Struma ovarii is mature teratoma in which thyroid tissue is predominant or sole component
Benign thyroid tissue alone or constituting > 50% of dermoid cyst
Example of monodermal ovarian teratoma
IMAGING
General Features
CT Findings
MR Findings
Ultrasonographic Findings
Nuclear Medicine Findings
Imaging Recommendations
DIFFERENTIAL DIAGNOSIS
PATHOLOGY
General Features
Staging, Grading, & Classification
Gross Pathologic & Surgical Features
Microscopic Features
CLINICAL ISSUES
Presentation
Demographics
Natural History & Prognosis
Treatment
DIAGNOSTIC CHECKLIST
Consider
Image Interpretation Pearls
Selected References
Taylor EC et al: Multimodality imaging approach to ovarian neoplasms with pathologic correlation. Radiographics. 41(1):289-315, 2021
Dujardin MI et al: Struma ovarii: role of imaging? Insights Imaging. 5(1):41-51, 2014
Koo PJ et al: SPECT/CT of metastatic struma ovarii. Clin Nucl Med. 39(2):186-7, 2014
Shaaban AM et al: Ovarian malignant germ cell tumors: cellular classification and clinical and imaging features. Radiographics. 34(3):777-801, 2014
Nurliza Binti Md Nor et al: Three cases of struma ovarii underwent laparoscopic surgery with definite preoperative diagnosis. Acta Med Okayama. 67(3):191-5, 2013
Poncelet E et al: Value of dynamic contrast-enhanced MRI for tissue characterization of ovarian teratomas: correlation with histopathology. Clin Radiol. 68(9):909-16, 2013
Ikeuchi T et al: CT and MR features of struma ovarii. Abdom Imaging. 37(5):904-10, 2012
Khashper A et al: T2-hypointense adnexal lesions: an imaging algorithm. Radiographics. 32(4):1047-64, 2012
Shen J et al: Diagnosis of struma ovarii with medical imaging. Abdom Imaging. 36(5):627-31, 2011
Shanbhogue AK et al: Clinical syndromes associated with ovarian neoplasms: a comprehensive review. Radiographics. 30(4):903-19, 2010
Saba L et al: Mature and immature ovarian teratomas: CT, US and MR imaging characteristics. Eur J Radiol. 72(3):454-63, 2009
Jung SI et al: Struma ovarii: CT findings. Abdom Imaging. 33(6):740-3, 2008
Park SB et al: Imaging findings of complications and unusual manifestations of ovarian teratomas. Radiographics. 28(4):969-83, 2008
Savelli L et al: Imaging of gynecological disease (4): clinical and ultrasound characteristics of struma ovarii. Ultrasound Obstet Gynecol. 32(2):210-9, 2008
Yoo SC et al: Clinical characteristics of struma ovarii. J Gynecol Oncol. 19(2):135-8, 2008
McDougall IR: Metastatic struma ovarii: the burden of truth. Clin Nucl Med. 31(6):321-4, 2006
Cherng SC et al: Malignant struma ovarii with peritoneal implants and pelvic structures and liver metastases demonstrated by I-131 SPECT and low-dose CT. Clin Nucl Med. 30(12):797-8, 2005
Garcia A et al: Malignant struma ovarii mimic clear cell carcinoma. Arch Gynecol Obstet. 271(3):251-5, 2005
Ciccarelli A et al: Thyrotoxic adenoma followed by atypical hyperthyroidism due to struma ovarii: clinical and genetic studies. Eur J Endocrinol. 150(4):431-7, 2004
Utsunomiya D et al: Struma ovarii coexisting with mucinous cystadenoma detected by radioactive iodine. Clin Nucl Med. 28(9):725-7, 2003
Van de Moortele K et al: Struma ovarii: US and CT findings. JBR-BTR. 86(4):209-10, 2003
Huh JJ et al: Struma ovarii associated with pseudo-Meigs' syndrome and elevated serum CA 125. Gynecol Oncol. 86(2):231-4, 2002
