Congenital disorder with defect in osteoblastic differentiation and maturation, resulting in progressive replacement of normal cancellous bone by mixture of fibrous tissue and immature woven bone
IMAGING
General Features
Radiographic Findings
CT Findings
MR Findings
Nuclear Medicine Findings
Imaging Recommendations
DIFFERENTIAL DIAGNOSIS
PATHOLOGY
General Features
Staging, Grading, & Classification
Gross Pathologic & Surgical Features
Microscopic Features
CLINICAL ISSUES
Presentation
Demographics
Natural History & Prognosis
Treatment
DIAGNOSTIC CHECKLIST
Image Interpretation Pearls
Selected References
Chapurlat R et al: Bisphosphonates for the treatment of fibrous dysplasia of bone. 143:115784, 2021
Chattopadhyay A et al: Craniofacial fibrous dysplasia. J Clin Rheumatol. 26(7):e214, 2020
Davidova LA et al: An analysis of clinical and histopathologic features of fibrous dysplasia of the jaws: a series of 40 cases and review of literature. Head Neck Pathol. 14(2):353-61, 2020
Hwang D et al: Radiographic follow-up of fibrous dysplasia in 138 patients. AJR Am J Roentgenol. 215(6):1430-5, 2020
Lee SE et al: The diagnostic utility of the GNAS mutation in patients with fibrous dysplasia: meta-analysis of 168 sporadic cases. Hum Pathol. 43(8):1234-42, 2012
Wei YT et al: Fibrous dysplasia of skull. J Craniofac Surg. 21(2):538-42, 2010
Lisle DA et al: Imaging of craniofacial fibrous dysplasia. J Med Imaging Radiat Oncol. 52(4):325-32, 2008
Hullar TE et al: Paget's disease and fibrous dysplasia. Otolaryngol Clin North Am. 36(4):707-32, 2003
Chong VF et al: Fibrous dysplasia involving the base of the skull. AJR Am J Roentgenol. 178(3):717-20, 2002
Itshayek E et al: Fibrous dysplasia in combination with aneurysmal bone cyst of the occipital bone and the clivus: case report and review of the literature. Neurosurgery. 51(3):815-7; discussion 817-8, 2002
Sharma RR et al: Symptomatic cranial fibrous dysplasias: clinico-radiological analysis in a series of eight operative cases with follow-up results. J Clin Neurosci. 9(4):381-90, 2002
Sirvanci M et al: Monostotic fibrous dysplasia of the clivus: MRI and CT findings. Neuroradiology. 44(10):847-50, 2002
Tsuyuguchi N et al: Magnetic resonance imaging and [11C]methyl-L-methionine positron emission tomography of fibrous dysplasia--two case reports. Neurol Med Chir (Tokyo). 42(8):341-5, 2002
Lustig LR et al: Fibrous dysplasia involving the skull base and temporal bone. Arch Otolaryngol Head Neck Surg. 127(10):1239-47, 2001
Haddad GF et al: Concomitant fibrous dysplasia and aneurysmal bone cyst of the skull base. Case report and review of the literature. Pediatr Neurosurg. 28(3):147-53, 1998
Ham DW et al: Fibrous dysplasia of the clivus and sphenoid sinus. Mil Med. 163(3):186-9, 1998
Jee WH et al: Fibrous dysplasia: MR imaging characteristics with radiopathologic correlation. AJR Am J Roentgenol. 167(6):1523-7, 1996
Congenital disorder with defect in osteoblastic differentiation and maturation, resulting in progressive replacement of normal cancellous bone by mixture of fibrous tissue and immature woven bone
IMAGING
General Features
Radiographic Findings
CT Findings
MR Findings
Nuclear Medicine Findings
Imaging Recommendations
DIFFERENTIAL DIAGNOSIS
PATHOLOGY
General Features
Staging, Grading, & Classification
Gross Pathologic & Surgical Features
Microscopic Features
CLINICAL ISSUES
Presentation
Demographics
Natural History & Prognosis
Treatment
DIAGNOSTIC CHECKLIST
Image Interpretation Pearls
Selected References
Chapurlat R et al: Bisphosphonates for the treatment of fibrous dysplasia of bone. 143:115784, 2021
Chattopadhyay A et al: Craniofacial fibrous dysplasia. J Clin Rheumatol. 26(7):e214, 2020
Davidova LA et al: An analysis of clinical and histopathologic features of fibrous dysplasia of the jaws: a series of 40 cases and review of literature. Head Neck Pathol. 14(2):353-61, 2020
Hwang D et al: Radiographic follow-up of fibrous dysplasia in 138 patients. AJR Am J Roentgenol. 215(6):1430-5, 2020
Lee SE et al: The diagnostic utility of the GNAS mutation in patients with fibrous dysplasia: meta-analysis of 168 sporadic cases. Hum Pathol. 43(8):1234-42, 2012
Wei YT et al: Fibrous dysplasia of skull. J Craniofac Surg. 21(2):538-42, 2010
Lisle DA et al: Imaging of craniofacial fibrous dysplasia. J Med Imaging Radiat Oncol. 52(4):325-32, 2008
Hullar TE et al: Paget's disease and fibrous dysplasia. Otolaryngol Clin North Am. 36(4):707-32, 2003
Chong VF et al: Fibrous dysplasia involving the base of the skull. AJR Am J Roentgenol. 178(3):717-20, 2002
Itshayek E et al: Fibrous dysplasia in combination with aneurysmal bone cyst of the occipital bone and the clivus: case report and review of the literature. Neurosurgery. 51(3):815-7; discussion 817-8, 2002
Sharma RR et al: Symptomatic cranial fibrous dysplasias: clinico-radiological analysis in a series of eight operative cases with follow-up results. J Clin Neurosci. 9(4):381-90, 2002
Sirvanci M et al: Monostotic fibrous dysplasia of the clivus: MRI and CT findings. Neuroradiology. 44(10):847-50, 2002
Tsuyuguchi N et al: Magnetic resonance imaging and [11C]methyl-L-methionine positron emission tomography of fibrous dysplasia--two case reports. Neurol Med Chir (Tokyo). 42(8):341-5, 2002
Lustig LR et al: Fibrous dysplasia involving the skull base and temporal bone. Arch Otolaryngol Head Neck Surg. 127(10):1239-47, 2001
Haddad GF et al: Concomitant fibrous dysplasia and aneurysmal bone cyst of the skull base. Case report and review of the literature. Pediatr Neurosurg. 28(3):147-53, 1998
Ham DW et al: Fibrous dysplasia of the clivus and sphenoid sinus. Mil Med. 163(3):186-9, 1998
Jee WH et al: Fibrous dysplasia: MR imaging characteristics with radiopathologic correlation. AJR Am J Roentgenol. 167(6):1523-7, 1996
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