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Soft Tissue Tumor Mimics: Crystal Disease
Stephanie A. Bernard, MD; Catherine C. Roberts, MD
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KEY FACTS

  • Terminology

    • Top Differential Diagnoses

      • Diagnostic Checklist

        TERMINOLOGY

        • Definitions

          • Group of entities due to crystal deposition that may appear mass-like, mimicking soft tissue tumor

        IMAGING

        • General Features

          • Imaging Recommendations

            DIFFERENTIAL DIAGNOSIS

              DIAGNOSTIC CHECKLIST

              • Image Interpretation Pearls

                Selected References

                1. Hongsmatip P et al: Calcium hydroxyapatite deposition disease: imaging features and presentations mimicking other pathologies. Eur J Radiol. 120:108653, 2019
                2. Kwee RM et al: Calcified or ossified benign soft tissue lesions that may simulate malignancy. Skeletal Radiol. 48(12):1875-90, 2019
                3. Freire V et al: Radiological identification and analysis of soft tissue musculoskeletal calcifications. Insights Imaging. 9(4):477-92, 2018
                4. Yu Z et al: Diagnostic accuracy of dual-energy CT in gout: a systematic review and meta-analysis. Skeletal Radiol. 47(12):1587-93, 2018
                5. Omoumi P et al: Imaging in gout and other crystal-related arthropathies. Rheum Dis Clin North Am. 42(4):621-44, 2016
                6. McKenzie G et al: Pictorial review: non-neoplastic soft-tissue masses. Br J Radiol. 82(981):775-85, 2009
                7. Kransdorf MJ et al: Masses that may mimic soft tissue tumors. In Kransdorf MJ et al: Imaging of Soft Tissue Tumors. 2nd ed. Lippincott Williams & Wilkins. 524-9, 2006
                8. Feydy A et al: Cervical spine and crystal-associated diseases: imaging findings. Eur Radiol. 16(2):459-68, 2006
                9. Olsen KM et al: Tumoral calcinosis: pearls, polemics, and alternative possibilities. Radiographics. 26(3):871-85, 2006
                10. Flemming DJ et al: Osseous involvement in calcific tendinitis: a retrospective review of 50 cases. AJR Am J Roentgenol. 181(4):965-72, 2003
                11. Jelinek J et al: MR imaging of soft-tissue masses. Mass-like lesions that simulate neoplasms. Magn Reson Imaging Clin N Am. 3(4):727-41, 1995
                Related Anatomy
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                Related Differential Diagnoses
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                References
                Tables

                Tables

                KEY FACTS

                • Terminology

                  • Top Differential Diagnoses

                    • Diagnostic Checklist

                      TERMINOLOGY

                      • Definitions

                        • Group of entities due to crystal deposition that may appear mass-like, mimicking soft tissue tumor

                      IMAGING

                      • General Features

                        • Imaging Recommendations

                          DIFFERENTIAL DIAGNOSIS

                            DIAGNOSTIC CHECKLIST

                            • Image Interpretation Pearls

                              Selected References

                              1. Hongsmatip P et al: Calcium hydroxyapatite deposition disease: imaging features and presentations mimicking other pathologies. Eur J Radiol. 120:108653, 2019
                              2. Kwee RM et al: Calcified or ossified benign soft tissue lesions that may simulate malignancy. Skeletal Radiol. 48(12):1875-90, 2019
                              3. Freire V et al: Radiological identification and analysis of soft tissue musculoskeletal calcifications. Insights Imaging. 9(4):477-92, 2018
                              4. Yu Z et al: Diagnostic accuracy of dual-energy CT in gout: a systematic review and meta-analysis. Skeletal Radiol. 47(12):1587-93, 2018
                              5. Omoumi P et al: Imaging in gout and other crystal-related arthropathies. Rheum Dis Clin North Am. 42(4):621-44, 2016
                              6. McKenzie G et al: Pictorial review: non-neoplastic soft-tissue masses. Br J Radiol. 82(981):775-85, 2009
                              7. Kransdorf MJ et al: Masses that may mimic soft tissue tumors. In Kransdorf MJ et al: Imaging of Soft Tissue Tumors. 2nd ed. Lippincott Williams & Wilkins. 524-9, 2006
                              8. Feydy A et al: Cervical spine and crystal-associated diseases: imaging findings. Eur Radiol. 16(2):459-68, 2006
                              9. Olsen KM et al: Tumoral calcinosis: pearls, polemics, and alternative possibilities. Radiographics. 26(3):871-85, 2006
                              10. Flemming DJ et al: Osseous involvement in calcific tendinitis: a retrospective review of 50 cases. AJR Am J Roentgenol. 181(4):965-72, 2003
                              11. Jelinek J et al: MR imaging of soft-tissue masses. Mass-like lesions that simulate neoplasms. Magn Reson Imaging Clin N Am. 3(4):727-41, 1995