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Solitary Pulmonary Nodule
Pavani Thotakura, MD; Hollins Clark, MD
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KEY FACTS

  • Terminology

    • Top Differential Diagnoses

      TERMINOLOGY

      • Definitions

        • Solitary pulmonary nodule (SPN)
          • Single, small (< 3 cm), solid or subsolid parenchymal opacity
          • Differential diagnosis
            • Neoplasm
            • Infection
            • Inflammation
            • Vascular anomalies
            • Congenital anomalies

      IMAGING

      • F-18 FDG PET/CT Findings

        • CT Findings

          DIFFERENTIAL DIAGNOSIS

            PATHOLOGY

            • General Features

              CLINICAL ISSUES

              • Presentation

                • Natural History & Prognosis

                  DIAGNOSTIC CHECKLIST

                  • Image Interpretation Pearls

                    • Reporting Tips

                      Selected References

                      1. Ruilong Z et al: Diagnostic value of 18F-FDG-PET/CT for the evaluation of solitary pulmonary nodules: a systematic review and meta-analysis. Nucl Med Commun. 38(1):67-75, 2017
                      2. Zukotynski KA et al: Molecular imaging and precision medicine in lung cancer. PET Clin. 12(1):53-62, 2017
                      3. Truong MT et al: Update in the evaluation of the solitary pulmonary nodule. Radiographics. 34(6):1658-79, 2014
                      4. Naidich DP et al: Recommendations for the management of subsolid pulmonary nodules detected at CT: a statement from the Fleischner Society. Radiology. 266(1):304-17, 2013
                      5. MacMahon H et al: Guidelines for management of small pulmonary nodules detected on CT scans: a statement from the Fleischner Society. Radiology. 237(2):395-400, 2005
                      6. Erasmus JJ et al: Solitary pulmonary nodules: Part I. Morphologic evaluation for differentiation of benign and malignant lesions. Radiographics. 20(1):43-58, 2000
                      7. Erasmus JJ et al: Solitary pulmonary nodules: Part II. Evaluation of the indeterminate nodule. Radiographics. 20(1):59-66, 2000
                      8. Lowe VJ et al: Prospective investigation of positron emission tomography in lung nodules. J Clin Oncol. 16(3):1075-84, 1998
                      Related Anatomy
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                      Related Differential Diagnoses
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                      References
                      Tables

                      Tables

                      KEY FACTS

                      • Terminology

                        • Top Differential Diagnoses

                          TERMINOLOGY

                          • Definitions

                            • Solitary pulmonary nodule (SPN)
                              • Single, small (< 3 cm), solid or subsolid parenchymal opacity
                              • Differential diagnosis
                                • Neoplasm
                                • Infection
                                • Inflammation
                                • Vascular anomalies
                                • Congenital anomalies

                          IMAGING

                          • F-18 FDG PET/CT Findings

                            • CT Findings

                              DIFFERENTIAL DIAGNOSIS

                                PATHOLOGY

                                • General Features

                                  CLINICAL ISSUES

                                  • Presentation

                                    • Natural History & Prognosis

                                      DIAGNOSTIC CHECKLIST

                                      • Image Interpretation Pearls

                                        • Reporting Tips

                                          Selected References

                                          1. Ruilong Z et al: Diagnostic value of 18F-FDG-PET/CT for the evaluation of solitary pulmonary nodules: a systematic review and meta-analysis. Nucl Med Commun. 38(1):67-75, 2017
                                          2. Zukotynski KA et al: Molecular imaging and precision medicine in lung cancer. PET Clin. 12(1):53-62, 2017
                                          3. Truong MT et al: Update in the evaluation of the solitary pulmonary nodule. Radiographics. 34(6):1658-79, 2014
                                          4. Naidich DP et al: Recommendations for the management of subsolid pulmonary nodules detected at CT: a statement from the Fleischner Society. Radiology. 266(1):304-17, 2013
                                          5. MacMahon H et al: Guidelines for management of small pulmonary nodules detected on CT scans: a statement from the Fleischner Society. Radiology. 237(2):395-400, 2005
                                          6. Erasmus JJ et al: Solitary pulmonary nodules: Part I. Morphologic evaluation for differentiation of benign and malignant lesions. Radiographics. 20(1):43-58, 2000
                                          7. Erasmus JJ et al: Solitary pulmonary nodules: Part II. Evaluation of the indeterminate nodule. Radiographics. 20(1):59-66, 2000
                                          8. Lowe VJ et al: Prospective investigation of positron emission tomography in lung nodules. J Clin Oncol. 16(3):1075-84, 1998