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Solitary Fibrous Tumor and Hemangiopericytoma
Catherine C. Roberts, MD; B.J. Manaster, MD, PhD, FACR
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KEY FACTS

  • Terminology

    • Imaging

      • Clinical Issues

        TERMINOLOGY

        • Abbreviations

          • Solitary fibrous tumor (SFT)
          • Hemangiopericytoma (HPC)
        • Definitions

          • Solitary fibrous tumor
            • Mesenchymal tumor, likely fibroblastic type, with hemangiopericytoma-like branching vessels
          • Hemangiopericytoma
            • Formerly used to describe wide variety of neoplasms with thin-walled branching vessels
              • Most were histologically similar to solitary fibrous tumor and may represent same lesion
            • Also refers to distinct entity arising from pericytes
          • Solitary fibrous tumor and hemangiopericytoma are currently used almost interchangeably

        IMAGING

        • General Features

          • Imaging Recommendations

            • Radiographic Findings

              • CT Findings

                • MR Findings

                  • Ultrasonographic Findings

                    DIFFERENTIAL DIAGNOSIS

                      PATHOLOGY

                      • General Features

                        • Staging, Grading, & Classification

                          • Gross Pathologic & Surgical Features

                            • Microscopic Features

                              CLINICAL ISSUES

                              • Presentation

                                • Demographics

                                  • Natural History & Prognosis

                                    • Treatment

                                      Selected References

                                      1. Frazier AA: The Yin and Yang of solitary fibrous tumor. Radiographics. 34(2):294, 2014
                                      2. Garcia-Bennett J et al: Soft tissue solitary fibrous tumor. Imaging findings in a series of nine cases. Skeletal Radiol. 41(11):1427-33, 2012
                                      3. Musyoki FN et al: Solitary fibrous tumor: an update on the spectrum of extrapleural manifestations. Skeletal Radiol. 41(1):5-13, 2012
                                      4. Shanbhogue AK et al: Somatic and visceral solitary fibrous tumors in the abdomen and pelvis: cross-sectional imaging spectrum. Radiographics. 31(2):393-408, 2011
                                      5. Aftab S et al: Fat-forming solitary fibrous tumour (lipomatous haemangiopericytoma) of the spine: case report and literature review. Skeletal Radiol. 39(10):1039-42, 2010
                                      6. Wignall OJ et al: Solitary fibrous tumors of the soft tissues: review of the imaging and clinical features with histopathologic correlation. AJR Am J Roentgenol. 195(1):W55-62, 2010
                                      7. Park MS et al: New insights into the hemangiopericytoma/solitary fibrous tumor spectrum of tumors. Curr Opin Oncol. 21(4):327-31, 2009
                                      8. Kim HJ et al: Solitary fibrous tumor of the orbit: CT and MR imaging findings. AJNR Am J Neuroradiol. 29(5):857-62, 2008
                                      9. Weiss SW et al: Soft tissue tumors of intermediate malignancy of uncertain type. In Weiss SW et al: Enzinger and Weiss' Soft Tissue Tumors. 5th ed. Philadelphia: Elsevier. 1120-35, 2008
                                      10. Kransdorf MJ et al: Vascular and lymphatic tumors. In Kransdorf MJ et al: Imaging of Soft Tissue Tumors. 2nd ed. Philadelphia: Lippincott Williams & Wilkins. 179, 2006
                                      11. Levy AD et al: From the archives of the AFIP: benign fibrous tumors and tumorlike lesions of the mesentery: radiologic-pathologic correlation. Radiographics. 26(1):245-64, 2006
                                      12. Guillou L et al: Extrapleural solitary fibrous tumor and hemangiopericytoma. In Fletcher CDM et al: World Health Organization Classification of Tumours. Pathology and Genetics of Tumours of Soft Tissue and Bone. Lyon: IARC Press. 86-90, 2002
                                      Related Anatomy
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                                      Related Differential Diagnoses
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                                      References
                                      Tables

