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Smoke Inhalation
John P. Lichtenberger, III, MD; Terrance Healey, MD
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KEY FACTS

  • Terminology

    • Imaging

      • Top Differential Diagnoses

        • Pathology

          • Clinical Issues

            TERMINOLOGY

            • Definitions

              • Inhalation injury to upper and lower respiratory tract from thermal, chemical, and particulate matter (products of combustion)

            IMAGING

            • General Features

              • Radiographic Findings

                • CT Findings

                  • Other Modality Findings

                    • Imaging Recommendations

                      DIFFERENTIAL DIAGNOSIS

                        PATHOLOGY

                        • General Features

                          • Pathophysiology

                            • Gross Pathologic & Surgical Features

                              • Microscopic Features

                                CLINICAL ISSUES

                                • Presentation

                                  • Demographics

                                    • Natural History & Prognosis

                                      • Treatment

                                        DIAGNOSTIC CHECKLIST

                                        • Consider

                                          Selected References

                                          1. Liu X et al: Association of quantitative CT lung density measurements and lung function decline in World Trade Center workers. Clin Respir J. 15(6):613-21, 2020
                                          2. Weber J et al: Quantitative CT evidence of airway inflammation in wtc workers and volunteers with low FVC spirometric pattern. Lung. 198(3):555-63, 2020
                                          3. Björkbom DM et al: Delayed onset pulmonary edema following toxic smoke inhalation; a systematic review. Acute Med. 17(4):203-11, 2018
                                          4. Sabri A et al: The airway in inhalational injury: diagnosis and management. Ann Burns Fire Disasters. 30(1):24-9, 2017
                                          5. Enkhbaatar P et al: Pathophysiology, research challenges, and clinical management of smoke inhalation injury. Lancet. 388(10052):1437-46, 2016
                                          6. Toon MH et al: Management of acute smoke inhalation injury. Crit Care Resusc. 12(1):53-61, 2010
                                          7. Weiden MD et al: Obstructive airways disease with air trapping among firefighters exposed to World Trade Center dust. Chest. 137(3):566-74, 2010
                                          8. Rehberg S et al: Pathophysiology, management and treatment of smoke inhalation injury. Expert Rev Respir Med. 3(3):283-97, 2009
                                          9. Koljonen V et al: Multi-detector computed tomography demonstrates smoke inhalation injury at early stage. Emerg Radiol. 14(2):113-6, 2007
                                          10. Reske A et al: Computed tomography--a possible aid in the diagnosis of smoke inhalation injury? Acta Anaesthesiol Scand. 49(2):257-60, 2005
                                          11. Latenser BA et al: Smoke inhalation injury. Semin Respir Crit Care Med. 22(1):13-22, 2001
                                          12. Teixidor HS et al: Smoke inhalation: radiologic manifestations. Radiology. 149(2):383-7, 1983
                                          Related Anatomy
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                                          Related Differential Diagnoses
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                                          References
                                          Tables

                                          Tables

                                          KEY FACTS

                                          • Terminology

                                            • Imaging

                                              • Top Differential Diagnoses

                                                • Pathology

                                                  • Clinical Issues

                                                    TERMINOLOGY

                                                    • Definitions

                                                      • Inhalation injury to upper and lower respiratory tract from thermal, chemical, and particulate matter (products of combustion)

                                                    IMAGING

                                                    • General Features

                                                      • Radiographic Findings

                                                        • CT Findings

                                                          • Other Modality Findings

                                                            • Imaging Recommendations

                                                              DIFFERENTIAL DIAGNOSIS

                                                                PATHOLOGY

                                                                • General Features

                                                                  • Pathophysiology

                                                                    • Gross Pathologic & Surgical Features

                                                                      • Microscopic Features

                                                                        CLINICAL ISSUES

                                                                        • Presentation

                                                                          • Demographics

                                                                            • Natural History & Prognosis

                                                                              • Treatment

                                                                                DIAGNOSTIC CHECKLIST

                                                                                • Consider

                                                                                  Selected References

                                                                                  1. Liu X et al: Association of quantitative CT lung density measurements and lung function decline in World Trade Center workers. Clin Respir J. 15(6):613-21, 2020
                                                                                  2. Weber J et al: Quantitative CT evidence of airway inflammation in wtc workers and volunteers with low FVC spirometric pattern. Lung. 198(3):555-63, 2020
                                                                                  3. Björkbom DM et al: Delayed onset pulmonary edema following toxic smoke inhalation; a systematic review. Acute Med. 17(4):203-11, 2018
                                                                                  4. Sabri A et al: The airway in inhalational injury: diagnosis and management. Ann Burns Fire Disasters. 30(1):24-9, 2017
                                                                                  5. Enkhbaatar P et al: Pathophysiology, research challenges, and clinical management of smoke inhalation injury. Lancet. 388(10052):1437-46, 2016
                                                                                  6. Toon MH et al: Management of acute smoke inhalation injury. Crit Care Resusc. 12(1):53-61, 2010
                                                                                  7. Weiden MD et al: Obstructive airways disease with air trapping among firefighters exposed to World Trade Center dust. Chest. 137(3):566-74, 2010
                                                                                  8. Rehberg S et al: Pathophysiology, management and treatment of smoke inhalation injury. Expert Rev Respir Med. 3(3):283-97, 2009
                                                                                  9. Koljonen V et al: Multi-detector computed tomography demonstrates smoke inhalation injury at early stage. Emerg Radiol. 14(2):113-6, 2007
                                                                                  10. Reske A et al: Computed tomography--a possible aid in the diagnosis of smoke inhalation injury? Acta Anaesthesiol Scand. 49(2):257-60, 2005
                                                                                  11. Latenser BA et al: Smoke inhalation injury. Semin Respir Crit Care Med. 22(1):13-22, 2001
                                                                                  12. Teixidor HS et al: Smoke inhalation: radiologic manifestations. Radiology. 149(2):383-7, 1983