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Solid Pleural Metastases
Melissa L. Rosado-de-Christenson, MD, FACR, FAAWR
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KEY FACTS

  • Terminology

    • Imaging

      • Top Differential Diagnoses

        • Pathology

          • Clinical Issues

            • Diagnostic Checklist

              TERMINOLOGY

              • Definitions

                • Secondary pleural malignancy; thickening, nodules, masses
                • Most common etiology of malignant pleural thickening

              IMAGING

              • General Features

                • Radiographic Findings

                  • CT Findings

                    • MR Findings

                      • Nuclear Medicine Findings

                        • Imaging Recommendations

                          DIFFERENTIAL DIAGNOSIS

                            PATHOLOGY

                            • General Features

                              • Staging, Grading, & Classification

                                • Gross Pathologic & Surgical Features

                                  • Microscopic Features

                                    CLINICAL ISSUES

                                    • Presentation

                                      • Natural History & Prognosis

                                        • Treatment

                                          DIAGNOSTIC CHECKLIST

                                          • Consider

                                            • Image Interpretation Pearls

                                              Selected References

                                              1. Ribeiro AMB et al: Diffuse pleural metastases of osteosarcoma detected by bone scan. World J Nucl Med. 19(3):310-2, 2020
                                              2. Skok K et al: Malignant pleural effusion and its current management: a review. Medicina (Kaunas). 55(8), 2019
                                              3. Riihimäki M et al: Clinical landscape of cancer metastases. Cancer Med. 7(11):5534-42, 2018
                                              4. Hallifax RJ et al: State-of-the-art: radiological investigation of pleural disease. Respir Med. 124:88-99, 2017
                                              5. Puchalski J: Pulmonary manifestations of solid non-pulmonary malignancies. Clin Chest Med. 38(2):177-86, 2017
                                              6. Shroff GS et al: Imaging of metastases in the chest: mechanisms of spread and potential pitfalls. Semin Ultrasound CT MR. 38(6):594-603, 2017
                                              7. Hayes SA et al: Imaging of thoracic cavity tumors. Surg Oncol Clin N Am. 23(4):709-33, 2014
                                              8. Martínez-Jiménez S et al: Imaging features of thoracic metastases from gynecologic neoplasms. Radiographics. 34(6):1742-54, 2014
                                              9. Kruse M et al: FDG PET/CT in the management of primary pleural tumors and pleural metastases. AJR Am J Roentgenol. 201(2):W215-26, 2013
                                              10. Qureshi NR et al: Imaging of pleural disease. Clin Chest Med. 27(2):193-213, 2006
                                              11. Rosado-de-Christenson ML et al: From the archives of the AFIP: Localized fibrous tumor of the pleura. Radiographics. 23(3):759-83, 2003
                                              12. Hierholzer J et al: MRI and CT in the differential diagnosis of pleural disease. Chest. 118(3):604-9, 2000
                                              13. Leung AN et al: CT in differential diagnosis of diffuse pleural disease. AJR Am J Roentgenol. 154(3):487-92, 1990
                                              Related Anatomy
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                                              Related Differential Diagnoses
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                                              References
                                              Tables

                                              Tables

                                              KEY FACTS

                                              • Terminology

                                                • Imaging

                                                  • Top Differential Diagnoses

                                                    • Pathology

                                                      • Clinical Issues

                                                        • Diagnostic Checklist

                                                          TERMINOLOGY

                                                          • Definitions

                                                            • Secondary pleural malignancy; thickening, nodules, masses
                                                            • Most common etiology of malignant pleural thickening

                                                          IMAGING

                                                          • General Features

                                                            • Radiographic Findings

                                                              • CT Findings

                                                                • MR Findings

                                                                  • Nuclear Medicine Findings

                                                                    • Imaging Recommendations

                                                                      DIFFERENTIAL DIAGNOSIS

                                                                        PATHOLOGY

                                                                        • General Features

                                                                          • Staging, Grading, & Classification

                                                                            • Gross Pathologic & Surgical Features

                                                                              • Microscopic Features

                                                                                CLINICAL ISSUES

                                                                                • Presentation

                                                                                  • Natural History & Prognosis

                                                                                    • Treatment

                                                                                      DIAGNOSTIC CHECKLIST

                                                                                      • Consider

                                                                                        • Image Interpretation Pearls

                                                                                          Selected References

                                                                                          1. Ribeiro AMB et al: Diffuse pleural metastases of osteosarcoma detected by bone scan. World J Nucl Med. 19(3):310-2, 2020
                                                                                          2. Skok K et al: Malignant pleural effusion and its current management: a review. Medicina (Kaunas). 55(8), 2019
                                                                                          3. Riihimäki M et al: Clinical landscape of cancer metastases. Cancer Med. 7(11):5534-42, 2018
                                                                                          4. Hallifax RJ et al: State-of-the-art: radiological investigation of pleural disease. Respir Med. 124:88-99, 2017
                                                                                          5. Puchalski J: Pulmonary manifestations of solid non-pulmonary malignancies. Clin Chest Med. 38(2):177-86, 2017
                                                                                          6. Shroff GS et al: Imaging of metastases in the chest: mechanisms of spread and potential pitfalls. Semin Ultrasound CT MR. 38(6):594-603, 2017
                                                                                          7. Hayes SA et al: Imaging of thoracic cavity tumors. Surg Oncol Clin N Am. 23(4):709-33, 2014
                                                                                          8. Martínez-Jiménez S et al: Imaging features of thoracic metastases from gynecologic neoplasms. Radiographics. 34(6):1742-54, 2014
                                                                                          9. Kruse M et al: FDG PET/CT in the management of primary pleural tumors and pleural metastases. AJR Am J Roentgenol. 201(2):W215-26, 2013
                                                                                          10. Qureshi NR et al: Imaging of pleural disease. Clin Chest Med. 27(2):193-213, 2006
                                                                                          11. Rosado-de-Christenson ML et al: From the archives of the AFIP: Localized fibrous tumor of the pleura. Radiographics. 23(3):759-83, 2003
                                                                                          12. Hierholzer J et al: MRI and CT in the differential diagnosis of pleural disease. Chest. 118(3):604-9, 2000
                                                                                          13. Leung AN et al: CT in differential diagnosis of diffuse pleural disease. AJR Am J Roentgenol. 154(3):487-92, 1990