Metastatic disease affecting osseous skull base &/or adjacent soft tissue structures, including dura
IMAGING
General Features
Imaging Recommendations
CT Findings
MR Findings
Nuclear Medicine Findings
DIFFERENTIAL DIAGNOSIS
PATHOLOGY
General Features
Gross Pathologic & Surgical Features
CLINICAL ISSUES
Presentation
Demographics
Natural History & Prognosis
Treatment
DIAGNOSTIC CHECKLIST
Consider
Image Interpretation Pearls
Reporting Tips
Selected References
Ng S et al: Current status and treatment modalities in metastases to the pituitary: a systematic review. J Neurooncol. 146(2):219-27, 2020
Patel KR et al: Extended Survival After Surgical Resection for Pituitary Metastases: Clinical Features, Management, and Outcomes of Metastatic Disease to the Sella. Oncologist. ePub, 2019
Harrison RA et al: Intracranial dural, calvarial, and skull base metastases. Handb Clin Neurol. 149:205-25, 2018
Mendez JS et al: Metastatic complications of cancer involving the central and peripheral nervous systems. Neurol Clin. 36(3):579-98, 2018
Bag AK et al: Neuroimaging: intrinsic lesions of the central skull base region. Semin Ultrasound CT MR. 34(5):412-35, 2013
Chamoun RB et al: Management of skull base metastases. Neurosurg Clin N Am. 22(1):61-6, vi-ii, 2011
Mitsuya K et al: Metastatic skull tumors: MRI features and a new conventional classification. J Neurooncol. 104(1):239-45, 2011
Nayak L et al: Intracranial dural metastases. Cancer. 115(9):1947-53, 2009
Pallini R et al: Clivus metastases: report of seven patients and literature review. Acta Neurochir (Wien). 151(4):291-6; discussion 296, 2009
Nemeth AJ et al: Improved detection of skull metastasis with diffusion-weighted MR imaging. AJNR Am J Neuroradiol. 28(6):1088-92, 2007
Quattrocchi CC et al: Bone metastases in breast cancer: higher prevalence of osteosclerotic lesions. Radiol Med. 112(7):1049-59, 2007
Laigle-Donadey F et al: Skull-base metastases. J Neurooncol. 75(1):63-9, 2005
Maroldi R et al: Metastatic disease of the brain: extra-axial metastases (skull, dura, leptomeningeal) and tumour spread. Eur Radiol. 15(3):617-26, 2005
Stark AM et al: Skull metastases: clinical features, differential diagnosis, and review of the literature. Surg Neurol. 60(3):219-25; discussion 225-6, 2003
Gloria-Cruz TI et al: Metastases to temporal bones from primary nonsystemic malignant neoplasms. Arch Otolaryngol Head Neck Surg. 126(2):209-14, 2000
Sze G et al: MR imaging of the cranial meninges with emphasis on contrast enhancement and meningeal carcinomatosis. AJR Am J Roentgenol. 153(5):1039-49, 1989
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KEY FACTS
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TERMINOLOGY
Definitions
Metastatic disease affecting osseous skull base &/or adjacent soft tissue structures, including dura
IMAGING
General Features
Imaging Recommendations
CT Findings
MR Findings
Nuclear Medicine Findings
DIFFERENTIAL DIAGNOSIS
PATHOLOGY
General Features
Gross Pathologic & Surgical Features
CLINICAL ISSUES
Presentation
Demographics
Natural History & Prognosis
Treatment
DIAGNOSTIC CHECKLIST
Consider
Image Interpretation Pearls
Reporting Tips
Selected References
Ng S et al: Current status and treatment modalities in metastases to the pituitary: a systematic review. J Neurooncol. 146(2):219-27, 2020
Patel KR et al: Extended Survival After Surgical Resection for Pituitary Metastases: Clinical Features, Management, and Outcomes of Metastatic Disease to the Sella. Oncologist. ePub, 2019
Harrison RA et al: Intracranial dural, calvarial, and skull base metastases. Handb Clin Neurol. 149:205-25, 2018
Mendez JS et al: Metastatic complications of cancer involving the central and peripheral nervous systems. Neurol Clin. 36(3):579-98, 2018
Bag AK et al: Neuroimaging: intrinsic lesions of the central skull base region. Semin Ultrasound CT MR. 34(5):412-35, 2013
Chamoun RB et al: Management of skull base metastases. Neurosurg Clin N Am. 22(1):61-6, vi-ii, 2011
Mitsuya K et al: Metastatic skull tumors: MRI features and a new conventional classification. J Neurooncol. 104(1):239-45, 2011
Nayak L et al: Intracranial dural metastases. Cancer. 115(9):1947-53, 2009
Pallini R et al: Clivus metastases: report of seven patients and literature review. Acta Neurochir (Wien). 151(4):291-6; discussion 296, 2009
Nemeth AJ et al: Improved detection of skull metastasis with diffusion-weighted MR imaging. AJNR Am J Neuroradiol. 28(6):1088-92, 2007
Quattrocchi CC et al: Bone metastases in breast cancer: higher prevalence of osteosclerotic lesions. Radiol Med. 112(7):1049-59, 2007
Laigle-Donadey F et al: Skull-base metastases. J Neurooncol. 75(1):63-9, 2005
Maroldi R et al: Metastatic disease of the brain: extra-axial metastases (skull, dura, leptomeningeal) and tumour spread. Eur Radiol. 15(3):617-26, 2005
Stark AM et al: Skull metastases: clinical features, differential diagnosis, and review of the literature. Surg Neurol. 60(3):219-25; discussion 225-6, 2003
Gloria-Cruz TI et al: Metastases to temporal bones from primary nonsystemic malignant neoplasms. Arch Otolaryngol Head Neck Surg. 126(2):209-14, 2000
Sze G et al: MR imaging of the cranial meninges with emphasis on contrast enhancement and meningeal carcinomatosis. AJR Am J Roentgenol. 153(5):1039-49, 1989
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