Mesenchymal neoplasm composed of oval to spindle-shaped cells with prominent branching (HPC-like) vascular pattern
Bone
Most previously diagnosed HPCs of bone are now classified as SFTs
CNS
SFT/HPC terminology still utilized
Considered to exist in spectrum
Tumors previously considered SFTs represent lower end of spectrum with more indolent behavior
Tumors previously considered HPCs in CNS represent higher end of spectrum with less favorable prognosis
Most SFTs/HPCs harbor NAB2/STAT6 fusion
IMAGING
General Features
Radiographic Findings
CT Findings
MR Findings
Angiographic Findings
Nonvascular Interventions
Nuclear Medicine Findings
Imaging Recommendations
DIFFERENTIAL DIAGNOSIS
PATHOLOGY
General Features
Gross Pathologic & Surgical Features
Microscopic Features
CLINICAL ISSUES
Presentation
Demographics
Natural History & Prognosis
Treatment
DIAGNOSTIC CHECKLIST
Consider
Selected References
González-Vargas PM et al: Hemangiopericytoma/solitary fibrous tumor in the central nervous system. Experience with surgery and radiotherapy as a complementary treatment: a 10-year analysis of a heterogeneous series in a single tertiary center. Neurocirugia (Astur). 31(1):14-23, 2020
Koeller KK et al: Intradural extramedullary spinal neoplasms: radiologic-pathologic correlation. radiographics. 39(2):468-90, 2019
Li Z et al: Primary epidural hemangiopericytoma of the thoracic spine: case report and literature review. J Clin Neurosci. 60:142-7, 2019
Chen H et al: Solitary fibrous tumor of the central nervous system: a clinicopathologic study of 24 cases. Acta Neurochir (Wien). 154(2):237-48, 2012
Verbeke SL et al: A reappraisal of hemangiopericytoma of bone; analysis of cases reclassified as synovial sarcoma and solitary fibrous tumor of bone. Am J Surg Pathol. 34(6):777-83, 2010
Fitzpatrick D et al: Intradural hemangiopericytoma of the lumbar spine: a rare entity. AJNR Am J Neuroradiol. 30(1):152-4, 2009
Park MS et al: New insights into the hemangiopericytoma/solitary fibrous tumor spectrum of tumors. Curr Opin Oncol. 21(4):327-31, 2009
Kashiwazaki D et al: Subpial hemangiopericytoma with marked extramedullary growth: case report. Neurosurgery. 61(6):E1336-7; discussion E1337, 2007
Gengler C et al: Solitary fibrous tumour and haemangiopericytoma: evolution of a concept. Histopathology. 48(1):63-74, 2006
Cox DP et al: Myopericytoma of the thoracic spine: a case report. Spine. 28(2):E30-2, 2003
Musacchio M et al: Posterior cervical haemangiopericytoma with intracranial and skull base extension. Diagnostic and therapeutic challenge of a rare hypervascular neoplasm. J Neuroradiol. 30(3):180-7, 2003
Woitzik J et al: Delayed manifestation of spinal metastasis: a special feature of hemangiopericytoma. Clin Neurol Neurosurg. 105(3):159-66, 2003
Akhaddar A et al: Thoracic epidural hemangiopericytoma. Case report. J Neurosurg Sci. 46(2):89-92; discussion 92, 2002
Betchen S et al: Intradural hemangiopericytoma of the lumbar spine: case report. Neurosurgery. 50(3):654-7, 2002
Ijiri K et al: Primary epidural hemangiopericytoma in the lumbar spine: a case report. Spine (Phila Pa 1976). 27(7):E189-92, 2002
Tayoro K et al: [Imaging of meningeal hemangiopericytomas] J Radiol. 83(4 Pt 1):459-65, 2002
Suzuki SO et al: Clinicopathological features of solitary fibrous tumor of the meninges: An immunohistochemical reappraisal of cases previously diagnosed to be fibrous meningioma or hemangiopericytoma. Pathol Int. 50(10):808-17, 2000
Nonaka M et al: Metastatic meningeal hemangiopericytoma of thoracic spine. Clin Neurol Neurosurg. 100(3):228-30, 1998
Lin YJ et al: Primary hemangiopericytoma in the axis bone: case report and review of literature. Neurosurgery. 39(2):397-9; discussion 399-400, 1996
