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Head and Neck
Diagnosis
Hypopharynx, Larynx, and Cervical Trachea
Infectious and Inflammatory Lesions
Supraglottitis
Supraglottitis
Troy A. Hutchins, MD; Joshua E. Lantos, MD
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KEY FACTS

  • Terminology

    • Imaging

      • Top Differential Diagnoses

        • Pathology

          • Clinical Issues

            • Diagnostic Checklist

              TERMINOLOGY

              • Synonyms

                • Adult epiglottitis

              • Definitions

                • Relatively uncommon, potentially life-threatening infection/inflammation of supraglottic larynx in adult with sore throat & dysphagia

              IMAGING

              • General Features

                • Imaging Recommendations

                  • Radiographic Findings

                    • CT Findings

                      DIFFERENTIAL DIAGNOSIS

                        PATHOLOGY

                        • General Features

                          CLINICAL ISSUES

                          • Presentation

                            • Demographics

                              • Natural History & Prognosis

                                • Treatment

                                  DIAGNOSTIC CHECKLIST

                                  • Consider

                                    • Image Interpretation Pearls

                                      • Reporting Tips

                                        Selected References

                                        1. Bozzella MJ et al: Epiglottitis associated with intermittent E-cigarette use: the vagaries of vaping toxicity. Pediatrics. 145(3), 2020
                                        2. Ringel B et al: Low rates of airway intervention in adult supraglottitis: a case series and meta-analysis. Am J Otolaryngol. 41(4):102482, 2020
                                        3. Sideris A et al: A systematic review and meta-analysis of predictors of airway intervention in adult epiglottitis. Laryngoscope. 130(2):465-73, 2020
                                        4. Chroboczek T et al: Long-term outcome of critically ill adult patients with acute epiglottitis. PLoS One. 10(5):e0125736, 2015
                                        5. Fujiwara T et al: Diagnostic accuracy of lateral neck radiography in ruling out supraglottitis: a prospective observational study. Emerg Med J. 32(5):348-52, 2015
                                        6. Lotfizadeh A et al: Viral supraglottitis in an adult. Ear Nose Throat J. 88(2):768-70, 2009
                                        7. Vigil KJ et al: Severe parainfluenza virus type 2 supraglottitis in an immunocompetent adult host: an unusual cause of a paramyxoviridae viral infection. J Intern Med. 265(3):397-400, 2009
                                        8. Glynn F et al: Diagnosis and management of supraglottitis (epiglottitis). Curr Infect Dis Rep. 10(3):200-4, 2008
                                        9. Haidary A et al: Unsuspected swallowing of a partial denture. AJNR Am J Neuroradiol. 28(9):1734-5, 2007
                                        10. Kortepeter MG et al: Fulminant supraglottitis from Neisseria meningitidis. Emerg Infect Dis. 13(3):502-4, 2007
                                        11. Hafidh MA et al: Acute epiglottitis in adults: a recent experience with 10 cases. J Laryngol Otol. 120(4):310-3, 2006
                                        12. Deutsch ES: Traumatic supraglottitis. Int J Pediatr Otorhinolaryngol. 68(6):851-4, 2004
                                        13. Madhotra D et al: Airway intervention in adult supraglottitis. Ir J Med Sci. 173(4):197-9, 2004
                                        14. Phillips JS et al: Corticosteroids for supraglottitis. Br J Anaesth. 92(3):454-5, 2004
                                        15. Shahzad A: Mediastinal compression secondary to supraglottitis: a case report. Am J Otolaryngol. 25(2):126-8, 2004
                                        16. Osborne R et al: Adult supraglottitis subsequent to smoking crack cocaine. Ear Nose Throat J. 82(1):53-5, 2003
                                        17. Deeb ZE: Acute supraglottitis in adults: early indicators of airway obstruction. Am J Otolaryngol. 18(2):112-5, 1997
                                        18. Smith MM et al: CT in adult supraglottitis. AJNR Am J Neuroradiol. 17(7):1355-8, 1996
                                        19. Nemzek WR et al: A reappraisal of the radiologic findings of acute inflammation of the epiglottis and supraglottic structures in adults. AJNR Am J Neuroradiol. 16(3):495-502, 1995
                                        20. Dort JC et al: Acute epiglottitis in adults: diagnosis and treatment in 43 patients. J Otolaryngol. 23(4):281-5, 1994
                                        21. Barrow HN et al: Adult supraglottitis. Otolaryngol Head Neck Surg. 109(3 Pt 1):474-7, 1993
                                        Related Anatomy
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                                        Related Differential Diagnoses
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                                        References
                                        Tables

