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Skeletal Metastases, Chest Wall
Santiago Martínez-Jiménez, MD
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KEY FACTS

  • Terminology

    • Imaging

      • Top Differential Diagnoses

        • Clinical Issues

          TERMINOLOGY

          • Definitions

            • Skeleton involvement by malignancy
            • Routes of spread: Direct, hematogenous, lymphatic

          IMAGING

          • General Features

            • Radiographic Findings

              • CT Findings

                • MR Findings

                  • Nuclear Medicine Findings

                    DIFFERENTIAL DIAGNOSIS

                      PATHOLOGY

                      • General Features

                        CLINICAL ISSUES

                        • Presentation

                          • Natural History & Prognosis

                            • Treatment

                              Selected References

                              1. Oldan JD et al: Ivory vertebra on 18F-sodium fluoride scan: an old sign in a new modality. Clin Nucl Med. 39(11):972-4, 2014
                              2. Al-Nabhani K et al: Flare response versus disease progression in patients with non-small cell lung cancer. J Radiol Case Rep. 6(11):34-42, 2012
                              3. Messiou C et al: The CT flare response of metastatic bone disease in prostate cancer. Acta Radiol. 52(5):557-61, 2011
                              4. Ansén S et al: Osteoblastic response in patients with non-small cell lung cancer with activating EGFR Mutations and bone metastases during treatment with EGFR kinase inhibitors. J Thorac Oncol. 5(3):407-9, 2010
                              5. Lind JS et al: Osteoblastic bone lesions developing during treatment with erlotinib indicate major response in patients with non-small cell lung cancer: a brief report. J Thorac Oncol. 5(4):554-7, 2010
                              6. Georgy BA: Metastatic spinal lesions: state-of-the-art treatment options and future trends. AJNR Am J Neuroradiol. 29(9):1605-11, 2008
                              7. Wade AA et al: Flare response in 18F-fluoride ion PET bone scanning. AJR Am J Roentgenol. 186(6):1783-6, 2006
                              8. Graham TS. The Ivory Vertebra Sign. Radiology. 235:614-615, 2005
                              9. Taneichi H et al: Risk factors and probability of vertebral body collapse in metastases of the thoracic and lumbar spine. Spine (Phila Pa 1976). 22(3):239-45, 1997
                              10. Coleman RE et al: Bone scan flare predicts successful systemic therapy for bone metastases. J Nucl Med. 29(8):1354-9, 1988
                              Related Anatomy
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                              Related Differential Diagnoses
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                              References
                              Tables

                              Tables

                              KEY FACTS

                              • Terminology

                                • Imaging

                                  • Top Differential Diagnoses

                                    • Clinical Issues

                                      TERMINOLOGY

                                      • Definitions

                                        • Skeleton involvement by malignancy
                                        • Routes of spread: Direct, hematogenous, lymphatic

                                      IMAGING

                                      • General Features

                                        • Radiographic Findings

                                          • CT Findings

                                            • MR Findings

                                              • Nuclear Medicine Findings

                                                DIFFERENTIAL DIAGNOSIS

                                                  PATHOLOGY

                                                  • General Features

                                                    CLINICAL ISSUES

                                                    • Presentation

                                                      • Natural History & Prognosis

                                                        • Treatment

                                                          Selected References

                                                          1. Oldan JD et al: Ivory vertebra on 18F-sodium fluoride scan: an old sign in a new modality. Clin Nucl Med. 39(11):972-4, 2014
                                                          2. Al-Nabhani K et al: Flare response versus disease progression in patients with non-small cell lung cancer. J Radiol Case Rep. 6(11):34-42, 2012
                                                          3. Messiou C et al: The CT flare response of metastatic bone disease in prostate cancer. Acta Radiol. 52(5):557-61, 2011
                                                          4. Ansén S et al: Osteoblastic response in patients with non-small cell lung cancer with activating EGFR Mutations and bone metastases during treatment with EGFR kinase inhibitors. J Thorac Oncol. 5(3):407-9, 2010
                                                          5. Lind JS et al: Osteoblastic bone lesions developing during treatment with erlotinib indicate major response in patients with non-small cell lung cancer: a brief report. J Thorac Oncol. 5(4):554-7, 2010
                                                          6. Georgy BA: Metastatic spinal lesions: state-of-the-art treatment options and future trends. AJNR Am J Neuroradiol. 29(9):1605-11, 2008
                                                          7. Wade AA et al: Flare response in 18F-fluoride ion PET bone scanning. AJR Am J Roentgenol. 186(6):1783-6, 2006
                                                          8. Graham TS. The Ivory Vertebra Sign. Radiology. 235:614-615, 2005
                                                          9. Taneichi H et al: Risk factors and probability of vertebral body collapse in metastases of the thoracic and lumbar spine. Spine (Phila Pa 1976). 22(3):239-45, 1997
                                                          10. Coleman RE et al: Bone scan flare predicts successful systemic therapy for bone metastases. J Nucl Med. 29(8):1354-9, 1988