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KEY FACTS
Terminology
Imaging
Top Differential Diagnoses
Pathology
Clinical Issues
Diagnostic Checklist
TERMINOLOGY
Abbreviations
Swyer-James-MacLeod syndrome (SJM)
Synonyms
Swyer-James syndrome
MacLeod syndrome
Controversy regarding eponyms to be ascribed to syndrome
MacLeod presented report of 9 patients with "abnormal transradiancy of 1 lung," which was "small or normal size" at British Thoracic Society meeting in London in February of 1952
Swyer and James published case of "unilateral pulmonary emphysema" in 1953
MacLeod published his work in 1954
Definitions
Constrictive bronchiolitis as result of childhood infectious bronchiolitis (typically from Adenovirus infection)
Constrictive bronchiolitis: Irreversible obstructive small airways disease characterized by submucosal and peribronchiolar fibrosis with resultant destruction and obliterative scarring of small airways
Mosaic attenuation (perfusion): Geographic regions of increased parenchymal attenuation with intrinsic large pulmonary vessels adjacent to regions of decreased attenuation with intrinsic small pulmonary vessels
IMAGING
General Features
Radiographic Findings
CT Findings
Nuclear Medicine Findings
Imaging Recommendations
DIFFERENTIAL DIAGNOSIS
PATHOLOGY
General Features
Staging, Grading, & Classification
Microscopic Features
CLINICAL ISSUES
Presentation
Demographics
Natural History & Prognosis
Treatment
DIAGNOSTIC CHECKLIST
Consider
Selected References
Behrendt A et al: Swyer-James-MacLeod Syndrome 2020
Gomes de Farias LP et al: Swyer-James-MacLeod syndrome: the hyperlucent lung. Radiol Cardiothorac Imaging. 2(3):e190246, 2020
Griffiths P et al: Swyer-James-MacLeod syndrome and pulmonary arteriovenous malformations: a rare combination. BMJ Case Rep. 13(1), 2020
Kawasuji H et al: Multimodal imaging findings in an adult case of Swyer-James-MacLeod syndrome. Respirol Case Rep. 5(4):e00236, 2017
Winningham PJ et al: Bronchiolitis: a practical approach for the general radiologist. Radiographics. 37(3):777-94, 2017
Chaucer B et al: Swyer-James-Macleod syndrome: a rare finding and important differential in the ED setting. Am J Emerg Med. 34(7):1329.e3-4, 2016
Milanese G et al: Lung volume reduction of pulmonary emphysema: the radiologist task. Curr Opin Pulm Med. 22(2):179-86, 2016
Yu J: Postinfectious bronchiolitis obliterans in children: lessons from bronchiolitis obliterans after lung transplantation and hematopoietic stem cell transplantation. Korean J Pediatr. 58(12):459-65, 2015
Mosquera RA et al: Dysanaptic growth of lung and airway in children with post-infectious bronchiolitis obliterans. Clin Respir J. 8(1):63-71, 2014
Xie BQ et al: Ventilation/perfusion scintigraphy in children with post-infectious bronchiolitis obliterans: a pilot study. PLoS One. 9(5):e98381, 2014
Wasilewska E et al: Unilateral hyperlucent lung in children. AJR Am J Roentgenol. 198(5):W400-14, 2012
Champs NS et al: Post-infectious bronchiolitis obliterans in children. J Pediatr (Rio J). 87(3):187-98, 2011
Dillman JR et al: Expanding upon the unilateral hyperlucent hemithorax in children. Radiographics. 31(3):723-41, 2011
Lucaya J et al: Spectrum of manifestations of Swyer-James-MacLeod syndrome. J Comput Assist Tomogr. 22(4):592-7, 1998
Related Anatomy
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Related Differential Diagnoses
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References
Tables
Tables
KEY FACTS
Terminology
Imaging
Top Differential Diagnoses
Pathology
Clinical Issues
Diagnostic Checklist
TERMINOLOGY
Abbreviations
Swyer-James-MacLeod syndrome (SJM)
Synonyms
Swyer-James syndrome
MacLeod syndrome
Controversy regarding eponyms to be ascribed to syndrome
MacLeod presented report of 9 patients with "abnormal transradiancy of 1 lung," which was "small or normal size" at British Thoracic Society meeting in London in February of 1952
Swyer and James published case of "unilateral pulmonary emphysema" in 1953
MacLeod published his work in 1954
Definitions
Constrictive bronchiolitis as result of childhood infectious bronchiolitis (typically from Adenovirus infection)
Constrictive bronchiolitis: Irreversible obstructive small airways disease characterized by submucosal and peribronchiolar fibrosis with resultant destruction and obliterative scarring of small airways
Mosaic attenuation (perfusion): Geographic regions of increased parenchymal attenuation with intrinsic large pulmonary vessels adjacent to regions of decreased attenuation with intrinsic small pulmonary vessels
IMAGING
General Features
Radiographic Findings
CT Findings
Nuclear Medicine Findings
Imaging Recommendations
DIFFERENTIAL DIAGNOSIS
PATHOLOGY
General Features
Staging, Grading, & Classification
Microscopic Features
CLINICAL ISSUES
Presentation
Demographics
Natural History & Prognosis
Treatment
DIAGNOSTIC CHECKLIST
Consider
Selected References
Behrendt A et al: Swyer-James-MacLeod Syndrome 2020
Gomes de Farias LP et al: Swyer-James-MacLeod syndrome: the hyperlucent lung. Radiol Cardiothorac Imaging. 2(3):e190246, 2020
Griffiths P et al: Swyer-James-MacLeod syndrome and pulmonary arteriovenous malformations: a rare combination. BMJ Case Rep. 13(1), 2020
Kawasuji H et al: Multimodal imaging findings in an adult case of Swyer-James-MacLeod syndrome. Respirol Case Rep. 5(4):e00236, 2017
Winningham PJ et al: Bronchiolitis: a practical approach for the general radiologist. Radiographics. 37(3):777-94, 2017
Chaucer B et al: Swyer-James-Macleod syndrome: a rare finding and important differential in the ED setting. Am J Emerg Med. 34(7):1329.e3-4, 2016
Milanese G et al: Lung volume reduction of pulmonary emphysema: the radiologist task. Curr Opin Pulm Med. 22(2):179-86, 2016
Yu J: Postinfectious bronchiolitis obliterans in children: lessons from bronchiolitis obliterans after lung transplantation and hematopoietic stem cell transplantation. Korean J Pediatr. 58(12):459-65, 2015
Mosquera RA et al: Dysanaptic growth of lung and airway in children with post-infectious bronchiolitis obliterans. Clin Respir J. 8(1):63-71, 2014
Xie BQ et al: Ventilation/perfusion scintigraphy in children with post-infectious bronchiolitis obliterans: a pilot study. PLoS One. 9(5):e98381, 2014
Wasilewska E et al: Unilateral hyperlucent lung in children. AJR Am J Roentgenol. 198(5):W400-14, 2012
Champs NS et al: Post-infectious bronchiolitis obliterans in children. J Pediatr (Rio J). 87(3):187-98, 2011
Dillman JR et al: Expanding upon the unilateral hyperlucent hemithorax in children. Radiographics. 31(3):723-41, 2011