Benign or malignant neoplasm extending to superior thoracic inlet with severe shoulder/arm pain along C8, T1, T2 nerve trunks, Horner syndrome, weakness + atrophy of intrinsic hand muscles (Pancoast syndrome)
Non-small cell lung carcinoma (NSCLC) most frequent etiology
IMAGING
General Features
Radiographic Findings
CT Findings
MR Findings
Angiographic Findings
Nonvascular Interventions
Nuclear Medicine Findings
Imaging Recommendations
DIFFERENTIAL DIAGNOSIS
PATHOLOGY
General Features
Staging, Grading, & Classification
Gross Pathologic & Surgical Features
Microscopic Features
CLINICAL ISSUES
Presentation
Demographics
Natural History & Prognosis
Treatment
DIAGNOSTIC CHECKLIST
Consider
Selected References
Palumbo VD et al: Pancoast tumour: current therapeutic options. Clin Ter. 170(4):e291-4, 2019
Solli P et al: Surgical treatment of superior sulcus tumors: a 15-year single-center experience. Semin Thorac Cardiovasc Surg. 29(1):79-88, 2017
Nikolaos P et al: Therapeutic modalities for Pancoast tumors. J Thorac Dis. 6(Suppl 1):S180-93, 2014
Foroulis CN et al: Superior sulcus (Pancoast) tumors: current evidence on diagnosis and radical treatment. J Thorac Dis. 5(Suppl 4):S342-58, 2013
Manenti G et al: Pancoast tumor: the role of magnetic resonance imaging. Case Rep Radiol. 2013:479120, 2013
Younga J et al: Venous hemangioma presenting as a superior sulcus tumor. Ann Thorac Surg. 90(6):2033-5, 2010
Tamura M et al: Current treatment paradigms of superior sulcus tumours. Eur J Cardiothorac Surg. 36(4):747-53, 2009
Davis GA et al: Pancoast tumors. Neurosurg Clin N Am. 19(4):545-57, v-vi, 2008
Davis GA et al: Pancoast tumor resection with preservation of brachial plexus and hand function. Neurosurg Focus. 22(6):E15, 2007
Rusch VW: Management of Pancoast tumours. Lancet Oncol. 7(12):997-1005, 2006
Shah H et al: Brain: the common site of relapse in patients with Pancoast or superior sulcus tumors. J Thorac Oncol. 1(9):1020-2, 2006
Archie VC et al: Superior sulcus tumors: a mini-review. Oncologist. 9(5):550-5, 2004
Huehnergarth KV et al: Superior pulmonary sulcus tumor with Pancoast syndrome. Mayo Clin Proc. 79(10):1268, 2004
Weyant MJ et al: Imaging of pleural and chest wall tumors. Thorac Surg Clin. 14(1):15-23, 2004
Beshay M et al: Tuberculosis presenting as Pancoast tumor. Ann Thorac Surg. 76(5):1733-5, 2003
Detterbeck FC et al: Lung cancer. Special treatment issues. Chest. 123(1 Suppl):244S-58S, 2003
Detterbeck FC: Changes in the treatment of Pancoast tumors. Ann Thorac Surg. 75(6):1990-7, 2003
Kichari JR et al: MR imaging of the brachial plexus: current imaging sequences, normal findings, and findings in a spectrum of focal lesions with MR-pathologic correlation. Curr Probl Diagn Radiol. 32(2):88-101, 2003
Dartevelle P et al: Surgical management of superior sulcus tumors. Oncologist. 4(5):398-407, 1999
Ducic Y et al: A logical approach to the thoracic inlet: the Dartevelle approach revisited. Head Neck. 21(8):767-71, 1999
Jones DR et al: Pancoast tumors of the lung. Curr Opin Pulm Med. 4(4):191-7, 1998
Kuhlman JE et al: CT and MR imaging evaluation of chest wall disorders. Radiographics. 14(3):571-95, 1994
Related Anatomy
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Related Differential Diagnoses
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References
Tables
Tables
KEY FACTS
