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Gastrointestinal
Diagnosis
Small Intestine
Malignant Neoplasms
Small Bowel Carcinoma
Small Bowel Carcinoma
Atif Zaheer, MD; Michael P. Federle, MD, FACR
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KEY FACTS

  • Terminology

    • Imaging

      • Top Differential Diagnoses

        • Pathology

          • Clinical Issues

            TERMINOLOGY

            • Definitions

              • Primary adenocarcinoma of small intestine (excluding duodenum)
                • Duodenal carcinoma has more in common with gastric cancer
                • Small bowel carcinoma (SBC) has more in common with colon carcinoma

            IMAGING

            • General Features

              • Radiographic Findings

                • CT Findings

                  • MR Findings

                    • Ultrasonographic Findings

                      • Angiographic Findings

                        • Imaging Recommendations

                          DIFFERENTIAL DIAGNOSIS

                            PATHOLOGY

                            • General Features

                              • Gross Pathologic & Surgical Features

                                • Microscopic Features

                                  CLINICAL ISSUES

                                  • Presentation

                                    • Demographics

                                      • Natural History & Prognosis

                                        • Treatment

                                          Selected References

                                          1. Ocasio Quinones GA et al: Small bowel cancer. StatPearls, 2021
                                          2. Vanoli A et al: Prognostic role of mismatch repair status, histotype and high-risk pathologic features in stage II small bowel adenocarcinomas. Ann Surg Oncol.28(2):1167-77, 2020
                                          3. Benson AB et al: Small bowel adenocarcinoma, version 1.2020, NCCN clinical practice guidelines in oncology. J Natl Compr Canc Netw. 17(9):1109-33, 2019
                                          4. Guo XC et al: Retrospective analysis of 119 small bowel adenocarcinoma in Chinese patients. Cancer Invest. 32(5):178-83, 2014
                                          5. Ynson ML et al: What are the latest pharmacotherapy options for small bowel adenocarcinoma? Expert Opin Pharmacother. 15(6):745-8, 2014
                                          6. Chua TC et al: Cytoreductive surgery and perioperative intraperitoneal chemotherapy for peritoneal carcinomatosis from small bowel adenocarcinoma. J Surg Oncol. 100(2):139-43, 2009
                                          7. Tan KY et al: Multimedia articles. Small-bowel tumors with extensive mesenteric involvement can be resected with careful dissection of the mesenteric vessels with good outcomes. Dis Colon Rectum. 52(6):1184-5, 2009
                                          8. Horton KM et al: Multidetector-row computed tomography and 3-dimensional computed tomography imaging of small bowel neoplasms: current concept in diagnosis. J Comput Assist Tomogr. 28(1):106-16, 2004
                                          9. Buckley JA et al: CT evaluation of small bowel neoplasms: spectrum of disease. Radiographics. 18(2):379-92, 1998
                                          10. Laurent F et al: CT of small-bowel neoplasms. Semin Ultrasound CT MR. 16(2):102-11, 1995
                                          Related Anatomy
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                                          Related Differential Diagnoses
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                                          References
                                          Tables

                                          Tables

                                          KEY FACTS

                                          • Terminology

                                            • Imaging

                                              • Top Differential Diagnoses

                                                • Pathology

                                                  • Clinical Issues

                                                    TERMINOLOGY

                                                    • Definitions

                                                      • Primary adenocarcinoma of small intestine (excluding duodenum)
                                                        • Duodenal carcinoma has more in common with gastric cancer
                                                        • Small bowel carcinoma (SBC) has more in common with colon carcinoma

                                                    IMAGING

                                                    • General Features

                                                      • Radiographic Findings

                                                        • CT Findings

                                                          • MR Findings

                                                            • Ultrasonographic Findings

                                                              • Angiographic Findings

                                                                • Imaging Recommendations

                                                                  DIFFERENTIAL DIAGNOSIS

                                                                    PATHOLOGY

                                                                    • General Features

                                                                      • Gross Pathologic & Surgical Features

                                                                        • Microscopic Features

                                                                          CLINICAL ISSUES

                                                                          • Presentation

                                                                            • Demographics

                                                                              • Natural History & Prognosis

                                                                                • Treatment

                                                                                  Selected References

                                                                                  1. Ocasio Quinones GA et al: Small bowel cancer. StatPearls, 2021
                                                                                  2. Vanoli A et al: Prognostic role of mismatch repair status, histotype and high-risk pathologic features in stage II small bowel adenocarcinomas. Ann Surg Oncol.28(2):1167-77, 2020
                                                                                  3. Benson AB et al: Small bowel adenocarcinoma, version 1.2020, NCCN clinical practice guidelines in oncology. J Natl Compr Canc Netw. 17(9):1109-33, 2019
                                                                                  4. Guo XC et al: Retrospective analysis of 119 small bowel adenocarcinoma in Chinese patients. Cancer Invest. 32(5):178-83, 2014
                                                                                  5. Ynson ML et al: What are the latest pharmacotherapy options for small bowel adenocarcinoma? Expert Opin Pharmacother. 15(6):745-8, 2014
                                                                                  6. Chua TC et al: Cytoreductive surgery and perioperative intraperitoneal chemotherapy for peritoneal carcinomatosis from small bowel adenocarcinoma. J Surg Oncol. 100(2):139-43, 2009
                                                                                  7. Tan KY et al: Multimedia articles. Small-bowel tumors with extensive mesenteric involvement can be resected with careful dissection of the mesenteric vessels with good outcomes. Dis Colon Rectum. 52(6):1184-5, 2009
                                                                                  8. Horton KM et al: Multidetector-row computed tomography and 3-dimensional computed tomography imaging of small bowel neoplasms: current concept in diagnosis. J Comput Assist Tomogr. 28(1):106-16, 2004
                                                                                  9. Buckley JA et al: CT evaluation of small bowel neoplasms: spectrum of disease. Radiographics. 18(2):379-92, 1998
                                                                                  10. Laurent F et al: CT of small-bowel neoplasms. Semin Ultrasound CT MR. 16(2):102-11, 1995