Findings related to skin; may mimic breast parenchymal lesions on imaging
Most common: Epidermal inclusion cyst, sebaceous cyst, and dermal Ca⁺⁺, considered separately
Entities may be isolated, neoplastic, extensions of diffuse cutaneous abnormalities, manifestation of systemic processes, iatrogenic, or traumatic
IMAGING
General Features
Mammographic Findings
Ultrasonographic Findings
MR Findings
Nuclear Medicine Findings
Imaging Recommendations
DIFFERENTIAL DIAGNOSIS
CLINICAL ISSUES
Natural History & Prognosis
Treatment
DIAGNOSTIC CHECKLIST
Consider
Selected References
Lee CI et al: Breast Imaging Rotations in Radiology. New York: Oxford University Press. 394-402, 2018
Requena L et al: Cutaneous Adnexal Neoplasms. Switzerland: Springer. 2017
Orta LY et al: Cutaneous/subcutaneous mesenchymal proliferations of the breast. Semin Diagn Pathol. 34(5):470-478, 2017
Shin SJ. A Comprehensive Guide to Core Needle Biopsies of the Breast. Switzerland: Springer. 853-908, 2016
Rosen PP et al: Rosen's Breast Pathology. 4th ed. Philadelphia: Lippincott Williams & Wilkins. 1217-1237, 2014
Benveniste AP et al: Benign breast lesions detected by positron emission tomography-computed tomography. Eur J Radiol. 83(6):919-929, 2014
Cao MM et al: Mammographic signs of systemic disease. Radiographics. 31(4):1085-100, 2011
Giess CS et al: Distinguishing breast skin lesions from superficial breast parenchymal lesions: diagnostic criteria, imaging characteristics, and pitfalls. Radiographics. 31(7):1959-72, 2011
Kalli S et al: Lesions of the skin and superficial tissue at breast MR imaging. Radiographics. 30(7):1891-913, 2010
Alsaad KO et al: Skin adnexal neoplasms--part 1: an approach to tumours of the pilosebaceous unit. J Clin Pathol. 60(2):129-44, 2007
Obaidat NA et al: Skin adnexal neoplasms--part 2: an approach to tumours of cutaneous sweat glands. J Clin Pathol. 60(2):145-59, 2007
Kurul S et al: Different manifestations of malignant melanoma in the breast: a report of 12 cases and a review of the literature. Jpn J Clin Oncol. 35(4):202-6, 2005
Millman SL et al: An unusual presentation of neurofibromatosis of the breast. Breast J. 10(1):45-7, 2004
Murat A et al: Neurofibroma of the breast in a boy with neurofibromatosis type 1. Clin Imaging. 28(6):415-7, 2004
Wilson CH et al: Gynaecomastia, neurofibromatosis and breast cancer. Breast. 13(1):77-9, 2004
Park KY et al: Steatocystoma multiplex: mammographic and sonographic manifestations. AJR Am J Roentgenol. 180(1):271-4, 2003
Operé E et al: Localized scleroderma of the breast. Eur Radiol. 12(6):1483-5, 2002
Rosen PP: Rosen's Breast Pathology. 2nd ed. Philadelphia: Lippincott williams & Wilkins. 904-12, 2001
Shetty MK et al: Mondor's disease of the breast: sonographic and mammographic findings. AJR Am J Roentgenol. 177(4):893-6, 2001
Bassett LW et al: Diagnosis of Diseases of the Breast. Philadelphia: WB Saunders Co. 38-364, 1997
Denison CM et al: Epidermal inclusion cysts of the breast: three lesions with calcifications. Radiology. 204(2):493-6, 1997
Related Anatomy
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Related Differential Diagnoses
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References
Tables
Tables
KEY FACTS
Terminology
Imaging
Top Differential Diagnoses
TERMINOLOGY
Definitions
Findings related to skin; may mimic breast parenchymal lesions on imaging
Most common: Epidermal inclusion cyst, sebaceous cyst, and dermal Ca⁺⁺, considered separately
Entities may be isolated, neoplastic, extensions of diffuse cutaneous abnormalities, manifestation of systemic processes, iatrogenic, or traumatic
IMAGING
General Features
Mammographic Findings
Ultrasonographic Findings
MR Findings
Nuclear Medicine Findings
Imaging Recommendations
DIFFERENTIAL DIAGNOSIS
CLINICAL ISSUES
Natural History & Prognosis
Treatment
DIAGNOSTIC CHECKLIST
Consider
Selected References
Lee CI et al: Breast Imaging Rotations in Radiology. New York: Oxford University Press. 394-402, 2018
Requena L et al: Cutaneous Adnexal Neoplasms. Switzerland: Springer. 2017
Orta LY et al: Cutaneous/subcutaneous mesenchymal proliferations of the breast. Semin Diagn Pathol. 34(5):470-478, 2017
Shin SJ. A Comprehensive Guide to Core Needle Biopsies of the Breast. Switzerland: Springer. 853-908, 2016
Rosen PP et al: Rosen's Breast Pathology. 4th ed. Philadelphia: Lippincott Williams & Wilkins. 1217-1237, 2014
Benveniste AP et al: Benign breast lesions detected by positron emission tomography-computed tomography. Eur J Radiol. 83(6):919-929, 2014
Cao MM et al: Mammographic signs of systemic disease. Radiographics. 31(4):1085-100, 2011
Giess CS et al: Distinguishing breast skin lesions from superficial breast parenchymal lesions: diagnostic criteria, imaging characteristics, and pitfalls. Radiographics. 31(7):1959-72, 2011
Kalli S et al: Lesions of the skin and superficial tissue at breast MR imaging. Radiographics. 30(7):1891-913, 2010
Alsaad KO et al: Skin adnexal neoplasms--part 1: an approach to tumours of the pilosebaceous unit. J Clin Pathol. 60(2):129-44, 2007
Obaidat NA et al: Skin adnexal neoplasms--part 2: an approach to tumours of cutaneous sweat glands. J Clin Pathol. 60(2):145-59, 2007
Kurul S et al: Different manifestations of malignant melanoma in the breast: a report of 12 cases and a review of the literature. Jpn J Clin Oncol. 35(4):202-6, 2005
Millman SL et al: An unusual presentation of neurofibromatosis of the breast. Breast J. 10(1):45-7, 2004
Murat A et al: Neurofibroma of the breast in a boy with neurofibromatosis type 1. Clin Imaging. 28(6):415-7, 2004
Wilson CH et al: Gynaecomastia, neurofibromatosis and breast cancer. Breast. 13(1):77-9, 2004
Park KY et al: Steatocystoma multiplex: mammographic and sonographic manifestations. AJR Am J Roentgenol. 180(1):271-4, 2003
Operé E et al: Localized scleroderma of the breast. Eur Radiol. 12(6):1483-5, 2002
Rosen PP: Rosen's Breast Pathology. 2nd ed. Philadelphia: Lippincott williams & Wilkins. 904-12, 2001
Shetty MK et al: Mondor's disease of the breast: sonographic and mammographic findings. AJR Am J Roentgenol. 177(4):893-6, 2001
Bassett LW et al: Diagnosis of Diseases of the Breast. Philadelphia: WB Saunders Co. 38-364, 1997
Denison CM et al: Epidermal inclusion cysts of the breast: three lesions with calcifications. Radiology. 204(2):493-6, 1997
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