscopic Features

                                                                        CLINICAL ISSUES

                                                                        • Presentation

                                                                          • Demographics

                                                                            • Natural History & Prognosis

                                                                              • Treatment

                                                                                DIAGNOSTIC CHECKLIST

                                                                                • Consider

                                                                                  • Image Interpretation Pearls

                                                                                    • Reporting Tips

                                                                                      Selected References

                                                                                      1. Ciniglio Appiani M et al: Ossifying fibromas of the paranasal sinuses: diagnosis and management. Acta Otorhinolaryngol Ital. 35(5):355-61, 2015
                                                                                      2. MacDonald DS: Maxillofacial fibro-osseous lesions. Clin Radiol. 70(1):25-36, 2015
                                                                                      3. McCarthy EF: Fibro-osseous lesions of the maxillofacial bones. Head Neck Pathol. 7(1):5-10, 2013
                                                                                      4. MacDonald-Jankowski DS: Ossifying fibroma: a systematic review. Dentomaxillofac Radiol. 38(8):495-513, 2009
                                                                                      5. Boudewyns AN et al: Sinonasal fibro-osseous hamartoma: case presentation and differential diagnosis with other fibro-osseous lesions involving the paranasal sinuses. Eur Arch Otorhinolaryngol. 263(3):276-81, 2006
                                                                                      6. Eller R et al: Common fibro-osseous lesions of the paranasal sinuses. Otolaryngol Clin North Am. 39(3):585-600, x, 2006
                                                                                      7. Mehta D et al: Paediatric fibro-osseous lesions of the nose and paranasal sinuses. Int J Pediatr Otorhinolaryngol. 70(2):193-9, 2006
                                                                                      8. Kendi AT et al: Sinonasal ossifying fibroma with fluid-fluid levels on MR images. AJNR Am J Neuroradiol. 24(8):1639-41, 2003
                                                                                      9. Alawi F: Benign fibro-osseous diseases of the maxillofacial bones. A review and differential diagnosis. Am J Clin Pathol. 118 Suppl:S50-70, 2002
                                                                                      10. Khoury NJ et al: Juvenile ossifying fibroma: CT and MR findings. Eur Radiol. 12 Suppl 3:S109-13, 2002
                                                                                      11. Williams HK et al: Juvenile ossifying fibroma. An analysis of eight cases and a comparison with other fibro-osseous lesions. J Oral Pathol Med. 29(1):13-8, 2000
                                                                                      12. Engelbrecht V et al: CT and MRI of congenital sinonasal ossifying fibroma. Neuroradiology. 41(7):526-9, 1999
                                                                                      13. Shand JM et al: Juvenile ossifying fibroma of the midface. J Craniofac Surg. 10(5):442-6, 1999
                                                                                      14. Commins DJ et al: Fibrous dysplasia and ossifying fibroma of the paranasal sinuses. J Laryngol Otol. 112(10):964-8, 1998
                                                                                      15. Lawton MT et al: Juvenile active ossifying fibroma. Report of four cases. J Neurosurg. 86(2):279-85, 1997
                                                                                      16. Slootweg PJ: Maxillofacial fibro-osseous lesions: classification and differential diagnosis. Semin Diagn Pathol. 13(2):104-12, 1996
                                                                                      17. Thompson J et al: Nasopharyngeal nonossifying variant of ossifying fibromyxoid tumor: CT and MR findings. AJNR Am J Neuroradiol. 16(5):1132-4, 1995
                                                                                      18. Sterling KM et al: Ossifying fibroma of sphenoid bone with coexistent mucocele: CT and MRI. J Comput Assist Tomogr. 17(3):492-4, 1993
                                                                                      19. Han MH et al: Sinonasal psammomatoid ossifying fibromas: CT and MR manifestations. AJNR Am J Neuroradiol. 12(1):25-30, 1991
                                                                                      20. Marvel JB et al: Ossifying fibroma of the mid-face and paranasal sinuses: diagnostic and therapeutic considerations. Otolaryngol Head Neck Surg. 104(6):803-8, 1991