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Solitary Pulmonary Nodule
Melissa L. Rosado de Christenson, MD, FACR
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KEY FACTS

  • Terminology

    • Imaging

      • Top Differential Diagnoses

        • Clinical Issues

          • Diagnostic Checklist

            TERMINOLOGY

            • Abbreviations

              • Solitary pulmonary nodule (SPN)
              • Ground-glass nodule (GGN)
            • Definitions

              • Nodule: Single, focal spherical or ovoid opacity ≤ 3 cm
                • Solid: Soft tissue attenuation
                • Ground-glass (nonsolid): Visualization of parenchymal structures through nodule
                • Part-solid (semisolid): Solid and ground-glass components
                • Subsolid: Includes ground-glass and part-solid nodules
              • SPN may be earliest imaging manifestation of lung cancer

            IMAGING

            • General Features

              • Radiographic Findings

                • CT Findings

                  • Nuclear Medicine Findings

                    • Imaging Recommendations

                      DIFFERENTIAL DIAGNOSIS

                        CLINICAL ISSUES

                        • Presentation

                          • Risk Factors

                            DIAGNOSTIC CHECKLIST

                            • Consider

                              • Image Interpretation Pearls

                                • Reporting Tips

                                  • MIPS Considerations

                                    Selected References

                                    1. MIPS Measure 364: Optimizing Patient Exposure to Ionizing Radiation: Appropriateness: Follow-up CT Imaging for Incidentally Detected Pulmonary Nodules According to Recommended Guidelines. Centers for Medicare and Medicaid Services (CMS). 2021.
                                    2. Alpert JB et al: Imaging the Solitary Pulmonary Nodule. Clin Chest Med. 36(2):161-178, 2015
                                    3. Naidich DP et al: Recommendations for the management of subsolid pulmonary nodules detected at CT: a statement from the Fleischner Society. Radiology. 266(1):304-17, 2013
                                    4. Winer-Muram HT: The solitary pulmonary nodule. Radiology. 239(1):34-49, 2006
                                    5. MacMahon H et al: Guidelines for management of small pulmonary nodules detected on CT scans: a statement from the Fleischner Society. Radiology. 237(2):395-400, 2005
                                    Related Anatomy
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                                    Related Differential Diagnoses
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                                    References
                                    Tables

                                    Tables

                                    KEY FACTS

                                    • Terminology

                                      • Imaging

                                        • Top Differential Diagnoses

                                          • Clinical Issues

                                            • Diagnostic Checklist

                                              TERMINOLOGY

                                              • Abbreviations

                                                • Solitary pulmonary nodule (SPN)
                                                • Ground-glass nodule (GGN)
                                              • Definitions

                                                • Nodule: Single, focal spherical or ovoid opacity ≤ 3 cm
                                                  • Solid: Soft tissue attenuation
                                                  • Ground-glass (nonsolid): Visualization of parenchymal structures through nodule
                                                  • Part-solid (semisolid): Solid and ground-glass components
                                                  • Subsolid: Includes ground-glass and part-solid nodules
                                                • SPN may be earliest imaging manifestation of lung cancer

                                              IMAGING

                                              • General Features

                                                • Radiographic Findings

                                                  • CT Findings

                                                    • Nuclear Medicine Findings

                                                      • Imaging Recommendations

                                                        DIFFERENTIAL DIAGNOSIS

                                                          CLINICAL ISSUES

                                                          • Presentation

                                                            • Risk Factors

                                                              DIAGNOSTIC CHECKLIST

                                                              • Consider

                                                                • Image Interpretation Pearls

                                                                  • Reporting Tips

                                                                    • MIPS Considerations

                                                                      Selected References

                                                                      1. MIPS Measure 364: Optimizing Patient Exposure to Ionizing Radiation: Appropriateness: Follow-up CT Imaging for Incidentally Detected Pulmonary Nodules According to Recommended Guidelines. Centers for Medicare and Medicaid Services (CMS). 2021.
                                                                      2. Alpert JB et al: Imaging the Solitary Pulmonary Nodule. Clin Chest Med. 36(2):161-178, 2015
                                                                      3. Naidich DP et al: Recommendations for the management of subsolid pulmonary nodules detected at CT: a statement from the Fleischner Society. Radiology. 266(1):304-17, 2013
                                                                      4. Winer-Muram HT: The solitary pulmonary nodule. Radiology. 239(1):34-49, 2006
                                                                      5. MacMahon H et al: Guidelines for management of small pulmonary nodules detected on CT scans: a statement from the Fleischner Society. Radiology. 237(2):395-400, 2005