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Specimen Imaging
Reni Butler, MD; Wendie A. Berg, MD, PhD, FACR, FSBI
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KEY FACTS

  • Procedure

    • Post Procedure

      TERMINOLOGY

      • Definitions

        • Imaging of surgical specimen or core needle biopsy (CNB) samples to confirm presence of targeted lesion
        • Usually single-view magnification radiography (XR)
        • Digital breast tomosynthesis (DBT) or US, as needed

      PREPROCEDURE

      • Indications

        • Getting Started

          PROCEDURE

          • Patient Position/Location

            • Equipment Preparation

              • Procedure Steps

                • Findings and Reporting

                  • Alternative Procedures/Therapies

                    POST PROCEDURE

                    • Expected Outcome

                      • Things to Do

                        • Things to Avoid

                          OUTCOMES

                          • Problems

                            • Complications

                              Selected References

                              1. Polat YD et al: The role of tomosynthesis in intraoperative specimen evaluation. Breast J. 24(6):992-6, 2018
                              2. Amer HA et al: Digital breast tomosynthesis versus full-field digital mammography-which modality provides more accurate prediction of margin status in specimen radiography? Eur J Radiol. 93:258-64, 2017
                              3. Urano M et al: Digital mammography versus digital breast tomosynthesis for detection of breast cancer in the intraoperative specimen during breast-conserving surgery. Breast Cancer. 23(5):706-11, 2016
                              4. Gümüş H et al: Breast microcalcification: diagnostic value of calcified and non-calcified cores on specimen radiographs. Breast J. 19(2):156-61, 2013
                              5. Britton PD et al: Breast surgical specimen radiographs: how reliable are they? Eur J Radiol. 79(2):245-9, 2011
                              6. Dooley WC et al: Understanding the mechanisms creating false positive lumpectomy margins. Am J Surg. 190(4):606-8, 2005
                              7. Méndez JE et al: Tissue compression is not necessary for needle-localized lesion identification. Am J Surg. 190(4):580-2, 2005
                              8. Margolin FR et al: Stereotactic core breast biopsy of malignant calcifications: diagnostic yield of cores with and cores without calcifications on specimen radiographs. Radiology. 233(1):251-4, 2004
                              9. Liberman L et al: To excise or to sample the mammographic target: what is the goal of stereotactic 11-gauge vacuum-assisted breast biopsy? AJR Am J Roentgenol. 179(3):679-83, 2002
                              10. Berg WA et al: Predictive value of specimen radiography for core needle biopsy of noncalcified breast masses. AJR Am J Roentgenol. 171(6):1671-8, 1998
                              11. Homer MJ et al: Radiography of the surgical breast biopsy specimen. AJR Am J Roentgenol. 171(5):1197-9, 1998
                              12. D'Orsi CJ: Management of the breast specimen. Radiology. 194(2):297-302, 1995
                              13. Lee CH et al: Detecting residual tumor after excisional biopsy of impalpable breast carcinoma: efficacy of comparing preoperative mammograms with radiographs of the biopsy specimen. AJR Am J Roentgenol. 164(1):81-6, 1995
                              14. Liberman L et al: Radiography of microcalcifications in stereotaxic mammary core biopsy specimens. Radiology. 190(1):223-5, 1994
                              15. D'Orsi CJ et al: Breast specimen microcalcifications: radiographic validation and pathologic-radiologic correlation. Radiology. 180(2):397-401, 1991
                              16. Stomper PC et al: Efficacy of specimen radiography of clinically occult noncalcified breast lesions. AJR Am J Roentgenol. 151(1):43-7, 1988
                              Related Anatomy
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                              Related Differential Diagnoses
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                              References
                              Tables

                              Tables

                              KEY FACTS

                              • Procedure

                                • Post Procedure

                                  TERMINOLOGY

                                  • Definitions

                                    • Imaging of surgical specimen or core needle biopsy (CNB) samples to confirm presence of targeted lesion
                                    • Usually single-view magnification radiography (XR)
                                    • Digital breast tomosynthesis (DBT) or US, as needed

                                  PREPROCEDURE

                                  • Indications

                                    • Getting Started

                                      PROCEDURE

                                      • Patient Position/Location

                                        • Equipment Preparation

                                          • Procedure Steps

                                            • Findings and Reporting

                                              • Alternative Procedures/Therapies

                                                POST PROCEDURE

                                                • Expected Outcome

                                                  • Things to Do

                                                    • Things to Avoid

                                                      OUTCOMES

                                                      • Problems

                                                        • Complications

                                                          Selected References

                                                          1. Polat YD et al: The role of tomosynthesis in intraoperative specimen evaluation. Breast J. 24(6):992-6, 2018
                                                          2. Amer HA et al: Digital breast tomosynthesis versus full-field digital mammography-which modality provides more accurate prediction of margin status in specimen radiography? Eur J Radiol. 93:258-64, 2017
                                                          3. Urano M et al: Digital mammography versus digital breast tomosynthesis for detection of breast cancer in the intraoperative specimen during breast-conserving surgery. Breast Cancer. 23(5):706-11, 2016
                                                          4. Gümüş H et al: Breast microcalcification: diagnostic value of calcified and non-calcified cores on specimen radiographs. Breast J. 19(2):156-61, 2013
                                                          5. Britton PD et al: Breast surgical specimen radiographs: how reliable are they? Eur J Radiol. 79(2):245-9, 2011
                                                          6. Dooley WC et al: Understanding the mechanisms creating false positive lumpectomy margins. Am J Surg. 190(4):606-8, 2005
                                                          7. Méndez JE et al: Tissue compression is not necessary for needle-localized lesion identification. Am J Surg. 190(4):580-2, 2005
                                                          8. Margolin FR et al: Stereotactic core breast biopsy of malignant calcifications: diagnostic yield of cores with and cores without calcifications on specimen radiographs. Radiology. 233(1):251-4, 2004
                                                          9. Liberman L et al: To excise or to sample the mammographic target: what is the goal of stereotactic 11-gauge vacuum-assisted breast biopsy? AJR Am J Roentgenol. 179(3):679-83, 2002
                                                          10. Berg WA et al: Predictive value of specimen radiography for core needle biopsy of noncalcified breast masses. AJR Am J Roentgenol. 171(6):1671-8, 1998
                                                          11. Homer MJ et al: Radiography of the surgical breast biopsy specimen. AJR Am J Roentgenol. 171(5):1197-9, 1998
                                                          12. D'Orsi CJ: Management of the breast specimen. Radiology. 194(2):297-302, 1995
                                                          13. Lee CH et al: Detecting residual tumor after excisional biopsy of impalpable breast carcinoma: efficacy of comparing preoperative mammograms with radiographs of the biopsy specimen. AJR Am J Roentgenol. 164(1):81-6, 1995
                                                          14. Liberman L et al: Radiography of microcalcifications in stereotaxic mammary core biopsy specimens. Radiology. 190(1):223-5, 1994
                                                          15. D'Orsi CJ et al: Breast specimen microcalcifications: radiographic validation and pathologic-radiologic correlation. Radiology. 180(2):397-401, 1991
                                                          16. Stomper PC et al: Efficacy of specimen radiography of clinically occult noncalcified breast lesions. AJR Am J Roentgenol. 151(1):43-7, 1988