Terminology
Imaging
Top Differential Diagnoses
Pathology
Clinical Issues
Diagnostic Checklist
TERMINOLOGY
Synonyms
Pancoast tumor
Definitions
Benign or malignant neoplasm extending to superior thoracic inlet with severe shoulder/arm pain along C8, T1, T2 nerve trunks, Horner syndrome, weakness + atrophy of intrinsic hand muscles (Pancoast syndrome)
Non-small cell lung carcinoma (NSCLC) most frequent etiology
IMAGING
General Features
Radiographic Findings
CT Findings
MR Findings
Angiographic Findings
Nonvascular Interventions
Nuclear Medicine Findings
Imaging Recommendations
DIFFERENTIAL DIAGNOSIS
PATHOLOGY
General Features
Staging, Grading, & Classification
Gross Pathologic & Surgical Features
Microscopic Features
CLINICAL ISSUES
Presentation
Demographics
Natural History & Prognosis
Treatment
DIAGNOSTIC CHECKLIST
Consider
Selected References
Palumbo VD et al: Pancoast tumour: current therapeutic options. Clin Ter. 170(4):e291-4, 2019
Solli P et al: Surgical treatment of superior sulcus tumors: a 15-year single-center experience. Semin Thorac Cardiovasc Surg. 29(1):79-88, 2017
Nikolaos P et al: Therapeutic modalities for Pancoast tumors. J Thorac Dis. 6(Suppl 1):S180-93, 2014
Foroulis CN et al: Superior sulcus (Pancoast) tumors: current evidence on diagnosis and radical treatment. J Thorac Dis. 5(Suppl 4):S342-58, 2013
Manenti G et al: Pancoast tumor: the role of magnetic resonance imaging. Case Rep Radiol. 2013:479120, 2013
Younga J et al: Venous hemangioma presenting as a superior sulcus tumor. Ann Thorac Surg. 90(6):2033-5, 2010
Tamura M et al: Current treatment paradigms of superior sulcus tumours. Eur J Cardiothorac Surg. 36(4):747-53, 2009
Davis GA et al: Pancoast tumors. Neurosurg Clin N Am. 19(4):545-57, v-vi, 2008
Davis GA et al: Pancoast tumor resection with preservation of brachial plexus and hand function. Neurosurg Focus. 22(6):E15, 2007
Rusch VW: Management of Pancoast tumours. Lancet Oncol. 7(12):997-1005, 2006
Shah H et al: Brain: the common site of relapse in patients with Pancoast or superior sulcus tumors. J Thorac Oncol. 1(9):1020-2, 2006
Archie VC et al: Superior sulcus tumors: a mini-review. Oncologist. 9(5):550-5, 2004
Huehnergarth KV et al: Superior pulmonary sulcus tumor with Pancoast syndrome. Mayo Clin Proc. 79(10):1268, 2004
Weyant MJ et al: Imaging of pleural and chest wall tumors. Thorac Surg Clin. 14(1):15-23, 2004
Beshay M et al: Tuberculosis presenting as Pancoast tumor. Ann Thorac Surg. 76(5):1733-5, 2003
Detterbeck FC et al: Lung cancer. Special treatment issues. Chest. 123(1 Suppl):244S-58S, 2003
Detterbeck FC: Changes in the treatment of Pancoast tumors. Ann Thorac Surg. 75(6):1990-7, 2003
Kichari JR et al: MR imaging of the brachial plexus: current imaging sequences, normal findings, and findings in a spectrum of focal lesions with MR-pathologic correlation. Curr Probl Diagn Radiol. 32(2):88-101, 2003
Dartevelle P et al: Surgical management of superior sulcus tumors. Oncologist. 4(5):398-407, 1999
Ducic Y et al: A logical approach to the thoracic inlet: the Dartevelle approach revisited. Head Neck. 21(8):767-71, 1999
Jones DR et al: Pancoast tumors of the lung. Curr Opin Pulm Med. 4(4):191-7, 1998
Kuhlman JE et al: CT and MR imaging evaluation of chest wall disorders. Radiographics. 14(3):571-95, 1994
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