                                        Tables

                                        KEY FACTS

                                        • Terminology

                                          • Imaging

                                            • Top Differential Diagnoses

                                              • Pathology

                                                • Clinical Issues

                                                  • Diagnostic Checklist

                                                    TERMINOLOGY

                                                    • Synonyms

                                                      • Adult epiglottitis

                                                    • Definitions

                                                      • Relatively uncommon, potentially life-threatening infection/inflammation of supraglottic larynx in adult with sore throat & dysphagia

                                                    IMAGING

                                                    • General Features

                                                      • Imaging Recommendations

                                                        • Radiographic Findings

                                                          • CT Findings

                                                            DIFFERENTIAL DIAGNOSIS

                                                              PATHOLOGY

                                                              • General Features

                                                                CLINICAL ISSUES

                                                                • Presentation

                                                                  • Demographics

                                                                    • Natural History & Prognosis

                                                                      • Treatment

                                                                        DIAGNOSTIC CHECKLIST

                                                                        • Consider

                                                                          • Image Interpretation Pearls

                                                                            • Reporting Tips

                                                                              Selected References

                                                                              1. Bozzella MJ et al: Epiglottitis associated with intermittent E-cigarette use: the vagaries of vaping toxicity. Pediatrics. 145(3), 2020
                                                                              2. Ringel B et al: Low rates of airway intervention in adult supraglottitis: a case series and meta-analysis. Am J Otolaryngol. 41(4):102482, 2020
                                                                              3. Sideris A et al: A systematic review and meta-analysis of predictors of airway intervention in adult epiglottitis. Laryngoscope. 130(2):465-73, 2020
                                                                              4. Chroboczek T et al: Long-term outcome of critically ill adult patients with acute epiglottitis. PLoS One. 10(5):e0125736, 2015
                                                                              5. Fujiwara T et al: Diagnostic accuracy of lateral neck radiography in ruling out supraglottitis: a prospective observational study. Emerg Med J. 32(5):348-52, 2015
                                                                              6. Lotfizadeh A et al: Viral supraglottitis in an adult. Ear Nose Throat J. 88(2):768-70, 2009
                                                                              7. Vigil KJ et al: Severe parainfluenza virus type 2 supraglottitis in an immunocompetent adult host: an unusual cause of a paramyxoviridae viral infection. J Intern Med. 265(3):397-400, 2009
                                                                              8. Glynn F et al: Diagnosis and management of supraglottitis (epiglottitis). Curr Infect Dis Rep. 10(3):200-4, 2008
                                                                              9. Haidary A et al: Unsuspected swallowing of a partial denture. AJNR Am J Neuroradiol. 28(9):1734-5, 2007
                                                                              10. Kortepeter MG et al: Fulminant supraglottitis from Neisseria meningitidis. Emerg Infect Dis. 13(3):502-4, 2007
                                                                              11. Hafidh MA et al: Acute epiglottitis in adults: a recent experience with 10 cases. J Laryngol Otol. 120(4):310-3, 2006
                                                                              12. Deutsch ES: Traumatic supraglottitis. Int J Pediatr Otorhinolaryngol. 68(6):851-4, 2004
                                                                              13. Madhotra D et al: Airway intervention in adult supraglottitis. Ir J Med Sci. 173(4):197-9, 2004
                                                                              14. Phillips JS et al: Corticosteroids for supraglottitis. Br J Anaesth. 92(3):454-5, 2004
                                                                              15. Shahzad A: Mediastinal compression secondary to supraglottitis: a case report. Am J Otolaryngol. 25(2):126-8, 2004
                                                                              16. Osborne R et al: Adult supraglottitis subsequent to smoking crack cocaine. Ear Nose Throat J. 82(1):53-5, 2003
                                                                              17. Deeb ZE: Acute supraglottitis in adults: early indicators of airway obstruction. Am J Otolaryngol. 18(2):112-5, 1997
                                                                              18. Smith MM et al: CT in adult supraglottitis. AJNR Am J Neuroradiol. 17(7):1355-8, 1996
                                                                              19. Nemzek WR et al: A reappraisal of the radiologic findings of acute inflammation of the epiglottis and supraglottic structures in adults. AJNR Am J Neuroradiol. 16(3):495-502, 1995
                                                                              20. Dort JC et al: Acute epiglottitis in adults: diagnosis and treatment in 43 patients. J Otolaryngol. 23(4):281-5, 1994
                                                                              21. Barrow HN et al: Adult supraglottitis. Otolaryngol Head Neck Surg. 109(3 Pt 1):474-7, 1993