Murphey MD et al: From the archives of the AFIP. Musculoskeletal angiomatous lesions: radiologic-pathologic correlation. Radiographics. 15(4):893-917, 1995
Kozlowski K et al: Primary sacral bone tumours in children (report of 16 cases with a short literature review). Australas Radiol. 34(2):142-9, 1990
Bridges LR et al: Haemangiopericytic meningioma of the sacral canal: a case report. J Neurol Neurosurg Psychiatry. 51(2):288-90, 1988
Cuccurullo L et al: Hemangiopericytoma of the cervical spine. A case report. Acta Neurol (Napoli). 6(6):472-81, 1984
Beadle GF et al: Treatment of advanced malignant hemangiopericytoma with combination adriamycin and DTIC: a report of four cases. J Surg Oncol. 22(3):167-70, 1983
Muraszko KM et al: Hemangiopericytomas of the spine. Neurosurgery. 10(4):473-9, 1982
Cappabianca P et al: Hemangiopericytoma of the spinal canal. Surg Neurol. 15(4):298-302, 1981
Anderson C et al: Skeletal metastases of an intracranial malignant hemangiopericytoma. Report of a case. J Bone Joint Surg Am. 62(1):145-8, 1980
Stern MB et al: Hemangiopericytoma of the cervical spine: report of an unusual case. Clin Orthop. (151):201-4, 1980
Subbarao K et al: Primary malignant neoplasms. Semin Roentgenol. 14(1):44-57, 1979
Harris DJ et al: Hemangiopericytoma of the spinal canal. Report of three cases. J Neurosurg. 49(6):914-20, 1978
Hart S et al: Haemangiopericytoma of the pre-sacral space. Br J Surg. 60(7):583-4, 1973
Baxter PJ et al: Haemangiopericytoma. Light and electron microscopy studies of a cerebral secondary tumour. Acta Neuropathol (Berl). 21(3):253-7, 1972
Related Anatomy
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References
Tables
Tables
KEY FACTS
Terminology
Imaging
Top Differential Diagnoses
Pathology
Clinical Issues
TERMINOLOGY
Abbreviations
Solitary fibrous tumor (SFT)
Hemangiopericytoma (HPC)
Definitions
Mesenchymal neoplasm composed of oval to spindle-shaped cells with prominent branching (HPC-like) vascular pattern
Bone
Most previously diagnosed HPCs of bone are now classified as SFTs
CNS
SFT/HPC terminology still utilized
Considered to exist in spectrum
Tumors previously considered SFTs represent lower end of spectrum with more indolent behavior
Tumors previously considered HPCs in CNS represent higher end of spectrum with less favorable prognosis
Most SFTs/HPCs harbor NAB2/STAT6 fusion
IMAGING
General Features
Radiographic Findings
CT Findings
MR Findings
Angiographic Findings
Nonvascular Interventions
Nuclear Medicine Findings
Imaging Recommendations
DIFFERENTIAL DIAGNOSIS
PATHOLOGY
General Features
Gross Pathologic & Surgical Features
Microscopic Features
CLINICAL ISSUES
Presentation
Demographics
Natural History & Prognosis
Treatment
DIAGNOSTIC CHECKLIST
Consider
Selected References
González-Vargas PM et al: Hemangiopericytoma/solitary fibrous tumor in the central nervous system. Experience with surgery and radiotherapy as a complementary treatment: a 10-year analysis of a heterogeneous series in a single tertiary center. Neurocirugia (Astur). 31(1):14-23, 2020
Koeller KK et al: Intradural extramedullary spinal neoplasms: radiologic-pathologic correlation. radiographics. 39(2):468-90, 2019
Li Z et al: Primary epidural hemangiopericytoma of the thoracic spine: case report and literature review. J Clin Neurosci. 60:142-7, 2019
Chen H et al: Solitary fibrous tumor of the central nervous system: a clinicopathologic study of 24 cases. Acta Neurochir (Wien). 154(2):237-48, 2012
Verbeke SL et al: A reappraisal of hemangiopericytoma of bone; analysis of cases reclassified as synovial sarcoma and solitary fibrous tumor of bone. Am J Surg Pathol. 34(6):777-83, 2010
