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KEY FACTS
Terminology
Imaging
Top Differential Diagnoses
Clinical Issues
TERMINOLOGY
Abbreviations
- Rosai-Dorfman disease (RD)
Synonyms
- Sinus histiocytosis with massive lymphadenopathy
Definitions
- Rare, benign disorder characterized histologically by lymphatic sinus dilatation due to histiocyte proliferation
IMAGING
General Features
Imaging Recommendations
Ultrasonographic Findings
CT Findings
MR Findings
Nuclear Medicine Findings
DIFFERENTIAL DIAGNOSIS
PATHOLOGY
General Features
Microscopic Features
Immunohistochemical Features
CLINICAL ISSUES
Presentation
Demographics
Natural History & Prognosis
Treatment
DIAGNOSTIC CHECKLIST
Consider
Selected References
- Mar WA et al: Rosai-Dorfman disease: manifestations outside of the head and neck. AJR Am J Roentgenol. 208(4):721-732, 2017
- Louis DN et al: The 2016 World Health Organization Classification of Tumors of the Central Nervous System: a summary. Acta Neuropathol. 131(6):803-20, 2016
- McClellan SF et al: Orbital Rosai-Dorfman disease: a literature review. Orbit. 32(5):341-6, 2013
- Wimmer DB et al: Extranodal rosai-dorfman disease associated with increased numbers of immunoglobulin g4 plasma cells involving the colon: case report with literature review. Arch Pathol Lab Med. 137(7):999-1004, 2013
- Raslan OA et al: Rosai-Dorfman disease in neuroradiology: imaging findings in a series of 10 patients. AJR Am J Roentgenol. 196(2):W187-93, 2011
- La Barge DV 3rd et al: Sinus histiocytosis with massive lymphadenopathy (Rosai-Dorfman disease): imaging manifestations in the head and neck. AJR Am J Roentgenol. 191(6):W299-306, 2008
- Guven G et al: Rosai Dorfman disease of the parotid and submandibular glands: salivary gland scintigraphy and oral findings in two siblings. Dentomaxillofac Radiol. 36(7):428-33, 2007
- Louis DN et al: WHO Classification of Tumours of the Central Nervous System. 4th ed. Lyon: IARC Press, 2007
- Ottaviano G et al: Extranodal Rosai-Dorfman disease: involvement of eye, nose and trachea. Acta Otolaryngol. 126(6):657-60, 2006
- Lim R et al: FDG PET of Rosai-Dorfman disease of the thymus. AJR Am J Roentgenol. 182(2):514, 2004
- Yu JQ et al: Demonstration of increased FDG activity in Rosai-Dorfman disease on positron emission tomography. Clin Nucl Med. 29(3):209-10, 2004
- Wang E et al: Rosai-Dorfman disease presenting with isolated bilateral orbital masses: report of two cases. AJNR Am J Neuroradiol. 22(7):1386-8, 2001
- Carbone A et al: Review of sinus histiocytosis with massive lymphadenopathy (Rosai-Dorfman disease) of head and neck. Ann Otol Rhinol Laryngol. 108(11 Pt 1):1095-104, 1999
- McAlister WH et al: Sinus histiocytosis with massive lymphadenopathy (Rosai-Dorfman disease). Pediatr Radiol. 20(6):425-32, 1990
- Rosai J et al: Sinus histiocytosis with massive lymphadenopathy. A newly recognized benign clinicopathological entity. Arch Pathol. 87(1):63-70, 1969
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References
Tables
Tables
KEY FACTS
Terminology
Imaging
Top Differential Diagnoses
Clinical Issues
TERMINOLOGY
Abbreviations
- Rosai-Dorfman disease (RD)
Synonyms
- Sinus histiocytosis with massive lymphadenopathy
Definitions
- Rare, benign disorder characterized histologically by lymphatic sinus dilatation due to histiocyte proliferation
IMAGING
General Features
Imaging Recommendations
Ultrasonographic Findings
CT Findings
MR Findings
Nuclear Medicine Findings
DIFFERENTIAL DIAGNOSIS
PATHOLOGY
General Features
Microscopic Features
Immunohistochemical Features
CLINICAL ISSUES
Presentation
Demographics
Natural History & Prognosis
Treatment
DIAGNOSTIC CHECKLIST
Consider
Selected References
- Mar WA et al: Rosai-Dorfman disease: manifestations outside of the head and neck. AJR Am J Roentgenol. 208(4):721-732, 2017
- Louis DN et al: The 2016 World Health Organization Classification of Tumors of the Central Nervous System: a summary. Acta Neuropathol. 131(6):803-20, 2016
- McClellan SF et al: Orbital Rosai-Dorfman disease: a literature review. Orbit. 32(5):341-6, 2013
- Wimmer DB et al: Extranodal rosai-dorfman disease associated with increased numbers of immunoglobulin g4 plasma cells involving the colon: case report with literature review. Arch Pathol Lab Med. 137(7):999-1004, 2013
- Raslan OA et al: Rosai-Dorfman disease in neuroradiology: imaging findings in a series of 10 patients. AJR Am J Roentgenol. 196(2):W187-93, 2011
- La Barge DV 3rd et al: Sinus histiocytosis with massive lymphadenopathy (Rosai-Dorfman disease): imaging manifestations in the head and neck. AJR Am J Roentgenol. 191(6):W299-306, 2008
- Guven G et al: Rosai Dorfman disease of the parotid and submandibular glands: salivary gland scintigraphy and oral findings in two siblings. Dentomaxillofac Radiol. 36(7):428-33, 2007
- Louis DN et al: WHO Classification of Tumours of the Central Nervous System. 4th ed. Lyon: IARC Press, 2007
- Ottaviano G et al: Extranodal Rosai-Dorfman disease: involvement of eye, nose and trachea. Acta Otolaryngol. 126(6):657-60, 2006
- Lim R et al: FDG PET of Rosai-Dorfman disease of the thymus. AJR Am J Roentgenol. 182(2):514, 2004
- Yu JQ et al: Demonstration of increased FDG activity in Rosai-Dorfman disease on positron emission tomography. Clin Nucl Med. 29(3):209-10, 2004
- Wang E et al: Rosai-Dorfman disease presenting with isolated bilateral orbital masses: report of two cases. AJNR Am J Neuroradiol. 22(7):1386-8, 2001
- Carbone A et al: Review of sinus histiocytosis with massive lymphadenopathy (Rosai-Dorfman disease) of head and neck. Ann Otol Rhinol Laryngol. 108(11 Pt 1):1095-104, 1999
- McAlister WH et al: Sinus histiocytosis with massive lymphadenopathy (Rosai-Dorfman disease). Pediatr Radiol. 20(6):425-32, 1990
- Rosai J et al: Sinus histiocytosis with massive lymphadenopathy. A newly recognized benign clinicopathological entity. Arch Pathol. 87(1):63-70, 1969
