Chronic systemic autoimmune exocrinopathy that causes salivary and lacrimal gland tissue destruction
Primary: Dry eyes and mouth with no collagen vascular disease (CVD)
Secondary: Dry eyes and mouth with CVD, most commonly rheumatoid arthritis
IMAGING
General Features
Ultrasonographic Findings
CT Findings
MR Findings
Imaging Recommendations
DIFFERENTIAL DIAGNOSIS
PATHOLOGY
General Features
Staging, Grading, & Classification
Gross Pathologic & Surgical Features
Microscopic Features
CLINICAL ISSUES
Presentation
Demographics
Natural History & Prognosis
Treatment
DIAGNOSTIC CHECKLIST
Image Interpretation Pearls
Selected References
Fisher BA et al: Effect of rituximab on a salivary gland ultrasound score in primary Sjögren's syndrome: results of the TRACTISS randomised double-blind multicentre substudy. Ann Rheum Dis. 77(3):412-416, 2018
Related Anatomy
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Related Differential Diagnoses
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References
Tables
Tables
KEY FACTS
Imaging
Top Differential Diagnoses
Diagnostic Checklist
TERMINOLOGY
Abbreviations
Sjögren syndrome (SjS)
Synonyms
Sicca syndrome
Definitions
Chronic systemic autoimmune exocrinopathy that causes salivary and lacrimal gland tissue destruction
Primary: Dry eyes and mouth with no collagen vascular disease (CVD)
Secondary: Dry eyes and mouth with CVD, most commonly rheumatoid arthritis
IMAGING
General Features
Ultrasonographic Findings
CT Findings
MR Findings
Imaging Recommendations
DIFFERENTIAL DIAGNOSIS
PATHOLOGY
General Features
Staging, Grading, & Classification
Gross Pathologic & Surgical Features
Microscopic Features
CLINICAL ISSUES
Presentation
Demographics
Natural History & Prognosis
Treatment
DIAGNOSTIC CHECKLIST
Image Interpretation Pearls
Selected References
Fisher BA et al: Effect of rituximab on a salivary gland ultrasound score in primary Sjögren's syndrome: results of the TRACTISS randomised double-blind multicentre substudy. Ann Rheum Dis. 77(3):412-416, 2018
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