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Sjögren Syndrome
Carmen C. Cho, MBBS, FRCREvelyn W. K. Tang, MBBS, FRCRAnil T. Ahuja, MD, FRCR
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KEY FACTS

  • Imaging

    • Top Differential Diagnoses

      • Diagnostic Checklist

        TERMINOLOGY

        • Abbreviations

          • Sjögren syndrome (SjS)
        • Synonyms

          • Sicca syndrome
        • Definitions

          • Chronic systemic autoimmune exocrinopathy that causes salivary and lacrimal gland tissue destruction
            • Primary: Dry eyes and mouth with no collagen vascular disease (CVD)
            • Secondary: Dry eyes and mouth with CVD, most commonly rheumatoid arthritis

        IMAGING

        • General Features

          • Ultrasonographic Findings

            • CT Findings

              • MR Findings

                • Imaging Recommendations

                  DIFFERENTIAL DIAGNOSIS

                    PATHOLOGY

                    • General Features

                      • Staging, Grading, & Classification

                        • Gross Pathologic & Surgical Features

                          • Microscopic Features

                            CLINICAL ISSUES

                            • Presentation

                              • Demographics

                                • Natural History & Prognosis

                                  • Treatment

                                    DIAGNOSTIC CHECKLIST

                                    • Image Interpretation Pearls

                                      Selected References

                                      1. Fisher BA et al: Effect of rituximab on a salivary gland ultrasound score in primary Sjögren's syndrome: results of the TRACTISS randomised double-blind multicentre substudy. Ann Rheum Dis. 77(3):412-416, 2018
                                      Related Anatomy
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                                      Related Differential Diagnoses
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                                      References
                                      Tables

                                      Tables

                                      KEY FACTS

                                      • Imaging

                                        • Top Differential Diagnoses

                                          • Diagnostic Checklist

                                            TERMINOLOGY

                                            • Abbreviations

                                              • Sjögren syndrome (SjS)
                                            • Synonyms

                                              • Sicca syndrome
                                            • Definitions

                                              • Chronic systemic autoimmune exocrinopathy that causes salivary and lacrimal gland tissue destruction
                                                • Primary: Dry eyes and mouth with no collagen vascular disease (CVD)
                                                • Secondary: Dry eyes and mouth with CVD, most commonly rheumatoid arthritis

                                            IMAGING

                                            • General Features

                                              • Ultrasonographic Findings

                                                • CT Findings

                                                  • MR Findings

                                                    • Imaging Recommendations

                                                      DIFFERENTIAL DIAGNOSIS

                                                        PATHOLOGY

                                                        • General Features

                                                          • Staging, Grading, & Classification

                                                            • Gross Pathologic & Surgical Features

                                                              • Microscopic Features

                                                                CLINICAL ISSUES

                                                                • Presentation

                                                                  • Demographics

                                                                    • Natural History & Prognosis

                                                                      • Treatment

                                                                        DIAGNOSTIC CHECKLIST

                                                                        • Image Interpretation Pearls

                                                                          Selected References

                                                                          1. Fisher BA et al: Effect of rituximab on a salivary gland ultrasound score in primary Sjögren's syndrome: results of the TRACTISS randomised double-blind multicentre substudy. Ann Rheum Dis. 77(3):412-416, 2018