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Spindle Cell Oncocytoma
Anne G. Osborn, MD, FACR; Karen L. Salzman, MD
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KEY FACTS

  • Terminology

    • Imaging

      • Top Differential Diagnoses

        • Pathology

          • Clinical Issues

            TERMINOLOGY

            • Abbreviations

              • Spindle cell oncocytoma (SCO)
            • Synonyms

              • Spindle cell oncocytoma of posterior pituitary
            • Definitions

              • In 2017, WHO established that pituicytoma, granular cell tumor (GCT), and spindle cell oncocytoma (SCO) are posterior pituitary tumors (PPTs)
                • Probably arise from pituicytes
                • May constitute spectrum of a unique histopathological entity

            IMAGING

            • General Features

              • Imaging Recommendations

                • CT Findings

                  • MR Findings

                    DIFFERENTIAL DIAGNOSIS

                      PATHOLOGY

                      • General Features

                        • Staging, Grading, & Classification

                          • Gross Pathologic & Surgical Features

                            • Microscopic Features

                              CLINICAL ISSUES

                              • Presentation

                                • Demographics

                                  • Natural History & Prognosis

                                    • Treatment

                                      Selected References

                                      1. Borg A et al: Tumors of the neurohypophysis: One unit's experience and literature review. World Neurosurg. 134:e968-78, 2020
                                      2. Li Y et al: Imaging characteristics of a hypervascular pituitary spindle cell oncocytoma on magnetic resonance imaging and digital subtraction angiography. World Neurosurg. 133:56-9, 2020
                                      3. Guerrero-Pérez F et al: Posterior pituitary tumours: the spectrum of a unique entity. A clinical and histological study of a large case series. Endocrine. 63(1):36-43, 2019
                                      4. Giantini Larsen AM et al: Spindle cell oncocytoma of the pituitary gland. J Neurosurg. 131(2):517-25, 2018
                                      5. Mathkour M et al: Spindle cell oncocytoma of the pituitary gland. J Neurosurg Sci. 61(5):554-7, 2017
                                      Related Anatomy
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                                      Related Differential Diagnoses
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                                      References
                                      Tables

                                      Tables

                                      KEY FACTS

                                      • Terminology

                                        • Imaging

                                          • Top Differential Diagnoses

                                            • Pathology

                                              • Clinical Issues

                                                TERMINOLOGY

                                                • Abbreviations

                                                  • Spindle cell oncocytoma (SCO)
                                                • Synonyms

                                                  • Spindle cell oncocytoma of posterior pituitary
                                                • Definitions

                                                  • In 2017, WHO established that pituicytoma, granular cell tumor (GCT), and spindle cell oncocytoma (SCO) are posterior pituitary tumors (PPTs)
                                                    • Probably arise from pituicytes
                                                    • May constitute spectrum of a unique histopathological entity

                                                IMAGING

                                                • General Features

                                                  • Imaging Recommendations

                                                    • CT Findings

                                                      • MR Findings

                                                        DIFFERENTIAL DIAGNOSIS

                                                          PATHOLOGY

                                                          • General Features

                                                            • Staging, Grading, & Classification

                                                              • Gross Pathologic & Surgical Features

                                                                • Microscopic Features

                                                                  CLINICAL ISSUES

                                                                  • Presentation

                                                                    • Demographics

                                                                      • Natural History & Prognosis

                                                                        • Treatment

                                                                          Selected References

                                                                          1. Borg A et al: Tumors of the neurohypophysis: One unit's experience and literature review. World Neurosurg. 134:e968-78, 2020
                                                                          2. Li Y et al: Imaging characteristics of a hypervascular pituitary spindle cell oncocytoma on magnetic resonance imaging and digital subtraction angiography. World Neurosurg. 133:56-9, 2020
                                                                          3. Guerrero-Pérez F et al: Posterior pituitary tumours: the spectrum of a unique entity. A clinical and histological study of a large case series. Endocrine. 63(1):36-43, 2019
                                                                          4. Giantini Larsen AM et al: Spindle cell oncocytoma of the pituitary gland. J Neurosurg. 131(2):517-25, 2018
                                                                          5. Mathkour M et al: Spindle cell oncocytoma of the pituitary gland. J Neurosurg Sci. 61(5):554-7, 2017