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KEY FACTS
Terminology
Imaging
Top Differential Diagnoses
Pathology
Clinical Issues
Diagnostic Checklist
TERMINOLOGY
Abbreviations
- Swyer-James-MacLeod syndrome (SJM)
Synonyms
- Swyer-James syndrome
- MacLeod syndrome
- Controversy regarding eponyms to be ascribed to syndrome
- MacLeod presented report of 9 patients with "abnormal transradiancy of 1 lung," which was "small or normal size" at British Thoracic Society meeting in London in February of 1952
- Swyer and James published case of "unilateral pulmonary emphysema" in 1953
- MacLeod published his work in 1954
Definitions
- Constrictive bronchiolitis as result of childhood infectious bronchiolitis (typically from Adenovirus infection)
- Constrictive bronchiolitis: Irreversible obstructive small airways disease characterized by submucosal and peribronchiolar fibrosis with resultant destruction and obliterative scarring of small airways
- Mosaic attenuation (perfusion): Geographic regions of increased parenchymal attenuation with intrinsic large pulmonary vessels adjacent to regions of decreased attenuation with intrinsic small pulmonary vessels
IMAGING
General Features
Radiographic Findings
CT Findings
Nuclear Medicine Findings
Imaging Recommendations
DIFFERENTIAL DIAGNOSIS
PATHOLOGY
General Features
Staging, Grading, & Classification
Microscopic Features
CLINICAL ISSUES
Presentation
Demographics
Natural History & Prognosis
Treatment
DIAGNOSTIC CHECKLIST
Consider
Selected References
- Behrendt A et al: Swyer-James-MacLeod Syndrome 2020
- Gomes de Farias LP et al: Swyer-James-MacLeod syndrome: the hyperlucent lung. Radiol Cardiothorac Imaging. 2(3):e190246, 2020
- Griffiths P et al: Swyer-James-MacLeod syndrome and pulmonary arteriovenous malformations: a rare combination. BMJ Case Rep. 13(1), 2020
- Kawasuji H et al: Multimodal imaging findings in an adult case of Swyer-James-MacLeod syndrome. Respirol Case Rep. 5(4):e00236, 2017
- Winningham PJ et al: Bronchiolitis: a practical approach for the general radiologist. Radiographics. 37(3):777-94, 2017
- Chaucer B et al: Swyer-James-Macleod syndrome: a rare finding and important differential in the ED setting. Am J Emerg Med. 34(7):1329.e3-4, 2016
- Milanese G et al: Lung volume reduction of pulmonary emphysema: the radiologist task. Curr Opin Pulm Med. 22(2):179-86, 2016
- Yu J: Postinfectious bronchiolitis obliterans in children: lessons from bronchiolitis obliterans after lung transplantation and hematopoietic stem cell transplantation. Korean J Pediatr. 58(12):459-65, 2015
- Mosquera RA et al: Dysanaptic growth of lung and airway in children with post-infectious bronchiolitis obliterans. Clin Respir J. 8(1):63-71, 2014
- Xie BQ et al: Ventilation/perfusion scintigraphy in children with post-infectious bronchiolitis obliterans: a pilot study. PLoS One. 9(5):e98381, 2014
- Wasilewska E et al: Unilateral hyperlucent lung in children. AJR Am J Roentgenol. 198(5):W400-14, 2012
- Champs NS et al: Post-infectious bronchiolitis obliterans in children. J Pediatr (Rio J). 87(3):187-98, 2011
- Dillman JR et al: Expanding upon the unilateral hyperlucent hemithorax in children. Radiographics. 31(3):723-41, 2011
- Müller NL: Unilateral hyperlucent lung: MacLeod versus Swyer-James. Clin Radiol. 59(11):1048, 2004
- Lucaya J et al: Spectrum of manifestations of Swyer-James-MacLeod syndrome. J Comput Assist Tomogr. 22(4):592-7, 1998
Related Anatomy
