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Squamous Cell Carcinoma
Bryan R. Foster, MD; Amir A. Borhani, MD
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KEY FACTS

  • Terminology

    • Imaging

      • Top Differential Diagnoses

        • Pathology

          • Clinical Issues

            TERMINOLOGY

            • Abbreviations

              • Squamous cell carcinoma (SCC)
            • Definitions

              • Rare malignant bladder epithelial neoplasm with pure squamous cell differentiation

            IMAGING

            • General Features

              • CT Findings

                • MR Findings

                  • Ultrasonographic Findings

                    • Imaging Recommendations

                      DIFFERENTIAL DIAGNOSIS

                        PATHOLOGY

                        • General Features

                          • Staging, Grading, & Classification

                            • Gross Pathologic & Surgical Features

                              • Microscopic Features

                                CLINICAL ISSUES

                                • Presentation

                                  • Demographics

                                    • Natural History & Prognosis

                                      • Treatment

                                        Selected References

                                        1. Deuker M et al: Bladder cancer: a comparison between non-urothelial variant histology and urothelial carcinoma across all stages and treatment modalities. Clin Genitourin Cancer. 19(1):60-8.e1, 2021
                                        2. Zaghloul MS et al: Urinary schistosomiasis and the associated bladder cancer: update. J Egypt Natl Canc Inst. 32(1):44, 2020
                                        3. Poturalski MJ et al: Squamous cell carcinoma of the bladder complicating schistosomiasis: AIRP best cases in radiologic-pathologic correlation. Radiographics. 37(2):500-4, 2017
                                        4. Willis D et al: Nonurothelial bladder cancer and rare variant histologies. Hematol Oncol Clin North Am. 29(2):237-52, 2015
                                        5. Mouli S et al: Imaging features of common and uncommon bladder neoplasms. Radiol Clin North Am. 50(2):301-16, vi, 2012
                                        6. Verma S et al: Urinary bladder cancer: role of MR imaging. Radiographics. 32(2):371-87, 2012
                                        7. Damjanov I et al: Histopathology of urinary bladder carcinoma: less common variants. Srp Arh Celok Lek. 139(9-10):693-9, 2011
                                        8. Dighe MK et al: Urinary bladder masses: techniques, imaging spectrum, and staging. J Comput Assist Tomogr. 35(4):411-24, 2011
                                        9. Pons F et al: Variant forms of bladder cancer: basic considerations on treatment approaches. Curr Oncol Rep. 13(3):216-21, 2011
                                        10. Wong-You-Cheong J et al: Neoplasms of the urinary bladder: radiologic-pathologic correlation. RadioGraphics 26: 553-80,2006
                                        11. Wong JT et al: Bladder squamous cell carcinoma. Radiographics. 24(3):855-60, 2004
                                        Related Anatomy
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                                        Related Differential Diagnoses
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                                        References
                                        Tables

                                        Tables

                                        KEY FACTS

                                        • Terminology

                                          • Imaging

                                            • Top Differential Diagnoses

                                              • Pathology

                                                • Clinical Issues

                                                  TERMINOLOGY

                                                  • Abbreviations

                                                    • Squamous cell carcinoma (SCC)
                                                  • Definitions

                                                    • Rare malignant bladder epithelial neoplasm with pure squamous cell differentiation

                                                  IMAGING

                                                  • General Features

                                                    • CT Findings

                                                      • MR Findings

                                                        • Ultrasonographic Findings

                                                          • Imaging Recommendations

                                                            DIFFERENTIAL DIAGNOSIS

                                                              PATHOLOGY

                                                              • General Features

                                                                • Staging, Grading, & Classification

                                                                  • Gross Pathologic & Surgical Features

                                                                    • Microscopic Features

                                                                      CLINICAL ISSUES

                                                                      • Presentation

                                                                        • Demographics

                                                                          • Natural History & Prognosis

                                                                            • Treatment

                                                                              Selected References

                                                                              1. Deuker M et al: Bladder cancer: a comparison between non-urothelial variant histology and urothelial carcinoma across all stages and treatment modalities. Clin Genitourin Cancer. 19(1):60-8.e1, 2021
                                                                              2. Zaghloul MS et al: Urinary schistosomiasis and the associated bladder cancer: update. J Egypt Natl Canc Inst. 32(1):44, 2020
                                                                              3. Poturalski MJ et al: Squamous cell carcinoma of the bladder complicating schistosomiasis: AIRP best cases in radiologic-pathologic correlation. Radiographics. 37(2):500-4, 2017
                                                                              4. Willis D et al: Nonurothelial bladder cancer and rare variant histologies. Hematol Oncol Clin North Am. 29(2):237-52, 2015
                                                                              5. Mouli S et al: Imaging features of common and uncommon bladder neoplasms. Radiol Clin North Am. 50(2):301-16, vi, 2012
                                                                              6. Verma S et al: Urinary bladder cancer: role of MR imaging. Radiographics. 32(2):371-87, 2012
                                                                              7. Damjanov I et al: Histopathology of urinary bladder carcinoma: less common variants. Srp Arh Celok Lek. 139(9-10):693-9, 2011
                                                                              8. Dighe MK et al: Urinary bladder masses: techniques, imaging spectrum, and staging. J Comput Assist Tomogr. 35(4):411-24, 2011
                                                                              9. Pons F et al: Variant forms of bladder cancer: basic considerations on treatment approaches. Curr Oncol Rep. 13(3):216-21, 2011
                                                                              10. Wong-You-Cheong J et al: Neoplasms of the urinary bladder: radiologic-pathologic correlation. RadioGraphics 26: 553-80,2006
                                                                              11. Wong JT et al: Bladder squamous cell carcinoma. Radiographics. 24(3):855-60, 2004