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Sublingual Gland Carcinoma
Bronwyn E. Hamilton, MD
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KEY FACTS

  • Terminology

    • Imaging

      • Top Differential Diagnoses

        • Pathology

          • Clinical Issues

            • Diagnostic Checklist

              TERMINOLOGY

              • Abbreviations

                • Sublingual gland (SLG) carcinoma
                • Adenoid cystic carcinoma (ACCa)
                • Mucoepidermoid carcinoma (MECa)
              • Definitions

                • Primary salivary malignancy in SLG
                  • ACCa > MECa > others

              IMAGING

              • General Features

                • CT Findings

                  • MR Findings

                    • Nuclear Medicine Findings

                      • Imaging Recommendations

                        DIFFERENTIAL DIAGNOSIS

                          PATHOLOGY

                          • General Features

                            • Staging, Grading, & Classification

                              • Gross Pathologic & Surgical Features

                                • Microscopic Features

                                  CLINICAL ISSUES

                                  • Presentation

                                    • Demographics

                                      • Natural History & Prognosis

                                        • Treatment

                                          DIAGNOSTIC CHECKLIST

                                          • Consider

                                            • Image Interpretation Pearls

                                              • Reporting Tips

                                                Selected References

                                                1. Ryu IS et al: Clinical outcomes of patients with salivary gland carcinomas preoperatively misdiagnosed as benign lesions. Head Neck. 35(12):1764-70, 2013
                                                2. Sun G et al: The treatment of sublingual gland tumours. Int J Oral Maxillofac Surg. 39(9):863-8, 2010
                                                3. Saito M et al: Adenoid cystic carcinoma of sublingual gland involving the submandibular duct. Dentomaxillofac Radiol. 37(7):421-4, 2008
                                                4. Yu T et al: Malignant sublingual gland tumors: a retrospective clinicopathologic study of 28 cases. Oncology. 72(1-2):39-44, 2007
                                                5. Ogawa Y et al: Adenoid cystic carcinoma associated with salivary duct cyst in the sublingual gland. J Oral Pathol Med. 33(5):311-3, 2004
                                                6. Rinaldo A et al: Management of malignant sublingual salivary gland tumors. Oral Oncol. 40(1):2-5, 2004
                                                7. Asaumi J et al: Assessment of carcinoma in the sublingual region based on magnetic resonance imaging. Oncol Rep. 9(6):1283-7, 2002
                                                8. Schindler S et al: Diagnostic challenges in aspiration cytology of the salivary glands. Semin Diagn Pathol. 18(2):124-46, 2001
                                                9. Murakami R et al: MR imaging of squamous cell carcinoma of the floor of the mouth. Appearance of the sublingual and submandibular glands. Acta Radiol. 40(3):276-81, 1999
                                                10. McFall MR et al: Adenoid cystic carcinoma of the sublingual salivary gland in a 16-year-old female--report of a case and review of the literature. J Laryngol Otol. 111(5):485-8, 1997
                                                11. Spiro RH: Treating tumors of the sublingual glands, including a useful technique for repair of the floor of the mouth after resection. Am J Surg. 170(5):457-60, 1995
                                                12. Whear NM et al: Adenoid cystic carcinoma of the sublingual gland--an unusual presentation. Br J Oral Maxillofac Surg. 31(2):113-6, 1993
                                                13. Andersen LJ et al: Malignant epithelial tumors in the minor salivary glands, the submandibular gland, and the sublingual gland. Prognostic factors and treatment results. Cancer. 68(11):2431-7, 1991
                                                14. Batsakis JG: Sublingual gland. Ann Otol Rhinol Laryngol. 100(6):521-2, 1991
                                                15. Yu GY et al: Carcinoma of the salivary gland: a clinicopathologic study of 405 cases. Semin Surg Oncol. 3(4):240-4, 1987
                                                Related Anatomy
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                                                Related Differential Diagnoses
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                                                References
                                                Tables