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References
Tables
Tables
KEY FACTS
Terminology
Imaging
Top Differential Diagnoses
Pathology
Clinical Issues
Diagnostic Checklist
TERMINOLOGY
Abbreviations
- Swyer-James-MacLeod syndrome (SJM)
Synonyms
- Swyer-James syndrome
- MacLeod syndrome
- Controversy regarding eponyms to be ascribed to syndrome
- MacLeod presented report of 9 patients with "abnormal transradiancy of 1 lung," which was "small or normal size" at British Thoracic Society meeting in London in February of 1952
- Swyer and James published case of "unilateral pulmonary emphysema" in 1953
- MacLeod published his work in 1954
Definitions
- Constrictive bronchiolitis as result of childhood infectious bronchiolitis (typically from Adenovirus infection)
- Constrictive bronchiolitis: Irreversible obstructive small airways disease characterized by submucosal and peribronchiolar fibrosis with resultant destruction and obliterative scarring of small airways
- Mosaic attenuation (perfusion): Geographic regions of increased parenchymal attenuation with intrinsic large pulmonary vessels adjacent to regions of decreased attenuation with intrinsic small pulmonary vessels
IMAGING
General Features
Radiographic Findings
CT Findings
Nuclear Medicine Findings
Imaging Recommendations
DIFFERENTIAL DIAGNOSIS
PATHOLOGY
General Features
Staging, Grading, & Classification
Microscopic Features
CLINICAL ISSUES
Presentation
Demographics
Natural History & Prognosis
Treatment
DIAGNOSTIC CHECKLIST
Consider
Selected References
- Behrendt A et al: Swyer-James-MacLeod Syndrome 2020
- Gomes de Farias LP et al: Swyer-James-MacLeod syndrome: the hyperlucent lung. Radiol Cardiothorac Imaging. 2(3):e190246, 2020
- Griffiths P et al: Swyer-James-MacLeod syndrome and pulmonary arteriovenous malformations: a rare combination. BMJ Case Rep. 13(1), 2020
- Kawasuji H et al: Multimodal imaging findings in an adult case of Swyer-James-MacLeod syndrome. Respirol Case Rep. 5(4):e00236, 2017
- Winningham PJ et al: Bronchiolitis: a practical approach for the general radiologist. Radiographics. 37(3):777-94, 2017
- Chaucer B et al: Swyer-James-Macleod syndrome: a rare finding and important differential in the ED setting. Am J Emerg Med. 34(7):1329.e3-4, 2016
- Milanese G et al: Lung volume reduction of pulmonary emphysema: the radiologist task. Curr Opin Pulm Med. 22(2):179-86, 2016
- Yu J: Postinfectious bronchiolitis obliterans in children: lessons from bronchiolitis obliterans after lung transplantation and hematopoietic stem cell transplantation. Korean J Pediatr. 58(12):459-65, 2015
- Mosquera RA et al: Dysanaptic growth of lung and airway in children with post-infectious bronchiolitis obliterans. Clin Respir J. 8(1):63-71, 2014
- Xie BQ et al: Ventilation/perfusion scintigraphy in children with post-infectious bronchiolitis obliterans: a pilot study. PLoS One. 9(5):e98381, 2014
- Wasilewska E et al: Unilateral hyperlucent lung in children. AJR Am J Roentgenol. 198(5):W400-14, 2012
- Champs NS et al: Post-infectious bronchiolitis obliterans in children. J Pediatr (Rio J). 87(3):187-98, 2011
- Dillman JR et al: Expanding upon the unilateral hyperlucent hemithorax in children. Radiographics. 31(3):723-41, 2011
- Müller NL: Unilateral hyperlucent lung: MacLeod versus Swyer-James. Clin Radiol. 59(11):1048, 2004
- Lucaya J et al: Spectrum of manifestations of Swyer-James-MacLeod syndrome. J Comput Assist Tomogr. 22(4):592-7, 1998
