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KEY FACTS
Terminology
Imaging
Top Differential Diagnoses
Pathology
Clinical Issues
TERMINOLOGY
Synonyms
- Stellate margins
Definitions
- Sharp lines radiating from margin of mass
- May have associated architectural distortion: Retraction of parenchyma and tethering of Cooper ligaments
- Can be isolated finding (without central mass)
IMAGING
General Features
Mammographic Findings
Ultrasonographic Findings
MR Findings
Imaging Recommendations
DIFFERENTIAL DIAGNOSIS
PATHOLOGY
General Features
Microscopic Features
CLINICAL ISSUES
Presentation
Natural History & Prognosis
DIAGNOSTIC CHECKLIST
Consider
Image Interpretation Pearls
Selected References
- Wu T et al: Identification of a correlation between the sonographic appearance and molecular subtype of invasive breast cancer: a review of 311 cases. Clin Imaging. 53:179-85, 2019
- Gity M et al: Diagnostic investigation of breast magnetic resonance imaging in malignant and benign mass lesions. Arch Med Sci. 14(5):1061-9, 2018
- Vijapura C et al: Imaging features of nonmalignant and malignant architectural distortion detected By Tomosynthesis. AJR Am J Roentgenol. 211(6):1397-1404, 2018
- Wen X et al: Correlations between ultrasonographic findings of invasive lobular carcinoma of the breast and intrinsic subtypes. Ultraschall Med. ePub, 2018
- Woodard GA et al: Qualitative radiogenomics: association between oncotype DX test recurrence score and BI-RADS mammographic and breast MR imaging features. Radiology. 286(1):60-70, 2018
- Au FW et al: Histological grade and immunohistochemical biomarkers of breast cancer: correlation to ultrasound features. J Ultrasound Med. 36(9):1883-94, 2017
- Lee SH et al: Imaging features of breast cancers on digital breast tomosynthesis according to molecular subtype: association with breast cancer detection. Br J Radiol. 90(1080):20170470, 2017
- Navarro Vilar L et al: MR imaging findings in molecular subtypes of breast cancer according to BIRADS system. Breast J. 23(4):421-8, 2017
- Houssami N et al: Digital breast tomosynthesis (3D-mammography) screening: A pictorial review of screen-detected cancers and false recalls attributed to tomosynthesis in prospective screening trials. Breast. 26:119-34, 2016
- Kamal RM et al: Can we apply the MRI BI-RADS lexicon morphology descriptors on contrast-enhanced spectral mammography? Br J Radiol. 20160157, 2016
- Liu S et al: Is there a correlation between the presence of a spiculated mass on mammogram and luminal a subtype breast cancer? Korean J Radiol. 17(6):846-52, 2016
- Irshad A et al: Assessing the role of ultrasound in predicting the biological behavior of breast cancer. AJR Am J Roentgenol. 200(2):284-90, 2013
- Mendelson EB et al: Breast Imaging Reporting and Data System, BI-RADS: Ultrasound. 2nd ed. Reston, VA: American College of Radiology, 2013
- Morris EA et al: Breast Imaging Reporting and Data System, BI-RADS: MRI. 2nd ed. Reston, VA: American College of Radiology, 2013
- Sickles EA et al: Breast Imaging Reporting and Data System, BI-RADS: Mammography. 5th ed. Reston, VA: American College of Radiology, 2013
- Skaane P et al: Comparison of digital mammography alone and digital mammography plus tomosynthesis in a population-based screening program. Radiology. 267(1):47-56, 2013
- Blaichman J et al: Sonographic appearance of invasive ductal carcinoma of the breast according to histologic grade. AJR Am J Roentgenol. 199(3):W402-8, 2012
- Linda A et al: Nonsurgical management of high-risk lesions diagnosed at core needle biopsy: can malignancy be ruled out safely with breast MRI? AJR Am J Roentgenol. 198(2):272-80, 2012
- Brennan ME et al: Magnetic resonance imaging screening of the contralateral breast in women with newly diagnosed breast cancer: systematic review and meta-analysis of incremental cancer detection and impact on surgical management. J Clin Oncol. 27(33):5640-9, 2009
- Wang Y et al: Estrogen receptor-negative invasive breast cancer: imaging features of tumors with and without human epidermal growth factor receptor type 2 overexpression. Radiology. 246(2):367-75, 2008
- Alexander MC et al: Association of stellate mammographic pattern with survival in small invasive breast tumors. AJR Am J Roentgenol. 187(1):29-37, 2006
- Evans AJ et al: Is mammographic spiculation an independent, good prognostic factor in screening-detected invasive breast cancer? AJR Am J Roentgenol. 187(5):1377-80, 2006
- Hong AS et al: BI-RADS for sonography: positive and negative predictive values of sonographic features. AJR Am J Roentgenol. 184(4):1260-5, 2005
- Liberman L et al: MR imaging of the ipsilateral breast in women with percutaneously proven breast cancer. AJR Am J Roentgenol. 180(4):901-10, 2003
- Tabár L et al: The Swedish Two-County Trial twenty years later. Updated mortality results and new insights from long-term follow-up. Radiol Clin North Am. 38(4):625-51, 2000
- Liberman L et al: The breast imaging reporting and data system: positive predictive value of mammographic features and final assessment categories. AJR Am J Roentgenol. 171(1):35-40, 1998
- Stavros AT et al: Solid breast nodules: use of sonography to distinguish between benign and malignant lesions. Radiology. 196(1):123-34, 1995