                                                Tables

                                                KEY FACTS

                                                • Terminology

                                                  • Imaging

                                                    • Top Differential Diagnoses

                                                      • Pathology

                                                        • Clinical Issues

                                                          • Diagnostic Checklist

                                                            TERMINOLOGY

                                                            • Abbreviations

                                                              • Sublingual gland (SLG) carcinoma
                                                              • Adenoid cystic carcinoma (ACCa)
                                                              • Mucoepidermoid carcinoma (MECa)
                                                            • Definitions

                                                              • Primary salivary malignancy in SLG
                                                                • ACCa > MECa > others

                                                            IMAGING

                                                            • General Features

                                                              • CT Findings

                                                                • MR Findings

                                                                  • Nuclear Medicine Findings

                                                                    • Imaging Recommendations

                                                                      DIFFERENTIAL DIAGNOSIS

                                                                        PATHOLOGY

                                                                        • General Features

                                                                          • Staging, Grading, & Classification

                                                                            • Gross Pathologic & Surgical Features

                                                                              • Microscopic Features

                                                                                CLINICAL ISSUES

                                                                                • Presentation

                                                                                  • Demographics

                                                                                    • Natural History & Prognosis

                                                                                      • Treatment

                                                                                        DIAGNOSTIC CHECKLIST

                                                                                        • Consider

                                                                                          • Image Interpretation Pearls

                                                                                            • Reporting Tips

                                                                                              Selected References

                                                                                              1. Ryu IS et al: Clinical outcomes of patients with salivary gland carcinomas preoperatively misdiagnosed as benign lesions. Head Neck. 35(12):1764-70, 2013
                                                                                              2. Sun G et al: The treatment of sublingual gland tumours. Int J Oral Maxillofac Surg. 39(9):863-8, 2010
                                                                                              3. Saito M et al: Adenoid cystic carcinoma of sublingual gland involving the submandibular duct. Dentomaxillofac Radiol. 37(7):421-4, 2008
                                                                                              4. Yu T et al: Malignant sublingual gland tumors: a retrospective clinicopathologic study of 28 cases. Oncology. 72(1-2):39-44, 2007
                                                                                              5. Ogawa Y et al: Adenoid cystic carcinoma associated with salivary duct cyst in the sublingual gland. J Oral Pathol Med. 33(5):311-3, 2004
                                                                                              6. Rinaldo A et al: Management of malignant sublingual salivary gland tumors. Oral Oncol. 40(1):2-5, 2004
                                                                                              7. Asaumi J et al: Assessment of carcinoma in the sublingual region based on magnetic resonance imaging. Oncol Rep. 9(6):1283-7, 2002
                                                                                              8. Schindler S et al: Diagnostic challenges in aspiration cytology of the salivary glands. Semin Diagn Pathol. 18(2):124-46, 2001
                                                                                              9. Murakami R et al: MR imaging of squamous cell carcinoma of the floor of the mouth. Appearance of the sublingual and submandibular glands. Acta Radiol. 40(3):276-81, 1999
                                                                                              10. McFall MR et al: Adenoid cystic carcinoma of the sublingual salivary gland in a 16-year-old female--report of a case and review of the literature. J Laryngol Otol. 111(5):485-8, 1997
                                                                                              11. Spiro RH: Treating tumors of the sublingual glands, including a useful technique for repair of the floor of the mouth after resection. Am J Surg. 170(5):457-60, 1995
                                                                                              12. Whear NM et al: Adenoid cystic carcinoma of the sublingual gland--an unusual presentation. Br J Oral Maxillofac Surg. 31(2):113-6, 1993
                                                                                              13. Andersen LJ et al: Malignant epithelial tumors in the minor salivary glands, the submandibular gland, and the sublingual gland. Prognostic factors and treatment results. Cancer. 68(11):2431-7, 1991
                                                                                              14. Batsakis JG: Sublingual gland. Ann Otol Rhinol Laryngol. 100(6):521-2, 1991
                                                                                              15. Yu GY et al: Carcinoma of the salivary gland: a clinicopathologic study of 405 cases. Semin Surg Oncol. 3(4):240-4, 1987