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Small Bowel NSAID Stricture
Atif Zaheer, MD; Michael P. Federle, MD, FACR
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KEY FACTS

  • Terminology

    • Imaging

      • Top Differential Diagnoses

        • Pathology

          • Clinical Issues

            TERMINOLOGY

            • Abbreviations

              • Nonsteroidal antiinflammatory drugs (NSAIDs)
            • Synonyms

              • Diaphragm disease
            • Definitions

              • Focal strictures in small bowel (SB) secondary to NSAID use

            IMAGING

            • General Features

              • Fluoroscopic Findings

                • CT Findings

                  • Imaging Recommendations

                    DIFFERENTIAL DIAGNOSIS

                      PATHOLOGY

                      • General Features

                        • Gross Pathologic & Surgical Features

                          • Microscopic Features

                            CLINICAL ISSUES

                            • Presentation

                              • Demographics

                                • Treatment

                                  DIAGNOSTIC CHECKLIST

                                  • Consider

                                    • Image Interpretation Pearls

                                      Selected References

                                      1. Bennett S et al: Diaphragm disease of the terminal ileum presenting as acute small bowel obstruction. BMJ Case Rep. 13(2), 2020
                                      2. Durmush D et al: Small bowel strictures. Curr Opin Gastroenterol. 35(3):235-42, 2019
                                      3. Grattan BJ Jr et al: Diaphragm disease: NSAID-induced small bowel stricture. Case Rep Gastroenterol. 12(2):327-30, 2018
                                      4. Gill RS et al: Small bowel stricture characterization and outcomes of dilatation by double-balloon enteroscopy: a single-centre experience. Therap Adv Gastroenterol. 7(3):108-14, 2014
                                      5. Kishi T et al: CT enteroclysis/enterography findings in drug-induced small-bowel damage. Br J Radiol. 87(1044):20140367, 2014
                                      6. Lim YJ et al: Recent advances in NSAIDs-induced enteropathy therapeutics: new options, new challenges. Gastroenterol Res Pract. 2013:761060, 2013
                                      7. Fortun PJ et al: Nonsteroidal antiinflammatory drugs and the small intestine. Curr Opin Gastroenterol. 21(2):169-75, 2005
                                      8. Scholz FJ et al: Diaphragmlike strictures of the small bowel associated with use of nonsteroidal antiinflammatory drugs. AJR Am J Roentgenol. 162(1):49-50, 1994
                                      Related Anatomy
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                                      Related Differential Diagnoses
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                                      References
                                      Tables

                                      Tables

                                      KEY FACTS

                                      • Terminology

                                        • Imaging

                                          • Top Differential Diagnoses

                                            • Pathology

                                              • Clinical Issues

                                                TERMINOLOGY

                                                • Abbreviations

                                                  • Nonsteroidal antiinflammatory drugs (NSAIDs)
                                                • Synonyms

                                                  • Diaphragm disease
                                                • Definitions

                                                  • Focal strictures in small bowel (SB) secondary to NSAID use

                                                IMAGING

                                                • General Features

                                                  • Fluoroscopic Findings

                                                    • CT Findings

                                                      • Imaging Recommendations

                                                        DIFFERENTIAL DIAGNOSIS

                                                          PATHOLOGY

                                                          • General Features

                                                            • Gross Pathologic & Surgical Features

                                                              • Microscopic Features

                                                                CLINICAL ISSUES

                                                                • Presentation

                                                                  • Demographics

                                                                    • Treatment

                                                                      DIAGNOSTIC CHECKLIST

                                                                      • Consider

                                                                        • Image Interpretation Pearls

                                                                          Selected References

                                                                          1. Bennett S et al: Diaphragm disease of the terminal ileum presenting as acute small bowel obstruction. BMJ Case Rep. 13(2), 2020
                                                                          2. Durmush D et al: Small bowel strictures. Curr Opin Gastroenterol. 35(3):235-42, 2019
                                                                          3. Grattan BJ Jr et al: Diaphragm disease: NSAID-induced small bowel stricture. Case Rep Gastroenterol. 12(2):327-30, 2018
                                                                          4. Gill RS et al: Small bowel stricture characterization and outcomes of dilatation by double-balloon enteroscopy: a single-centre experience. Therap Adv Gastroenterol. 7(3):108-14, 2014
                                                                          5. Kishi T et al: CT enteroclysis/enterography findings in drug-induced small-bowel damage. Br J Radiol. 87(1044):20140367, 2014
                                                                          6. Lim YJ et al: Recent advances in NSAIDs-induced enteropathy therapeutics: new options, new challenges. Gastroenterol Res Pract. 2013:761060, 2013
                                                                          7. Fortun PJ et al: Nonsteroidal antiinflammatory drugs and the small intestine. Curr Opin Gastroenterol. 21(2):169-75, 2005
                                                                          8. Scholz FJ et al: Diaphragmlike strictures of the small bowel associated with use of nonsteroidal antiinflammatory drugs. AJR Am J Roentgenol. 162(1):49-50, 1994