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Staging: Multiple Myeloma
Chris Hanrahan, MD, PhD
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3

Overview

  • General Comments

    • Classification

      Pathology

      • Routes Spread

        • General Features

          • Gross Pathology

            • Microscopic Features

              Imaging Findings

              • Detection

                • Staging

                  Clinical Issues

                  • Presentation

                    • Cancer History

                      • Treatment Options

                        Reporting Checklist

                        • Radiographic Skeletal Survey (RSS)

                          • CT

                            • Whole-Body MR vs. Spine/Pelvis MR

                              • FDG PET/CT

                                • Imaging after Treatment

                                  Selected References

                                  1. Hanrahan CJ et al: Current concepts in the evaluation of multiple myeloma with MR imaging and FDG PET/CT. Radiographics. 30(1):127-42, 2010
                                  2. Dimopoulos M et al: International myeloma working group consensus statement and guidelines regarding the current role of imaging techniques in the diagnosis and monitoring of multiple myeloma. Leukemia. 23(9):1545-56, 2009
                                  3. Shortt CP et al: Whole-Body MRI versus PET in assessment of multiple myeloma disease activity. AJR Am J Roentgenol. 192(4):980-6, 2009
                                  4. Baur-Melnyk A et al: Whole-body MRI versus whole-body MDCT for staging of multiple myeloma. AJR Am J Roentgenol. 190(4):1097-104, 2008
                                  5. Kyle RA et al: Multiple myeloma. Blood. 111(6):2962-72, 2008
                                  6. Avet-Loiseau H et al: Genetic abnormalities and survival in multiple myeloma: the experience of the Intergroupe Francophone du Myélome. Blood. 109(8):3489-95, 2007
                                  7. Breyer RJ 3rd et al: Comparison of imaging with FDG PET/CT with other imaging modalities in myeloma. Skeletal Radiol. 35(9):632-40, 2006
                                  8. Durie BG: The role of anatomic and functional staging in myeloma: description of Durie/Salmon plus staging system. Eur J Cancer. 42(11):1539-43, 2006
                                  9. Greipp PR et al: International staging system for multiple myeloma. J Clin Oncol. 2005 May 20;23(15):3412-20. Epub 2005 Apr 4. Erratum in: J Clin Oncol. 23(25):6281, 2005
                                  10. Angtuaco EJ et al: Multiple myeloma: clinical review and diagnostic imaging. Radiology. 231(1):11-23, 2004
                                  Related Anatomy
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                                  Related Differential Diagnoses
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                                  References
                                  Tables

                                  Tables

                                  Overview

                                  • General Comments

                                    • Classification

                                      Pathology

                                      • Routes Spread

                                        • General Features

                                          • Gross Pathology

                                            • Microscopic Features

                                              Imaging Findings

                                              • Detection

                                                • Staging

                                                  Clinical Issues

                                                  • Presentation

                                                    • Cancer History

                                                      • Treatment Options

                                                        Reporting Checklist

                                                        • Radiographic Skeletal Survey (RSS)

                                                          • CT

                                                            • Whole-Body MR vs. Spine/Pelvis MR

                                                              • FDG PET/CT

                                                                • Imaging after Treatment

                                                                  Selected References

                                                                  1. Hanrahan CJ et al: Current concepts in the evaluation of multiple myeloma with MR imaging and FDG PET/CT. Radiographics. 30(1):127-42, 2010
                                                                  2. Dimopoulos M et al: International myeloma working group consensus statement and guidelines regarding the current role of imaging techniques in the diagnosis and monitoring of multiple myeloma. Leukemia. 23(9):1545-56, 2009
                                                                  3. Shortt CP et al: Whole-Body MRI versus PET in assessment of multiple myeloma disease activity. AJR Am J Roentgenol. 192(4):980-6, 2009
                                                                  4. Baur-Melnyk A et al: Whole-body MRI versus whole-body MDCT for staging of multiple myeloma. AJR Am J Roentgenol. 190(4):1097-104, 2008
                                                                  5. Kyle RA et al: Multiple myeloma. Blood. 111(6):2962-72, 2008
                                                                  6. Avet-Loiseau H et al: Genetic abnormalities and survival in multiple myeloma: the experience of the Intergroupe Francophone du Myélome. Blood. 109(8):3489-95, 2007
                                                                  7. Breyer RJ 3rd et al: Comparison of imaging with FDG PET/CT with other imaging modalities in myeloma. Skeletal Radiol. 35(9):632-40, 2006
                                                                  8. Durie BG: The role of anatomic and functional staging in myeloma: description of Durie/Salmon plus staging system. Eur J Cancer. 42(11):1539-43, 2006
                                                                  9. Greipp PR et al: International staging system for multiple myeloma. J Clin Oncol. 2005 May 20;23(15):3412-20. Epub 2005 Apr 4. Erratum in: J Clin Oncol. 23(25):6281, 2005
                                                                  10. Angtuaco EJ et al: Multiple myeloma: clinical review and diagnostic imaging. Radiology. 231(1):11-23, 2004