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KEY FACTS
Terminology
Imaging
Top Differential Diagnoses
Pathology
Clinical Issues
Diagnostic Checklist
TERMINOLOGY
Abbreviations
- Submandibular space (SMS) nodal non-Hodgkin lymphoma (NHL)
Definitions
- NHL: Lymphoreticular system malignancy, postulated to arise from lymphocytes & derivatives
- H&N NHL has 3 main forms: Nodal, nonnodal lymphatic (Waldeyer ring), & nonnodal extralymphatic (e.g., thyroid, lacrimal)
IMAGING
General Features
CT Findings
MR Findings
Ultrasonographic Findings
Nuclear Medicine Findings
Imaging Recommendations
DIFFERENTIAL DIAGNOSIS
PATHOLOGY
General Features
Staging, Grading, & Classification
Gross Pathologic & Surgical Features
Microscopic Features
CLINICAL ISSUES
Presentation
Demographics
Natural History & Prognosis
Treatment
DIAGNOSTIC CHECKLIST
Consider
Image Interpretation Pearls
Selected References
- Ma L et al: Extranodal natural killer/T cell lymphoma with involvement of the bilateral submandibular lymph node mimicking a rhinoscleroma: a diagnostic challenge. J Stomatol Oral Maxillofac Surg. 122(1):107-11, 2021
- McCarten KM et al: Imaging for diagnosis, staging and response assessment of Hodgkin lymphoma and non-Hodgkin lymphoma. Pediatr Radiol. 49(11):1545-64, 2019
- Flechsig P et al: Role of CT density in PET/CT-based assessment of lymphoma. Mol Imaging Biol. 20(4):641-9, 2018
- Patel S et al: Imaging of the sublingual and submandibular spaces. Insights Imaging. 9(3):391-401, 2018
- Jaffe ES et al: Understanding the new WHO Classification of lymphoid malignancies: why it's important and how it will affect practice. Am Soc Clin Oncol Educ Book. 37:535-46, 2017
- Silva TD et al: Oral manifestations of lymphoma: a systematic review. Ecancermedicalscience. 10:665, 2016
- Houldcroft CJ et al: Host genetics of Epstein-Barr virus infection, latency and disease. Rev Med Virol. 25(2):71-84, 2015
- Fueger BJ et al: Comparison of CT, PET, and PET/CT for staging of patients with indolent non-Hodgkin's lymphoma. Mol Imaging Biol. 11(4):269-74, 2009
- Mahmood NS et al: Multiple 'lumps' and 'bumps' in the head with bilateral proptosis: a unique presentation of systemic non-Hodgkin's lymphoma. Pediatr Neurosurg. 45(6):481-2, 2009
- Taylor CR: The WHO classification of lymphomas: cost-effective immunohistochemistry using a deductive reasoning "decision tree" approach: part II: the decision tree approach: diffuse patterns of proliferation in lymph nodes. Appl Immunohistochem Mol Morphol. 17(6):470-82, 2009
- Urquhart A et al: Hodgkin's and non-Hodgkin's lymphoma of the head and neck. Laryngoscope. 111(9):1565-9, 2001
- Nathu RM et al: Non-Hodgkin's lymphoma of the head and neck: a 30-year experience at the University of Florida. Head Neck. 21(3):247-54, 1999
- Harnsberger HR et al: Non-Hodgkin's lymphoma of the head and neck: CT evaluation of nodal and extranodal sites. AJR Am J Roentgenol. 149(4):785-91, 1987
- Lee YY et al: Lymphomas of the head and neck: CT findings at initial presentation. AJR Am J Roentgenol. 149(3):575-81, 1987
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References
Tables
Tables
KEY FACTS
Terminology
Imaging
Top Differential Diagnoses
Pathology
Clinical Issues
Diagnostic Checklist
TERMINOLOGY
Abbreviations
- Submandibular space (SMS) nodal non-Hodgkin lymphoma (NHL)
Definitions
- NHL: Lymphoreticular system malignancy, postulated to arise from lymphocytes & derivatives
- H&N NHL has 3 main forms: Nodal, nonnodal lymphatic (Waldeyer ring), & nonnodal extralymphatic (e.g., thyroid, lacrimal)
IMAGING
General Features
CT Findings
MR Findings
Ultrasonographic Findings
Nuclear Medicine Findings
Imaging Recommendations
DIFFERENTIAL DIAGNOSIS
PATHOLOGY
General Features
Staging, Grading, & Classification
Gross Pathologic & Surgical Features
Microscopic Features
CLINICAL ISSUES
Presentation
Demographics
Natural History & Prognosis
Treatment
DIAGNOSTIC CHECKLIST
Consider
Image Interpretation Pearls
Selected References
- Ma L et al: Extranodal natural killer/T cell lymphoma with involvement of the bilateral submandibular lymph node mimicking a rhinoscleroma: a diagnostic challenge. J Stomatol Oral Maxillofac Surg. 122(1):107-11, 2021
- McCarten KM et al: Imaging for diagnosis, staging and response assessment of Hodgkin lymphoma and non-Hodgkin lymphoma. Pediatr Radiol. 49(11):1545-64, 2019
- Flechsig P et al: Role of CT density in PET/CT-based assessment of lymphoma. Mol Imaging Biol. 20(4):641-9, 2018
- Patel S et al: Imaging of the sublingual and submandibular spaces. Insights Imaging. 9(3):391-401, 2018
- Jaffe ES et al: Understanding the new WHO Classification of lymphoid malignancies: why it's important and how it will affect practice. Am Soc Clin Oncol Educ Book. 37:535-46, 2017
- Silva TD et al: Oral manifestations of lymphoma: a systematic review. Ecancermedicalscience. 10:665, 2016
- Houldcroft CJ et al: Host genetics of Epstein-Barr virus infection, latency and disease. Rev Med Virol. 25(2):71-84, 2015
- Fueger BJ et al: Comparison of CT, PET, and PET/CT for staging of patients with indolent non-Hodgkin's lymphoma. Mol Imaging Biol. 11(4):269-74, 2009
- Mahmood NS et al: Multiple 'lumps' and 'bumps' in the head with bilateral proptosis: a unique presentation of systemic non-Hodgkin's lymphoma. Pediatr Neurosurg. 45(6):481-2, 2009
- Taylor CR: The WHO classification of lymphomas: cost-effective immunohistochemistry using a deductive reasoning "decision tree" approach: part II: the decision tree approach: diffuse patterns of proliferation in lymph nodes. Appl Immunohistochem Mol Morphol. 17(6):470-82, 2009
- Urquhart A et al: Hodgkin's and non-Hodgkin's lymphoma of the head and neck. Laryngoscope. 111(9):1565-9, 2001
- Nathu RM et al: Non-Hodgkin's lymphoma of the head and neck: a 30-year experience at the University of Florida. Head Neck. 21(3):247-54, 1999
- Harnsberger HR et al: Non-Hodgkin's lymphoma of the head and neck: CT evaluation of nodal and extranodal sites. AJR Am J Roentgenol. 149(4):785-91, 1987
- Lee YY et al: Lymphomas of the head and neck: CT findings at initial presentation. AJR Am J Roentgenol. 149(3):575-81, 1987
