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Staging: Gastrointestinal Stromal Tumor (GIST)
Marc S. Tubay, MD
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8

Overview

  • General Comments

    • Classification

      Pathology

      • Routes Spread

        • General Features

          • Gross Pathology

            • Microscopic Features

              Imaging Findings

              • Detection

                • Staging

                  • Restaging

                    Clinical Issues

                    • Presentation

                      • Cancer History

                        • Treatment Options

                          Reporting Checklist

                          • T Staging

                            • N Staging

                              • M Staging

                                • Histologic Evaluation

                                  • Restaging

                                    Selected References

                                    1. American Joint Committee on Cancer: AJCC Cancer Staging Manual. 7th ed. New York: Springer. 175-80, 2010
                                    2. Agaimy A et al: Lymph node metastasis in gastrointestinal stromal tumours (GIST) occurs preferentially in young patients < or = 40 years: an overview based on our case material and the literature. Langenbecks Arch Surg. 394(2):375-81, 2009
                                    3. Wronski M et al: Gastrointestinal stromal tumors: ultrasonographic spectrum of the disease. J Ultrasound Med. 28(7):941-8, 2009
                                    4. Choi H: Response evaluation of gastrointestinal stromal tumors. Oncologist. 13 Suppl 2:4-7, 2008
                                    5. Badalamenti G et al: Gastrointestinal stromal tumors (GISTs): focus on histopathological diagnosis and biomolecular features. Ann Oncol. 18 Suppl 6:vi136-40, 2007
                                    6. Choi H et al: Correlation of computed tomography and positron emission tomography in patients with metastatic gastrointestinal stromal tumor treated at a single institution with imatinib mesylate: proposal of new computed tomography response criteria. J Clin Oncol. 25(13):1753-9, 2007
                                    7. Gutierrez JC et al: Optimizing diagnosis, staging, and management of gastrointestinal stromal tumors. J Am Coll Surg. 205(3):479-91 (Quiz 524), 2007
                                    8. Hong X et al: Gastrointestinal stromal tumor: role of CT in diagnosis and in response evaluation and surveillance after treatment with imatinib. Radiographics. 26(2):481-95, 2006
                                    9. Rubin BP: Gastrointestinal stromal tumours: an update. Histopathology. 48(1):83-96, 2006
                                    10. Warakaulle DR et al: MDCT appearance of gastrointestinal stromal tumors after therapy with imatinib mesylate. AJR Am J Roentgenol. 186(2):510-5, 2006
                                    11. King DM: The radiology of gastrointestinal stromal tumours (GIST). Cancer Imaging. 5:150-6, 2005
                                    12. Shankar S et al: Gastrointestinal stromal tumor: new nodule-within-a-mass pattern of recurrence after partial response to imatinib mesylate. Radiology. 235(3):892-8, 2005
                                    13. Burkill GJ et al: Malignant gastrointestinal stromal tumor: distribution, imaging features, and pattern of metastatic spread. Radiology. 226(2):527-32, 2003
                                    14. Levy AD et al: Gastrointestinal stromal tumors: radiologic features with pathologic correlation. Radiographics. 23(2):283-304, 456; quiz 532, 2003
                                    15. Sandberg AA et al: Updates on the cytogenetics and molecular genetics of bone and soft tissue tumors. gastrointestinal stromal tumors. Cancer Genet Cytogenet. 135(1):1-22, 2002
                                    16. DeMatteo RP et al: Two hundred gastrointestinal stromal tumors: recurrence patterns and prognostic factors for survival. Ann Surg. 231(1):51-8, 2000
                                    Related Anatomy
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                                    Related Differential Diagnoses
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                                    References
                                    Tables

                                    Tables

                                    Overview

                                    • General Comments

                                      • Classification

                                        Pathology

                                        • Routes Spread

                                          • General Features

                                            • Gross Pathology

                                              • Microscopic Features

                                                Imaging Findings

                                                • Detection

                                                  • Staging

                                                    • Restaging

                                                      Clinical Issues

                                                      • Presentation

                                                        • Cancer History

                                                          • Treatment Options

                                                            Reporting Checklist

                                                            • T Staging

                                                              • N Staging

                                                                • M Staging

                                                                  • Histologic Evaluation

                                                                    • Restaging

                                                                      Selected References

                                                                      1. American Joint Committee on Cancer: AJCC Cancer Staging Manual. 7th ed. New York: Springer. 175-80, 2010
                                                                      2. Agaimy A et al: Lymph node metastasis in gastrointestinal stromal tumours (GIST) occurs preferentially in young patients < or = 40 years: an overview based on our case material and the literature. Langenbecks Arch Surg. 394(2):375-81, 2009
                                                                      3. Wronski M et al: Gastrointestinal stromal tumors: ultrasonographic spectrum of the disease. J Ultrasound Med. 28(7):941-8, 2009
                                                                      4. Choi H: Response evaluation of gastrointestinal stromal tumors. Oncologist. 13 Suppl 2:4-7, 2008
                                                                      5. Badalamenti G et al: Gastrointestinal stromal tumors (GISTs): focus on histopathological diagnosis and biomolecular features. Ann Oncol. 18 Suppl 6:vi136-40, 2007
                                                                      6. Choi H et al: Correlation of computed tomography and positron emission tomography in patients with metastatic gastrointestinal stromal tumor treated at a single institution with imatinib mesylate: proposal of new computed tomography response criteria. J Clin Oncol. 25(13):1753-9, 2007
                                                                      7. Gutierrez JC et al: Optimizing diagnosis, staging, and management of gastrointestinal stromal tumors. J Am Coll Surg. 205(3):479-91 (Quiz 524), 2007
                                                                      8. Hong X et al: Gastrointestinal stromal tumor: role of CT in diagnosis and in response evaluation and surveillance after treatment with imatinib. Radiographics. 26(2):481-95, 2006
                                                                      9. Rubin BP: Gastrointestinal stromal tumours: an update. Histopathology. 48(1):83-96, 2006
                                                                      10. Warakaulle DR et al: MDCT appearance of gastrointestinal stromal tumors after therapy with imatinib mesylate. AJR Am J Roentgenol. 186(2):510-5, 2006
                                                                      11. King DM: The radiology of gastrointestinal stromal tumours (GIST). Cancer Imaging. 5:150-6, 2005
                                                                      12. Shankar S et al: Gastrointestinal stromal tumor: new nodule-within-a-mass pattern of recurrence after partial response to imatinib mesylate. Radiology. 235(3):892-8, 2005
                                                                      13. Burkill GJ et al: Malignant gastrointestinal stromal tumor: distribution, imaging features, and pattern of metastatic spread. Radiology. 226(2):527-32, 2003
                                                                      14. Levy AD et al: Gastrointestinal stromal tumors: radiologic features with pathologic correlation. Radiographics. 23(2):283-304, 456; quiz 532, 2003
                                                                      15. Sandberg AA et al: Updates on the cytogenetics and molecular genetics of bone and soft tissue tumors. gastrointestinal stromal tumors. Cancer Genet Cytogenet. 135(1):1-22, 2002
                                                                      16. DeMatteo RP et al: Two hundred gastrointestinal stromal tumors: recurrence patterns and prognostic factors for survival. Ann Surg. 231(1):51-8, 2000