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Splenic Infection and Abscess
Siva P. Raman, MD
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KEY FACTS

  • Imaging

    • Top Differential Diagnoses

      • Pathology

        TERMINOLOGY

        • Definitions

          • Splenic abscess: Loculated collection of infected fluid or liquefied pus within splenic parenchyma

        IMAGING

        • General Features

          • Radiographic Findings

            • CT Findings

              • MR Findings

                • Ultrasonographic Findings

                  • Imaging Recommendations

                    DIFFERENTIAL DIAGNOSIS

                      PATHOLOGY

                      • General Features

                        CLINICAL ISSUES

                        • Presentation

                          • Demographics

                            • Natural History & Prognosis

                              • Treatment

                                DIAGNOSTIC CHECKLIST

                                • Consider

                                  • Image Interpretation Pearls

                                    Selected References

                                    1. O'Connor LF et al: Splenic abscess: characterizing management and outcomes for a rare disease. Am Surg. 86(3):e130-3, 2020
                                    2. Coco D et al: Indications for surgery in non-traumatic spleen disease. Open Access Maced J Med Sci. 7(17):2958-60, 2019
                                    3. Mehta P et al: Radiological manifestations of hydatid disease and its complications. Trop Parasitol. 6(2):103-12, 2016
                                    4. Faruque AV et al: Isolated splenic abscess in children, role of splenic preservation. Pediatr Surg Int. 29(8):787-90, 2013
                                    5. Tonolini M et al: Nontraumatic splenic emergencies: cross-sectional imaging findings and triage. Emerg Radiol. 20(4):323-32, 2013
                                    6. Sreekar H et al: A retrospective study of 75 cases of splenic abscess. Indian J Surg. 73(6):398-402, 2011
                                    7. Nunweiler CG et al: The imaging features of nontuberculous mycobacterial immune reconstitution syndrome. J Comput Assist Tomogr. 33(2):242-6, 2009
                                    8. Lombardi A et al: Splenic abscess due to Streptococcus anginosus. Case report. G Chir. 29(8-9):359-61, 2008
                                    9. Kamaya A et al: Multiple lesions of the spleen: differential diagnosis of cystic and solid lesions. Semin Ultrasound CT MR. 27(5):389-403, 2006
                                    10. Tasar M et al: Computed tomography-guided percutaneous drainage of splenic abscesses. Clin Imaging. 28(1):44-8, 2004
                                    11. Chiang IS et al: Splenic abscesses: review of 29 cases. Kaohsiung J Med Sci. 19(10):510-5, 2003
                                    12. Kaushik R et al: Splenic abscess. Trop Doct. 32(4):246-7, 2002
                                    13. Ng KK et al: Splenic abscess: diagnosis and management. Hepatogastroenterology. 49(44):567-71, 2002
                                    14. Thanos L et al: Percutaneous CT-guided drainage of splenic abscess. AJR Am J Roentgenol. 179(3):629-32, 2002
                                    15. Green BT: Splenic abscess: report of six cases and review of the literature. Am Surg. 67(1):80-5, 2001
                                    16. Loualidi A et al: Splenic abscess caused by Peptostreptococcus species, diagnosed with the aid of abdominal computerized tomography and treated with percutaneous drainage and antibiotics: a case report. Neth J Med. 59(6):280-5, 2001
                                    17. Drevelengas A: The spleen in infectious disorders. JBR-BTR. 83(4):208-10, 2000
                                    18. Frumiento C et al: Complications of splenic injuries: expansion of the nonoperative theorem. J Pediatr Surg. 35(5):788-91, 2000
                                    19. Mehanna D et al: Cat scratch disease presenting as splenic abscess. Aust N Z J Surg. 70(8):622-4, 2000
                                    20. Murray AW et al: A case of multiple splenic abscesses managed non-operatively. J R Coll Surg Edinb. 45(3):189-91, 2000
                                    21. Poggi SH et al: Puerperal splenic abscess. Obstet Gynecol. 96(5 Pt 2):842, 2000
                                    22. Smyrniotis V et al: Splenic abscess. An old disease with new interest. Dig Surg. 17(4):354-7, 2000
                                    23. Bernabeu-Wittel M et al: Etiology, clinical features and outcome of splenic microabscesses in HIV-infected patients with prolonged fever. Eur J Clin Microbiol Infect Dis. 18(5):324-9, 1999
                                    24. Duggal RK et al: Splenic abscess as a complication of acute pancreatitis. J Assoc Physicians India. 47(3):338-9, 1999
                                    25. Nakao A et al: Portal venous gas associated with splenic abscess secondary to colon cancer. Anticancer Res. 19(6C):5641-4, 1999
                                    26. Al-Salem AH et al: Splenic abscess and sickle cell disease. Am J Hematol. 58(2):100-4, 1998
                                    27. Alterman P et al: Splenic abscess in geriatric care. J Am Geriatr Soc. 46(11):1481-3, 1998
                                    28. de Bree E et al: Splenic abscess: a diagnostic and therapeutic challenge. Acta Chir Belg. 98(5):199-202, 1998
                                    29. Wang Y et al: CT findings in splenic tuberculosis. J Belge Radiol. 81(2):90-1, 1998
                                    Related Anatomy
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                                    Related Differential Diagnoses
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                                    References
                                    Tables

