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Head and Neck
Diagnosis
Nose and Sinus
Malignant Tumors
Sinonasal Osteosarcoma
Sinonasal Osteosarcoma
Blair A. Winegar, MD
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KEY FACTS
Terminology
Imaging
Top Differential Diagnoses
Pathology
Clinical Issues
TERMINOLOGY
Abbreviations
Sinonasal osteosarcoma (OSa)
Definitions
Rare malignant bone tumor arising from primitive
bone-forming mesenchyma
IMAGING
General Features
Imaging Recommendations
Radiographic Findings
CT Findings
MR Findings
Nuclear Medicine Findings
DIFFERENTIAL DIAGNOSIS
PATHOLOGY
General Features
Staging, Grading, & Classification
Gross Pathologic & Surgical Features
Microscopic Features
CLINICAL ISSUES
Presentation
Demographics
Natural History & Prognosis
Treatment
DIAGNOSTIC CHECKLIST
Consider
Selected References
Fujiwara T et al: Second primary osteosarcomas in patients with retinoblastoma. Jpn J Clin Oncol. 45(12):1139-45, 2015
Amaral MB et al: Advanced osteosarcoma of the maxilla: a case report. Med Oral Patol Oral Cir Bucal. 13(8):E492-5, 2008
Franco GutiƩrrez V et al: Radiation-induced sarcomas of the head and neck. J Craniofac Surg. 19(5):1287-91, 2008
Jasnau S et al: Craniofacial osteosarcoma Experience of the cooperative German-Austrian-Swiss osteosarcoma study group. Oral Oncol. 44(3):286-94, 2008
Sargi Z et al: Pathology quiz case. Sinonasal osteosarcoma. Arch Otolaryngol Head Neck Surg. 134(12):1343, 1344, 2008
McHugh JB et al: Primary versus radiation-associated craniofacial osteosarcoma: Biologic and clinicopathologic comparisons. Cancer. 107(3):554-62, 2006
Tseng CC et al: Pathology quiz case 2. Postirradiation sinonasal osteosarcoma. Arch Otolaryngol Head Neck Surg. 131(2):173, 175-6, 2005
Nakamura T et al: Osteosarcoma metastatic to the mandible: a case report. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 91(4):452-4, 2001
Maes P et al: Primary and secondary osteosarcoma of the face: a rare childhood malignancy. Med Pediatr Oncol. 30(3):170-4, 1998
Related Anatomy
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Related Differential Diagnoses
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References
Tables
Tables
KEY FACTS
Terminology
Imaging
Top Differential Diagnoses
Pathology
Clinical Issues
TERMINOLOGY
Abbreviations
Sinonasal osteosarcoma (OSa)
Definitions
Rare malignant bone tumor arising from primitive
bone-forming mesenchyma
IMAGING
General Features
Imaging Recommendations
Radiographic Findings
CT Findings
MR Findings
Nuclear Medicine Findings
DIFFERENTIAL DIAGNOSIS
PATHOLOGY
General Features
Staging, Grading, & Classification
Gross Pathologic & Surgical Features
Microscopic Features
CLINICAL ISSUES
Presentation
Demographics
Natural History & Prognosis
Treatment
DIAGNOSTIC CHECKLIST
Consider
Selected References
Fujiwara T et al: Second primary osteosarcomas in patients with retinoblastoma. Jpn J Clin Oncol. 45(12):1139-45, 2015
Amaral MB et al: Advanced osteosarcoma of the maxilla: a case report. Med Oral Patol Oral Cir Bucal. 13(8):E492-5, 2008
Franco GutiƩrrez V et al: Radiation-induced sarcomas of the head and neck. J Craniofac Surg. 19(5):1287-91, 2008
Jasnau S et al: Craniofacial osteosarcoma Experience of the cooperative German-Austrian-Swiss osteosarcoma study group. Oral Oncol. 44(3):286-94, 2008
Sargi Z et al: Pathology quiz case. Sinonasal osteosarcoma. Arch Otolaryngol Head Neck Surg. 134(12):1343, 1344, 2008
McHugh JB et al: Primary versus radiation-associated craniofacial osteosarcoma: Biologic and clinicopathologic comparisons. Cancer. 107(3):554-62, 2006
Tseng CC et al: Pathology quiz case 2. Postirradiation sinonasal osteosarcoma. Arch Otolaryngol Head Neck Surg. 131(2):173, 175-6, 2005
Nakamura T et al: Osteosarcoma metastatic to the mandible: a case report. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 91(4):452-4, 2001
Maes P et al: Primary and secondary osteosarcoma of the face: a rare childhood malignancy. Med Pediatr Oncol. 30(3):170-4, 1998
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