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Gynecology
Diagnosis
Vagina and Vulva
Lower Genital Cysts
Skene Gland Cyst
Skene Gland Cyst
Marc S. Tubay, MD; Akram M. Shaaban, MBBCh
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KEY FACTS

  • Terminology

    • Imaging

      • Top Differential Diagnoses

        • Clinical Issues

          • Diagnostic Checklist

            TERMINOLOGY

            • Synonyms

              • Distal paraurethral gland cyst

            • Definitions

              • Cystic dilation of Skene glands secondary to ductal obstruction/stricturing

            IMAGING

            • General Features

              • CT Findings

                • MR Findings

                  • Ultrasonographic Findings

                    • Imaging Recommendations

                      DIFFERENTIAL DIAGNOSIS

                        PATHOLOGY

                        • General Features

                          • Gross Pathologic & Surgical Features

                            • Microscopic Features

                              • Etiology

                                CLINICAL ISSUES

                                • Presentation

                                  • Demographics

                                    • Natural History & Prognosis

                                      • Treatment

                                        DIAGNOSTIC CHECKLIST

                                        • Consider

                                          • Image Interpretation Pearls

                                            • Reporting Tips

                                              Selected References

                                              1. Kaufman ME et al: Skene's gland adenocarcinoma: borrowing from prostate cancer experience for the evaluation and management of a rare malignancy. Urology. 151:182-7, 2020
                                              2. Itani M et al: MRI of female urethra and periurethral pathologies. Int Urogynecol J. 27(2):195-204, 2016
                                              3. Hosseinzadeh K et al: Imaging of the female perineum in adults. Radiographics. 32(4):E129-68, 2012
                                              4. Walker DK et al: Overlooked diseases of the vagina: a directed anatomic-pathologic approach for imaging assessment. Radiographics. 31(6):1583-98, 2011
                                              5. Busto Martín L et al: Cyst of the skene's gland: report of four cases and bibliographic review. Arch Esp Urol. 63(3):238-42, 2010
                                              6. Chaudhari VV et al: MR imaging and US of female urethral and periurethral disease. Radiographics. 30(7):1857-74, 2010
                                              7. Chong Y et al: Adenofibroma of skene's duct: a case report. Patholog Res Int. 2010:318973, 2010
                                              8. Fletcher SG et al: Differential diagnosis of chronic pelvic pain in women: the urologist's approach. Nat Rev Urol. 6(10):557-62, 2009
                                              9. Prasad SR et al: Cross-sectional imaging of the female urethra: technique and results. Radiographics. 25(3):749-61, 2005
                                              10. Pongtippan A et al: Skene's gland adenocarcinoma resembling prostatic adenocarcinoma. Int J Gynecol Pathol. 23(1):71-4, 2004
                                              11. Eilber KS et al: Benign cystic lesions of the vagina: a literature review. J Urol. 170(3):717-22, 2003
                                              12. Ceylan H et al: Paraurethral cyst: is conservative management always appropriate? Eur J Pediatr Surg. 12(3):212-4, 2002
                                              13. Dodson MK et al: Skene's gland adenocarcinoma with increased serum level of prostate-specific antigen. Gynecol Oncol. 55(2):304-7, 1994
                                              14. Lee NH et al: Skene's duct cysts in female newborns. J Pediatr Surg. 27(1):15-7, 1992
                                              Related Anatomy
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                                              Related Differential Diagnoses
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                                              References
                                              Tables

                                              Tables

                                              KEY FACTS

                                              • Terminology

                                                • Imaging

                                                  • Top Differential Diagnoses

                                                    • Clinical Issues

                                                      • Diagnostic Checklist

                                                        TERMINOLOGY

                                                        • Synonyms

                                                          • Distal paraurethral gland cyst

                                                        • Definitions

                                                          • Cystic dilation of Skene glands secondary to ductal obstruction/stricturing

                                                        IMAGING

                                                        • General Features

                                                          • CT Findings

                                                            • MR Findings

                                                              • Ultrasonographic Findings

                                                                • Imaging Recommendations

                                                                  DIFFERENTIAL DIAGNOSIS

                                                                    PATHOLOGY

                                                                    • General Features

                                                                      • Gross Pathologic & Surgical Features

                                                                        • Microscopic Features

                                                                          • Etiology

                                                                            CLINICAL ISSUES

                                                                            • Presentation

                                                                              • Demographics

                                                                                • Natural History & Prognosis

                                                                                  • Treatment

                                                                                    DIAGNOSTIC CHECKLIST

                                                                                    • Consider

                                                                                      • Image Interpretation Pearls

                                                                                        • Reporting Tips

                                                                                          Selected References

                                                                                          1. Kaufman ME et al: Skene's gland adenocarcinoma: borrowing from prostate cancer experience for the evaluation and management of a rare malignancy. Urology. 151:182-7, 2020
                                                                                          2. Itani M et al: MRI of female urethra and periurethral pathologies. Int Urogynecol J. 27(2):195-204, 2016
                                                                                          3. Hosseinzadeh K et al: Imaging of the female perineum in adults. Radiographics. 32(4):E129-68, 2012
                                                                                          4. Walker DK et al: Overlooked diseases of the vagina: a directed anatomic-pathologic approach for imaging assessment. Radiographics. 31(6):1583-98, 2011
                                                                                          5. Busto Martín L et al: Cyst of the skene's gland: report of four cases and bibliographic review. Arch Esp Urol. 63(3):238-42, 2010
                                                                                          6. Chaudhari VV et al: MR imaging and US of female urethral and periurethral disease. Radiographics. 30(7):1857-74, 2010
                                                                                          7. Chong Y et al: Adenofibroma of skene's duct: a case report. Patholog Res Int. 2010:318973, 2010
                                                                                          8. Fletcher SG et al: Differential diagnosis of chronic pelvic pain in women: the urologist's approach. Nat Rev Urol. 6(10):557-62, 2009
                                                                                          9. Prasad SR et al: Cross-sectional imaging of the female urethra: technique and results. Radiographics. 25(3):749-61, 2005
                                                                                          10. Pongtippan A et al: Skene's gland adenocarcinoma resembling prostatic adenocarcinoma. Int J Gynecol Pathol. 23(1):71-4, 2004
                                                                                          11. Eilber KS et al: Benign cystic lesions of the vagina: a literature review. J Urol. 170(3):717-22, 2003
                                                                                          12. Ceylan H et al: Paraurethral cyst: is conservative management always appropriate? Eur J Pediatr Surg. 12(3):212-4, 2002
                                                                                          13. Dodson MK et al: Skene's gland adenocarcinoma with increased serum level of prostate-specific antigen. Gynecol Oncol. 55(2):304-7, 1994
                                                                                          14. Lee NH et al: Skene's duct cysts in female newborns. J Pediatr Surg. 27(1):15-7, 1992