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Splenomegaly
Ali M. Tahvildari, MD
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KEY FACTS

  • Imaging

    • Top Differential Diagnoses

      • Pathology

        • Diagnostic Checklist

          TERMINOLOGY

          • Abbreviations

            • Splenomegaly (SMG), hypersplenism (HS)
          • Definitions

            • SMG: Increased splenic size, length > 13 cm in adults, weight > 250 g
            • HS: Clinical syndrome consisting of SMG and pancytopenia

          IMAGING

          • General Features

            • Ultrasonographic Findings

              • Radiographic Findings

                • CT Findings

                  • MR Findings

                    • Nuclear Medicine Findings

                      • Imaging Recommendations

                        DIFFERENTIAL DIAGNOSIS

                          PATHOLOGY

                          • General Features

                            CLINICAL ISSUES

                            • Presentation

                              • Natural History & Prognosis

                                • Treatment

                                  DIAGNOSTIC CHECKLIST

                                  • Consider

                                    • Image Interpretation Pearls

                                      Selected References

                                      1. Chiorean L et al: Ultrasonography of the spleen. Pictorial essay. Med Ultrason. 16(1):48-59, 2014
                                      2. Benter T et al: Sonography of the spleen. J Ultrasound Med. 30(9):1281-93, 2011
                                      3. Ehimwenma O et al: Determination of normal dimension of the spleen by ultrasound in an endemic tropical environment. Niger Med J. 52(3):198-203, 2011
                                      4. Spielmann AL et al: Sonographic evaluation of spleen size in tall healthy athletes. AJR Am J Roentgenol. 184(1):45-9, 2005
                                      5. Yetter EM et al: Estimating splenic volume: sonographic measurements correlated with helical CT determination. AJR Am J Roentgenol. 181(6):1615-20, 2003
                                      6. Lamb PM et al: Spleen size: how well do linear ultrasound measurements correlate with three-dimensional CT volume assessments? Br J Radiol. 75(895):573-7, 2002
                                      7. Freeman JL et al: CT of congenital and acquired abnormalities of the spleen. Radiographics. 13(3):597-610, 1993
                                      8. Doll M et al: [Clinical significance of sonographically detected splenomegaly.] Dtsch Med Wochenschr. 111(23):887-91, 1986
                                      Related Anatomy
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                                      Related Differential Diagnoses
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                                      References
                                      Tables

                                      Tables

                                      KEY FACTS

                                      • Imaging

                                        • Top Differential Diagnoses

                                          • Pathology

                                            • Diagnostic Checklist

                                              TERMINOLOGY

                                              • Abbreviations

                                                • Splenomegaly (SMG), hypersplenism (HS)
                                              • Definitions

                                                • SMG: Increased splenic size, length > 13 cm in adults, weight > 250 g
                                                • HS: Clinical syndrome consisting of SMG and pancytopenia

                                              IMAGING

                                              • General Features

                                                • Ultrasonographic Findings

                                                  • Radiographic Findings

                                                    • CT Findings

                                                      • MR Findings

                                                        • Nuclear Medicine Findings

                                                          • Imaging Recommendations

                                                            DIFFERENTIAL DIAGNOSIS

                                                              PATHOLOGY

                                                              • General Features

                                                                CLINICAL ISSUES

                                                                • Presentation

                                                                  • Natural History & Prognosis

                                                                    • Treatment

                                                                      DIAGNOSTIC CHECKLIST

                                                                      • Consider

                                                                        • Image Interpretation Pearls

                                                                          Selected References

                                                                          1. Chiorean L et al: Ultrasonography of the spleen. Pictorial essay. Med Ultrason. 16(1):48-59, 2014
                                                                          2. Benter T et al: Sonography of the spleen. J Ultrasound Med. 30(9):1281-93, 2011
                                                                          3. Ehimwenma O et al: Determination of normal dimension of the spleen by ultrasound in an endemic tropical environment. Niger Med J. 52(3):198-203, 2011
                                                                          4. Spielmann AL et al: Sonographic evaluation of spleen size in tall healthy athletes. AJR Am J Roentgenol. 184(1):45-9, 2005
                                                                          5. Yetter EM et al: Estimating splenic volume: sonographic measurements correlated with helical CT determination. AJR Am J Roentgenol. 181(6):1615-20, 2003
                                                                          6. Lamb PM et al: Spleen size: how well do linear ultrasound measurements correlate with three-dimensional CT volume assessments? Br J Radiol. 75(895):573-7, 2002
                                                                          7. Freeman JL et al: CT of congenital and acquired abnormalities of the spleen. Radiographics. 13(3):597-610, 1993
                                                                          8. Doll M et al: [Clinical significance of sonographically detected splenomegaly.] Dtsch Med Wochenschr. 111(23):887-91, 1986