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Solid Pseudopapillary Neoplasm
Alexander J. Towbin, MD
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KEY FACTS

  • Terminology

    • Imaging

      • Top Differential Diagnoses

        • Clinical Issues

          TERMINOLOGY

          • Synonyms

            • Solid-cystic pancreatic tumor, Frantz tumor, papillary cystic tumor, solid & papillary neoplasm, solid & cystic acinar cell tumor, papillary epithelial neoplasm
          • Definitions

            • Exocrine tumor of pancreas

          IMAGING

          • General Features

            • Radiographic Findings

              • Ultrasonographic Findings

                • CT Findings

                  • MR Findings

                    • Nuclear Medicine Findings

                      • Imaging Recommendations

                        DIFFERENTIAL DIAGNOSIS

                          PATHOLOGY

                          • Gross Pathologic & Surgical Features

                            CLINICAL ISSUES

                            • Presentation

                              • Demographics

                                • Natural History & Prognosis

                                  • Treatment

                                    DIAGNOSTIC CHECKLIST

                                    • Consider

                                      Selected References

                                      1. Qiu L et al: Pancreatic masses in children and young adults: multimodality review with pathologic correlation. Radiographics. 41(6):1766-84, 2021
                                      2. Yang Z et al: Differential diagnosis of pancreatoblastoma (PB) and solid pseudopapillary neoplasms (SPNs) in children by CT and MR imaging. Eur Radiol. 31(4):2209-17, 2020
                                      3. Waters AM et al: Comparison of pediatric and adult solid pseudopapillary neoplasms of the pancreas. J Surg Res. 242:312-7, 2019
                                      4. Xu M et al: Application of contrast-enhanced ultrasound in the diagnosis of solid pseudopapillary tumors of the pancreas: imaging findings compared with contrast-enhanced computed tomography. J Ultrasound Med. 38(12):3247-55, 2019
                                      5. Mylonas KS et al: Solid pseudopapillary and malignant pancreatic tumors in childhood: a systematic review and evidence quality assessment. Pediatr Blood Cancer. 65(10):e27114, 2018
                                      6. Anil G et al: Solid pseudopapillary neoplasm of the pancreas: CT imaging features and radiologic-pathologic correlation. Diagn Interv Radiol. 23(2):94-9, 2017
                                      7. Dai G et al: Solid pseudopapillary neoplasms of the pancreas: clinical analysis of 45 cases. Int J Clin Exp Pathol. 8(9):11400-6, 2015
                                      8. Kang CM et al: Clinical correlations with (18)FDG PET scan patterns in solid pseudopapillary tumors of the pancreas: still a surgical enigma? Pancreatology. 14(6):515-23, 2014
                                      9. Ventriglia A et al: MRI features of solid pseudopapillary neoplasm of the pancreas. Abdom Imaging. 39(6):1213-20, 2014
                                      Related Anatomy
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                                      Related Differential Diagnoses
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                                      References
                                      Tables

                                      Tables

                                      KEY FACTS

                                      • Terminology

                                        • Imaging

                                          • Top Differential Diagnoses

                                            • Clinical Issues

                                              TERMINOLOGY

                                              • Synonyms

                                                • Solid-cystic pancreatic tumor, Frantz tumor, papillary cystic tumor, solid & papillary neoplasm, solid & cystic acinar cell tumor, papillary epithelial neoplasm
                                              • Definitions

                                                • Exocrine tumor of pancreas

                                              IMAGING

                                              • General Features

                                                • Radiographic Findings

                                                  • Ultrasonographic Findings

                                                    • CT Findings

                                                      • MR Findings

                                                        • Nuclear Medicine Findings

                                                          • Imaging Recommendations

                                                            DIFFERENTIAL DIAGNOSIS

                                                              PATHOLOGY

                                                              • Gross Pathologic & Surgical Features

                                                                CLINICAL ISSUES

                                                                • Presentation

                                                                  • Demographics

                                                                    • Natural History & Prognosis

                                                                      • Treatment

                                                                        DIAGNOSTIC CHECKLIST

                                                                        • Consider

                                                                          Selected References

                                                                          1. Qiu L et al: Pancreatic masses in children and young adults: multimodality review with pathologic correlation. Radiographics. 41(6):1766-84, 2021
                                                                          2. Yang Z et al: Differential diagnosis of pancreatoblastoma (PB) and solid pseudopapillary neoplasms (SPNs) in children by CT and MR imaging. Eur Radiol. 31(4):2209-17, 2020
                                                                          3. Waters AM et al: Comparison of pediatric and adult solid pseudopapillary neoplasms of the pancreas. J Surg Res. 242:312-7, 2019
                                                                          4. Xu M et al: Application of contrast-enhanced ultrasound in the diagnosis of solid pseudopapillary tumors of the pancreas: imaging findings compared with contrast-enhanced computed tomography. J Ultrasound Med. 38(12):3247-55, 2019
                                                                          5. Mylonas KS et al: Solid pseudopapillary and malignant pancreatic tumors in childhood: a systematic review and evidence quality assessment. Pediatr Blood Cancer. 65(10):e27114, 2018
                                                                          6. Anil G et al: Solid pseudopapillary neoplasm of the pancreas: CT imaging features and radiologic-pathologic correlation. Diagn Interv Radiol. 23(2):94-9, 2017
                                                                          7. Dai G et al: Solid pseudopapillary neoplasms of the pancreas: clinical analysis of 45 cases. Int J Clin Exp Pathol. 8(9):11400-6, 2015
                                                                          8. Kang CM et al: Clinical correlations with (18)FDG PET scan patterns in solid pseudopapillary tumors of the pancreas: still a surgical enigma? Pancreatology. 14(6):515-23, 2014
                                                                          9. Ventriglia A et al: MRI features of solid pseudopapillary neoplasm of the pancreas. Abdom Imaging. 39(6):1213-20, 2014