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Tables
KEY FACTS
Terminology
Imaging
Top Differential Diagnoses
Pathology
Clinical Issues
TERMINOLOGY
Synonyms
- Stellate margins
Definitions
- Sharp lines radiating from margin of mass
- May have associated architectural distortion: Retraction of parenchyma and tethering of Cooper ligaments
- Can be isolated finding (without central mass)
IMAGING
General Features
Mammographic Findings
Ultrasonographic Findings
MR Findings
Imaging Recommendations
DIFFERENTIAL DIAGNOSIS
PATHOLOGY
General Features
Microscopic Features
CLINICAL ISSUES
Presentation
Natural History & Prognosis
DIAGNOSTIC CHECKLIST
Consider
Image Interpretation Pearls
Selected References
- Wu T et al: Identification of a correlation between the sonographic appearance and molecular subtype of invasive breast cancer: a review of 311 cases. Clin Imaging. 53:179-85, 2019
- Gity M et al: Diagnostic investigation of breast magnetic resonance imaging in malignant and benign mass lesions. Arch Med Sci. 14(5):1061-9, 2018
- Vijapura C et al: Imaging features of nonmalignant and malignant architectural distortion detected By Tomosynthesis. AJR Am J Roentgenol. 211(6):1397-1404, 2018
- Wen X et al: Correlations between ultrasonographic findings of invasive lobular carcinoma of the breast and intrinsic subtypes. Ultraschall Med. ePub, 2018
- Woodard GA et al: Qualitative radiogenomics: association between oncotype DX test recurrence score and BI-RADS mammographic and breast MR imaging features. Radiology. 286(1):60-70, 2018
- Au FW et al: Histological grade and immunohistochemical biomarkers of breast cancer: correlation to ultrasound features. J Ultrasound Med. 36(9):1883-94, 2017
- Lee SH et al: Imaging features of breast cancers on digital breast tomosynthesis according to molecular subtype: association with breast cancer detection. Br J Radiol. 90(1080):20170470, 2017
- Navarro Vilar L et al: MR imaging findings in molecular subtypes of breast cancer according to BIRADS system. Breast J. 23(4):421-8, 2017
- Houssami N et al: Digital breast tomosynthesis (3D-mammography) screening: A pictorial review of screen-detected cancers and false recalls attributed to tomosynthesis in prospective screening trials. Breast. 26:119-34, 2016
- Kamal RM et al: Can we apply the MRI BI-RADS lexicon morphology descriptors on contrast-enhanced spectral mammography? Br J Radiol. 20160157, 2016
- Liu S et al: Is there a correlation between the presence of a spiculated mass on mammogram and luminal a subtype breast cancer? Korean J Radiol. 17(6):846-52, 2016
- Irshad A et al: Assessing the role of ultrasound in predicting the biological behavior of breast cancer. AJR Am J Roentgenol. 200(2):284-90, 2013
- Mendelson EB et al: Breast Imaging Reporting and Data System, BI-RADS: Ultrasound. 2nd ed. Reston, VA: American College of Radiology, 2013
- Morris EA et al: Breast Imaging Reporting and Data System, BI-RADS: MRI. 2nd ed. Reston, VA: American College of Radiology, 2013
- Sickles EA et al: Breast Imaging Reporting and Data System, BI-RADS: Mammography. 5th ed. Reston, VA: American College of Radiology, 2013
- Skaane P et al: Comparison of digital mammography alone and digital mammography plus tomosynthesis in a population-based screening program. Radiology. 267(1):47-56, 2013
- Blaichman J et al: Sonographic appearance of invasive ductal carcinoma of the breast according to histologic grade. AJR Am J Roentgenol. 199(3):W402-8, 2012
- Linda A et al: Nonsurgical management of high-risk lesions diagnosed at core needle biopsy: can malignancy be ruled out safely with breast MRI? AJR Am J Roentgenol. 198(2):272-80, 2012
- Brennan ME et al: Magnetic resonance imaging screening of the contralateral breast in women with newly diagnosed breast cancer: systematic review and meta-analysis of incremental cancer detection and impact on surgical management. J Clin Oncol. 27(33):5640-9, 2009
- Wang Y et al: Estrogen receptor-negative invasive breast cancer: imaging features of tumors with and without human epidermal growth factor receptor type 2 overexpression. Radiology. 246(2):367-75, 2008
- Alexander MC et al: Association of stellate mammographic pattern with survival in small invasive breast tumors. AJR Am J Roentgenol. 187(1):29-37, 2006
- Evans AJ et al: Is mammographic spiculation an independent, good prognostic factor in screening-detected invasive breast cancer? AJR Am J Roentgenol. 187(5):1377-80, 2006
- Hong AS et al: BI-RADS for sonography: positive and negative predictive values of sonographic features. AJR Am J Roentgenol. 184(4):1260-5, 2005
- Liberman L et al: MR imaging of the ipsilateral breast in women with percutaneously proven breast cancer. AJR Am J Roentgenol. 180(4):901-10, 2003
- Tabár L et al: The Swedish Two-County Trial twenty years later. Updated mortality results and new insights from long-term follow-up. Radiol Clin North Am. 38(4):625-51, 2000
- Liberman L et al: The breast imaging reporting and data system: positive predictive value of mammographic features and final assessment categories. AJR Am J Roentgenol. 171(1):35-40, 1998
- Stavros AT et al: Solid breast nodules: use of sonography to distinguish between benign and malignant lesions. Radiology. 196(1):123-34, 1995