Robboy SJ et al: Pathology of the Female Genital Tract. 1st ed. Harcourt. 672-4, 2002
Outwater EK et al: Ovarian teratomas: tumor types and imaging characteristics. Radiographics. 21(2):475-90, 2001
Emoto M et al: Transvaginal color Doppler ultrasonic characterization of benign and malignant ovarian cystic teratomas and comparison with serum squamous cell carcinoma antigen. Cancer. 88(10):2298-304, 2000
Kim JC et al: MR findings of struma ovarii. Clin Imaging. 24(1):28-33, 2000
Matsuki M et al: Struma ovarii: MRI findings. Br J Radiol. 73(865):87-90, 2000
Okada S et al: Cystic struma ovarii: imaging findings. J Comput Assist Tomogr. 24(3):413-5, 2000
Zalel Y et al: Sonographic and clinical characteristics of struma ovarii. J Ultrasound Med. 19(12):857-61, 2000
Joja I et al: I-123 uptake in nonfunctional struma ovarii. Clin Nucl Med. 23(1):10-2, 1998
Joja I et al: Struma ovarii: appearance on MR images. Abdom Imaging. 23(6):652-6, 1998
Dohke M et al: Struma ovarii: MR findings. J Comput Assist Tomogr. 21(2):265-7, 1997
Yamashita Y et al: Struma ovarii: MR appearances. Abdom Imaging. 22(1):100-2, 1997
Zalel Y et al: Doppler flow characteristics of dermoid cysts: unique appearance of struma ovarii. J Ultrasound Med. 16(5):355-8, 1997
Brenner W et al: Radiotherapy with iodine-131 in recurrent malignant struma ovarii. Eur J Nucl Med. 23(1):91-4, 1996
Matsumoto F et al: Struma ovarii: CT and MR findings. J Comput Assist Tomogr. 14(2):310-2, 1990
Related Anatomy
Loading...
Related Differential Diagnoses
Loading...
References
Tables
Tables
KEY FACTS
Terminology
Imaging
Top Differential Diagnoses
Clinical Issues
TERMINOLOGY
Definitions
Struma ovarii is mature teratoma in which thyroid tissue is predominant or sole component
Benign thyroid tissue alone or constituting > 50% of dermoid cyst
Example of monodermal ovarian teratoma
IMAGING
General Features
CT Findings
MR Findings
Ultrasonographic Findings
Nuclear Medicine Findings
Imaging Recommendations
DIFFERENTIAL DIAGNOSIS
PATHOLOGY
General Features
Staging, Grading, & Classification
Gross Pathologic & Surgical Features
Microscopic Features
CLINICAL ISSUES
Presentation
Demographics
Natural History & Prognosis
Treatment
DIAGNOSTIC CHECKLIST
Consider
Image Interpretation Pearls
Selected References
Taylor EC et al: Multimodality imaging approach to ovarian neoplasms with pathologic correlation. Radiographics. 41(1):289-315, 2021
Dujardin MI et al: Struma ovarii: role of imaging? Insights Imaging. 5(1):41-51, 2014
Koo PJ et al: SPECT/CT of metastatic struma ovarii. Clin Nucl Med. 39(2):186-7, 2014
Shaaban AM et al: Ovarian malignant germ cell tumors: cellular classification and clinical and imaging features. Radiographics. 34(3):777-801, 2014
Nurliza Binti Md Nor et al: Three cases of struma ovarii underwent laparoscopic surgery with definite preoperative diagnosis. Acta Med Okayama. 67(3):191-5, 2013
Poncelet E et al: Value of dynamic contrast-enhanced MRI for tissue characterization of ovarian teratomas: correlation with histopathology. Clin Radiol. 68(9):909-16, 2013
Ikeuchi T et al: CT and MR features of struma ovarii. Abdom Imaging. 37(5):904-10, 2012
Khashper A et al: T2-hypointense adnexal lesions: an imaging algorithm. Radiographics. 32(4):1047-64, 2012