Fitzpatrick D et al: Intradural hemangiopericytoma of the lumbar spine: a rare entity. AJNR Am J Neuroradiol. 30(1):152-4, 2009
Park MS et al: New insights into the hemangiopericytoma/solitary fibrous tumor spectrum of tumors. Curr Opin Oncol. 21(4):327-31, 2009
Kashiwazaki D et al: Subpial hemangiopericytoma with marked extramedullary growth: case report. Neurosurgery. 61(6):E1336-7; discussion E1337, 2007
Gengler C et al: Solitary fibrous tumour and haemangiopericytoma: evolution of a concept. Histopathology. 48(1):63-74, 2006
Cox DP et al: Myopericytoma of the thoracic spine: a case report. Spine. 28(2):E30-2, 2003
Musacchio M et al: Posterior cervical haemangiopericytoma with intracranial and skull base extension. Diagnostic and therapeutic challenge of a rare hypervascular neoplasm. J Neuroradiol. 30(3):180-7, 2003
Woitzik J et al: Delayed manifestation of spinal metastasis: a special feature of hemangiopericytoma. Clin Neurol Neurosurg. 105(3):159-66, 2003
Akhaddar A et al: Thoracic epidural hemangiopericytoma. Case report. J Neurosurg Sci. 46(2):89-92; discussion 92, 2002
Betchen S et al: Intradural hemangiopericytoma of the lumbar spine: case report. Neurosurgery. 50(3):654-7, 2002
Ijiri K et al: Primary epidural hemangiopericytoma in the lumbar spine: a case report. Spine (Phila Pa 1976). 27(7):E189-92, 2002
Tayoro K et al: [Imaging of meningeal hemangiopericytomas] J Radiol. 83(4 Pt 1):459-65, 2002
Suzuki SO et al: Clinicopathological features of solitary fibrous tumor of the meninges: An immunohistochemical reappraisal of cases previously diagnosed to be fibrous meningioma or hemangiopericytoma. Pathol Int. 50(10):808-17, 2000
Nonaka M et al: Metastatic meningeal hemangiopericytoma of thoracic spine. Clin Neurol Neurosurg. 100(3):228-30, 1998
Lin YJ et al: Primary hemangiopericytoma in the axis bone: case report and review of literature. Neurosurgery. 39(2):397-9; discussion 399-400, 1996
Murphey MD et al: From the archives of the AFIP. Musculoskeletal angiomatous lesions: radiologic-pathologic correlation. Radiographics. 15(4):893-917, 1995
Kozlowski K et al: Primary sacral bone tumours in children (report of 16 cases with a short literature review). Australas Radiol. 34(2):142-9, 1990
Bridges LR et al: Haemangiopericytic meningioma of the sacral canal: a case report. J Neurol Neurosurg Psychiatry. 51(2):288-90, 1988
Cuccurullo L et al: Hemangiopericytoma of the cervical spine. A case report. Acta Neurol (Napoli). 6(6):472-81, 1984
Beadle GF et al: Treatment of advanced malignant hemangiopericytoma with combination adriamycin and DTIC: a report of four cases. J Surg Oncol. 22(3):167-70, 1983
Muraszko KM et al: Hemangiopericytomas of the spine. Neurosurgery. 10(4):473-9, 1982
Cappabianca P et al: Hemangiopericytoma of the spinal canal. Surg Neurol. 15(4):298-302, 1981
Anderson C et al: Skeletal metastases of an intracranial malignant hemangiopericytoma. Report of a case. J Bone Joint Surg Am. 62(1):145-8, 1980
Stern MB et al: Hemangiopericytoma of the cervical spine: report of an unusual case. Clin Orthop. (151):201-4, 1980
Subbarao K et al: Primary malignant neoplasms. Semin Roentgenol. 14(1):44-57, 1979
Harris DJ et al: Hemangiopericytoma of the spinal canal. Report of three cases. J Neurosurg. 49(6):914-20, 1978
Hart S et al: Haemangiopericytoma of the pre-sacral space. Br J Surg. 60(7):583-4, 1973
Baxter PJ et al: Haemangiopericytoma. Light and electron microscopy studies of a cerebral secondary tumour. Acta Neuropathol (Berl). 21(3):253-7, 1972
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