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Solid Pseudopapillary Neoplasm
Tara A. Morgan, MD
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KEY FACTS

  • Terminology

    • Imaging

      • Top Differential Diagnoses

        • Pathology

          • Clinical Issues

            • Diagnostic Checklist

              TERMINOLOGY

              • Synonyms

                • Solid and papillary epithelial neoplasm (SPEN); papillary cystic epithelial neoplasm; papillary cystic tumor; solid and cystic tumor of pancreas, Franz or Hamoudi tumor
              • Definitions

                • Epithelial tumor of exocrine pancreas with low-grade malignant potential and solid and cystic features

              IMAGING

              • General Features

                • Ultrasonographic Findings

                  • CT Findings

                    • MR Findings

                      • Imaging Recommendations

                        DIFFERENTIAL DIAGNOSIS

                          PATHOLOGY

                          • General Features

                            • Gross Pathologic & Surgical Features

                              • Microscopic Features

                                CLINICAL ISSUES

                                • Presentation

                                  • Demographics

                                    • Natural History & Prognosis

                                      • Treatment

                                        DIAGNOSTIC CHECKLIST

                                        • Image Interpretation Pearls

                                          Selected References

                                          1. Hansen CP et al: Solid pseudopapillary neoplasm of the pancreas: clinical-pathological features and management, a single-center experience. Rare Tumors. 11:2036361319878513, 2019
                                          2. Xu M et al: Application of contrast-enhanced ultrasound in the diagnosis of solid pseudopapillary tumors of the pancreas: imaging findings compared with contrast-enhanced computed tomography. J Ultrasound Med. 38(12):3247-55, 2019
                                          3. Jiang L et al: Solid pseudopapillary tumors of the pancreas: findings from routine screening sonographic examination and the value of contrast-enhanced ultrasound. J Clin Ultrasound. 43(5):277-82, 2015
                                          4. Ganeshan DM et al: Solid pseudo-papillary tumors of the pancreas: current update. Abdom Imaging. 38(6):1373-82, 2013
                                          5. Yu MH et al: MR imaging features of small solid pseudopapillary tumors: retrospective differentiation from other small solid pancreatic tumors. AJR Am J Roentgenol. 195(6):1324-32, 2010
                                          6. Reddy S et al: Surgical management of solid-pseudopapillary neoplasms of the pancreas (Franz or Hamoudi tumors): a large single-institutional series. J Am Coll Surg. 208(5):950-7; discussion 957-9, 2009
                                          7. Wang DB et al: Imaging features of solid pseudopapillary tumor of the pancreas on multi-detector row computed tomography. World J Gastroenterol. 15(7):829-35, 2009
                                          8. Choi JY et al: Solid pseudopapillary tumor of the pancreas: typical and atypical manifestations. AJR Am J Roentgenol. 187(2):W178-86, 2006
                                          9. Papavramidis T et al: Solid pseudopapillary tumors of the pancreas: review of 718 patients reported in English literature. J Am Coll Surg. 200(6):965-72, 2005
                                          Related Anatomy
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                                          Related Differential Diagnoses
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                                          References
                                          Tables

                                          Tables

                                          KEY FACTS

                                          • Terminology

                                            • Imaging

                                              • Top Differential Diagnoses

                                                • Pathology

                                                  • Clinical Issues

                                                    • Diagnostic Checklist

                                                      TERMINOLOGY

                                                      • Synonyms

                                                        • Solid and papillary epithelial neoplasm (SPEN); papillary cystic epithelial neoplasm; papillary cystic tumor; solid and cystic tumor of pancreas, Franz or Hamoudi tumor
                                                      • Definitions

                                                        • Epithelial tumor of exocrine pancreas with low-grade malignant potential and solid and cystic features

                                                      IMAGING

                                                      • General Features

                                                        • Ultrasonographic Findings

                                                          • CT Findings

                                                            • MR Findings

                                                              • Imaging Recommendations

                                                                DIFFERENTIAL DIAGNOSIS

                                                                  PATHOLOGY

                                                                  • General Features

                                                                    • Gross Pathologic & Surgical Features

                                                                      • Microscopic Features

                                                                        CLINICAL ISSUES

                                                                        • Presentation

                                                                          • Demographics

                                                                            • Natural History & Prognosis

                                                                              • Treatment

                                                                                DIAGNOSTIC CHECKLIST

                                                                                • Image Interpretation Pearls

                                                                                  Selected References

                                                                                  1. Hansen CP et al: Solid pseudopapillary neoplasm of the pancreas: clinical-pathological features and management, a single-center experience. Rare Tumors. 11:2036361319878513, 2019
                                                                                  2. Xu M et al: Application of contrast-enhanced ultrasound in the diagnosis of solid pseudopapillary tumors of the pancreas: imaging findings compared with contrast-enhanced computed tomography. J Ultrasound Med. 38(12):3247-55, 2019
                                                                                  3. Jiang L et al: Solid pseudopapillary tumors of the pancreas: findings from routine screening sonographic examination and the value of contrast-enhanced ultrasound. J Clin Ultrasound. 43(5):277-82, 2015
                                                                                  4. Ganeshan DM et al: Solid pseudo-papillary tumors of the pancreas: current update. Abdom Imaging. 38(6):1373-82, 2013
                                                                                  5. Yu MH et al: MR imaging features of small solid pseudopapillary tumors: retrospective differentiation from other small solid pancreatic tumors. AJR Am J Roentgenol. 195(6):1324-32, 2010
                                                                                  6. Reddy S et al: Surgical management of solid-pseudopapillary neoplasms of the pancreas (Franz or Hamoudi tumors): a large single-institutional series. J Am Coll Surg. 208(5):950-7; discussion 957-9, 2009
                                                                                  7. Wang DB et al: Imaging features of solid pseudopapillary tumor of the pancreas on multi-detector row computed tomography. World J Gastroenterol. 15(7):829-35, 2009
                                                                                  8. Choi JY et al: Solid pseudopapillary tumor of the pancreas: typical and atypical manifestations. AJR Am J Roentgenol. 187(2):W178-86, 2006
                                                                                  9. Papavramidis T et al: Solid pseudopapillary tumors of the pancreas: review of 718 patients reported in English literature. J Am Coll Surg. 200(6):965-72, 2005