                                    Tables

                                    KEY FACTS

                                    • Imaging

                                      • Top Differential Diagnoses

                                        • Pathology

                                          TERMINOLOGY

                                          • Definitions

                                            • Splenic abscess: Loculated collection of infected fluid or liquefied pus within splenic parenchyma

                                          IMAGING

                                          • General Features

                                            • Radiographic Findings

                                              • CT Findings

                                                • MR Findings

                                                  • Ultrasonographic Findings

                                                    • Imaging Recommendations

                                                      DIFFERENTIAL DIAGNOSIS

                                                        PATHOLOGY

                                                        • General Features

                                                          CLINICAL ISSUES

                                                          • Presentation

                                                            • Demographics

                                                              • Natural History & Prognosis

                                                                • Treatment

                                                                  DIAGNOSTIC CHECKLIST

                                                                  • Consider

                                                                    • Image Interpretation Pearls

                                                                      Selected References

                                                                      1. O'Connor LF et al: Splenic abscess: characterizing management and outcomes for a rare disease. Am Surg. 86(3):e130-3, 2020
                                                                      2. Coco D et al: Indications for surgery in non-traumatic spleen disease. Open Access Maced J Med Sci. 7(17):2958-60, 2019
                                                                      3. Mehta P et al: Radiological manifestations of hydatid disease and its complications. Trop Parasitol. 6(2):103-12, 2016
                                                                      4. Faruque AV et al: Isolated splenic abscess in children, role of splenic preservation. Pediatr Surg Int. 29(8):787-90, 2013
                                                                      5. Tonolini M et al: Nontraumatic splenic emergencies: cross-sectional imaging findings and triage. Emerg Radiol. 20(4):323-32, 2013
                                                                      6. Sreekar H et al: A retrospective study of 75 cases of splenic abscess. Indian J Surg. 73(6):398-402, 2011
                                                                      7. Nunweiler CG et al: The imaging features of nontuberculous mycobacterial immune reconstitution syndrome. J Comput Assist Tomogr. 33(2):242-6, 2009
                                                                      8. Lombardi A et al: Splenic abscess due to Streptococcus anginosus. Case report. G Chir. 29(8-9):359-61, 2008
                                                                      9. Kamaya A et al: Multiple lesions of the spleen: differential diagnosis of cystic and solid lesions. Semin Ultrasound CT MR. 27(5):389-403, 2006
                                                                      10. Tasar M et al: Computed tomography-guided percutaneous drainage of splenic abscesses. Clin Imaging. 28(1):44-8, 2004
                                                                      11. Chiang IS et al: Splenic abscesses: review of 29 cases. Kaohsiung J Med Sci. 19(10):510-5, 2003
                                                                      12. Kaushik R et al: Splenic abscess. Trop Doct. 32(4):246-7, 2002
                                                                      13. Ng KK et al: Splenic abscess: diagnosis and management. Hepatogastroenterology. 49(44):567-71, 2002
                                                                      14. Thanos L et al: Percutaneous CT-guided drainage of splenic abscess. AJR Am J Roentgenol. 179(3):629-32, 2002
                                                                      15. Green BT: Splenic abscess: report of six cases and review of the literature. Am Surg. 67(1):80-5, 2001
                                                                      16. Loualidi A et al: Splenic abscess caused by Peptostreptococcus species, diagnosed with the aid of abdominal computerized tomography and treated with percutaneous drainage and antibiotics: a case report. Neth J Med. 59(6):280-5, 2001
                                                                      17. Drevelengas A: The spleen in infectious disorders. JBR-BTR. 83(4):208-10, 2000
                                                                      18. Frumiento C et al: Complications of splenic injuries: expansion of the nonoperative theorem. J Pediatr Surg. 35(5):788-91, 2000
                                                                      19. Mehanna D et al: Cat scratch disease presenting as splenic abscess. Aust N Z J Surg. 70(8):622-4, 2000
                                                                      20. Murray AW et al: A case of multiple splenic abscesses managed non-operatively. J R Coll Surg Edinb. 45(3):189-91, 2000
                                                                      21. Poggi SH et al: Puerperal splenic abscess. Obstet Gynecol. 96(5 Pt 2):842, 2000
                                                                      22. Smyrniotis V et al: Splenic abscess. An old disease with new interest. Dig Surg. 17(4):354-7, 2000
                                                                      23. Bernabeu-Wittel M et al: Etiology, clinical features and outcome of splenic microabscesses in HIV-infected patients with prolonged fever. Eur J Clin Microbiol Infect Dis. 18(5):324-9, 1999
                                                                      24. Duggal RK et al: Splenic abscess as a complication of acute pancreatitis. J Assoc Physicians India. 47(3):338-9, 1999
                                                                      25. Nakao A et al: Portal venous gas associated with splenic abscess secondary to colon cancer. Anticancer Res. 19(6C):5641-4, 1999
                                                                      26. Al-Salem AH et al: Splenic abscess and sickle cell disease. Am J Hematol. 58(2):100-4, 1998
                                                                      27. Alterman P et al: Splenic abscess in geriatric care. J Am Geriatr Soc. 46(11):1481-3, 1998
                                                                      28. de Bree E et al: Splenic abscess: a diagnostic and therapeutic challenge. Acta Chir Belg. 98(5):199-202, 1998
                                                                      29. Wang Y et al: CT findings in splenic tuberculosis. J Belge Radiol. 81(2):90-1, 1998