Acquired unilateral pulmonary hypoplasia thought to result from childhood viral infection
Results in small, hyperexpanded lung with relatively ↓ vascularity & (rarely) bronchiectasis
Imaging findings may appear as early as 9 months after initial infectious insult
IMAGING
General Features
Radiographic Findings
CT Findings
Imaging Recommendations
DIFFERENTIAL DIAGNOSIS
PATHOLOGY
General Features
CLINICAL ISSUES
Presentation
Demographics
Natural History & Prognosis
Treatment
Selected References
Behrendt A et al: Swyer-James-MacLeod syndrome. StatPearls, 2021
Cherian SV et al: Lung hyperlucency: a clinical-radiologic algorithmic approach to diagnosis. Chest. 157(1):119-41, 2020
Gomes de Farias LP et al: Swyer-James-MacLeod syndrome: the hyperlucent lung. Radiol Cardiothorac Imaging. 2(3):e190246, 2020
Machado D et al: Swyer-James-Macleod syndrome as a rare cause of unilateral hyperlucent lung: three case reports. Medicine (Baltimore). 98(6):e14269, 2019
Hamada S et al: Swyer-James-Macleod syndrome: the differential diagnosis of unilateral hyperlucency. Intern Med. 57(17):2591-2, 2018
Dirweesh A et al: A unilateral hyperlucent lung - Swyer-James syndrome: a case report and literature review. Respir Med Case Rep. 20:104-6, 2017
Wasilewska E et al: Unilateral hyperlucent lung in children. AJR Am J Roentgenol. 198(5):W400-14, 2012
Acquired unilateral pulmonary hypoplasia thought to result from childhood viral infection
Results in small, hyperexpanded lung with relatively ↓ vascularity & (rarely) bronchiectasis
Imaging findings may appear as early as 9 months after initial infectious insult
IMAGING
General Features
Radiographic Findings
CT Findings
Imaging Recommendations
DIFFERENTIAL DIAGNOSIS
PATHOLOGY
General Features
CLINICAL ISSUES
Presentation
Demographics
Natural History & Prognosis
Treatment
Selected References
Behrendt A et al: Swyer-James-MacLeod syndrome. StatPearls, 2021
Cherian SV et al: Lung hyperlucency: a clinical-radiologic algorithmic approach to diagnosis. Chest. 157(1):119-41, 2020
Gomes de Farias LP et al: Swyer-James-MacLeod syndrome: the hyperlucent lung. Radiol Cardiothorac Imaging. 2(3):e190246, 2020
Machado D et al: Swyer-James-Macleod syndrome as a rare cause of unilateral hyperlucent lung: three case reports. Medicine (Baltimore). 98(6):e14269, 2019
Hamada S et al: Swyer-James-Macleod syndrome: the differential diagnosis of unilateral hyperlucency. Intern Med. 57(17):2591-2, 2018
Dirweesh A et al: A unilateral hyperlucent lung - Swyer-James syndrome: a case report and literature review. Respir Med Case Rep. 20:104-6, 2017
Wasilewska E et al: Unilateral hyperlucent lung in children. AJR Am J Roentgenol. 198(5):W400-14, 2012
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