                                      Tables

                                      KEY FACTS

                                      • Terminology

                                        • Imaging

                                          • Clinical Issues

                                            TERMINOLOGY

                                            • Abbreviations

                                              • Solitary fibrous tumor (SFT)
                                              • Hemangiopericytoma (HPC)
                                            • Definitions

                                              • Solitary fibrous tumor
                                                • Mesenchymal tumor, likely fibroblastic type, with hemangiopericytoma-like branching vessels
                                              • Hemangiopericytoma
                                                • Formerly used to describe wide variety of neoplasms with thin-walled branching vessels
                                                  • Most were histologically similar to solitary fibrous tumor and may represent same lesion
                                                • Also refers to distinct entity arising from pericytes
                                              • Solitary fibrous tumor and hemangiopericytoma are currently used almost interchangeably

                                            IMAGING

                                            • General Features

                                              • Imaging Recommendations

                                                • Radiographic Findings

                                                  • CT Findings

                                                    • MR Findings

                                                      • Ultrasonographic Findings

                                                        DIFFERENTIAL DIAGNOSIS

                                                          PATHOLOGY

                                                          • General Features

                                                            • Staging, Grading, & Classification

                                                              • Gross Pathologic & Surgical Features

                                                                • Microscopic Features

                                                                  CLINICAL ISSUES

                                                                  • Presentation

                                                                    • Demographics

                                                                      • Natural History & Prognosis

                                                                        • Treatment

                                                                          Selected References

                                                                          1. Frazier AA: The Yin and Yang of solitary fibrous tumor. Radiographics. 34(2):294, 2014
                                                                          2. Garcia-Bennett J et al: Soft tissue solitary fibrous tumor. Imaging findings in a series of nine cases. Skeletal Radiol. 41(11):1427-33, 2012
                                                                          3. Musyoki FN et al: Solitary fibrous tumor: an update on the spectrum of extrapleural manifestations. Skeletal Radiol. 41(1):5-13, 2012
                                                                          4. Shanbhogue AK et al: Somatic and visceral solitary fibrous tumors in the abdomen and pelvis: cross-sectional imaging spectrum. Radiographics. 31(2):393-408, 2011
                                                                          5. Aftab S et al: Fat-forming solitary fibrous tumour (lipomatous haemangiopericytoma) of the spine: case report and literature review. Skeletal Radiol. 39(10):1039-42, 2010
                                                                          6. Wignall OJ et al: Solitary fibrous tumors of the soft tissues: review of the imaging and clinical features with histopathologic correlation. AJR Am J Roentgenol. 195(1):W55-62, 2010
                                                                          7. Park MS et al: New insights into the hemangiopericytoma/solitary fibrous tumor spectrum of tumors. Curr Opin Oncol. 21(4):327-31, 2009
                                                                          8. Kim HJ et al: Solitary fibrous tumor of the orbit: CT and MR imaging findings. AJNR Am J Neuroradiol. 29(5):857-62, 2008
                                                                          9. Weiss SW et al: Soft tissue tumors of intermediate malignancy of uncertain type. In Weiss SW et al: Enzinger and Weiss' Soft Tissue Tumors. 5th ed. Philadelphia: Elsevier. 1120-35, 2008
                                                                          10. Kransdorf MJ et al: Vascular and lymphatic tumors. In Kransdorf MJ et al: Imaging of Soft Tissue Tumors. 2nd ed. Philadelphia: Lippincott Williams & Wilkins. 179, 2006
                                                                          11. Levy AD et al: From the archives of the AFIP: benign fibrous tumors and tumorlike lesions of the mesentery: radiologic-pathologic correlation. Radiographics. 26(1):245-64, 2006
                                                                          12. Guillou L et al: Extrapleural solitary fibrous tumor and hemangiopericytoma. In Fletcher CDM et al: World Health Organization Classification of Tumours. Pathology and Genetics of Tumours of Soft Tissue and Bone. Lyon: IARC Press. 86-90, 2002