Shen J et al: Diagnosis of struma ovarii with medical imaging. Abdom Imaging. 36(5):627-31, 2011
Shanbhogue AK et al: Clinical syndromes associated with ovarian neoplasms: a comprehensive review. Radiographics. 30(4):903-19, 2010
Saba L et al: Mature and immature ovarian teratomas: CT, US and MR imaging characteristics. Eur J Radiol. 72(3):454-63, 2009
Jung SI et al: Struma ovarii: CT findings. Abdom Imaging. 33(6):740-3, 2008
Park SB et al: Imaging findings of complications and unusual manifestations of ovarian teratomas. Radiographics. 28(4):969-83, 2008
Savelli L et al: Imaging of gynecological disease (4): clinical and ultrasound characteristics of struma ovarii. Ultrasound Obstet Gynecol. 32(2):210-9, 2008
Yoo SC et al: Clinical characteristics of struma ovarii. J Gynecol Oncol. 19(2):135-8, 2008
McDougall IR: Metastatic struma ovarii: the burden of truth. Clin Nucl Med. 31(6):321-4, 2006
Cherng SC et al: Malignant struma ovarii with peritoneal implants and pelvic structures and liver metastases demonstrated by I-131 SPECT and low-dose CT. Clin Nucl Med. 30(12):797-8, 2005
Garcia A et al: Malignant struma ovarii mimic clear cell carcinoma. Arch Gynecol Obstet. 271(3):251-5, 2005
Ciccarelli A et al: Thyrotoxic adenoma followed by atypical hyperthyroidism due to struma ovarii: clinical and genetic studies. Eur J Endocrinol. 150(4):431-7, 2004
Utsunomiya D et al: Struma ovarii coexisting with mucinous cystadenoma detected by radioactive iodine. Clin Nucl Med. 28(9):725-7, 2003
Van de Moortele K et al: Struma ovarii: US and CT findings. JBR-BTR. 86(4):209-10, 2003
Huh JJ et al: Struma ovarii associated with pseudo-Meigs' syndrome and elevated serum CA 125. Gynecol Oncol. 86(2):231-4, 2002
Robboy SJ et al: Pathology of the Female Genital Tract. 1st ed. Harcourt. 672-4, 2002
Outwater EK et al: Ovarian teratomas: tumor types and imaging characteristics. Radiographics. 21(2):475-90, 2001
Emoto M et al: Transvaginal color Doppler ultrasonic characterization of benign and malignant ovarian cystic teratomas and comparison with serum squamous cell carcinoma antigen. Cancer. 88(10):2298-304, 2000
Kim JC et al: MR findings of struma ovarii. Clin Imaging. 24(1):28-33, 2000
Matsuki M et al: Struma ovarii: MRI findings. Br J Radiol. 73(865):87-90, 2000
Okada S et al: Cystic struma ovarii: imaging findings. J Comput Assist Tomogr. 24(3):413-5, 2000
Zalel Y et al: Sonographic and clinical characteristics of struma ovarii. J Ultrasound Med. 19(12):857-61, 2000
Joja I et al: I-123 uptake in nonfunctional struma ovarii. Clin Nucl Med. 23(1):10-2, 1998
Joja I et al: Struma ovarii: appearance on MR images. Abdom Imaging. 23(6):652-6, 1998
Dohke M et al: Struma ovarii: MR findings. J Comput Assist Tomogr. 21(2):265-7, 1997
Yamashita Y et al: Struma ovarii: MR appearances. Abdom Imaging. 22(1):100-2, 1997
Zalel Y et al: Doppler flow characteristics of dermoid cysts: unique appearance of struma ovarii. J Ultrasound Med. 16(5):355-8, 1997
Brenner W et al: Radiotherapy with iodine-131 in recurrent malignant struma ovarii. Eur J Nucl Med. 23(1):91-4, 1996
Matsumoto F et al: Struma ovarii: CT and MR findings. J Comput Assist Tomogr. 14(2):310-2, 1990
STATdx includes over 200,000 searchable images, including x-ray, CT, MR, and ultrasound images. To access all images, please log in or subscribe.